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TTLL5 (tubulin tyrosine ligase like 5)

Identity

Alias_namesKIAA0998
KIAA0998
tubulin tyrosine ligase-like family member 5
Other aliasCORD19
STAMP
HGNC (Hugo) TTLL5
LocusID (NCBI) 23093
Atlas_Id 75315
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 75661208 and ends at 75955082 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IFT43 (14q24.3) / TTLL5 (14q24.3)RP4-761I2.2 () / TTLL5 (14q24.3)SMIM13 (6p24.2) / TTLL5 (14q24.3)
TMED10 (14q24.3) / TTLL5 (14q24.3)TTLL5 (14q24.3) / AATF (17q12)TTLL5 (14q24.3) / CXADR (21q21.1)
TTLL5 (14q24.3) / NAPA (19q13.32)TTLL5 (14q24.3) / TSHR (14q31.1)TTLL5 (14q24.3) / TTLL5 (14q24.3)
TTLL5 (14q24.3) / YLPM1 (14q24.3)RP4-761I2.2 TTLL5TMED10 TTLL5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTLL5   19963
Cards
Entrez_Gene (NCBI)TTLL5  23093  tubulin tyrosine ligase like 5
AliasesCORD19; KIAA0998; STAMP
GeneCards (Weizmann)TTLL5
Ensembl hg19 (Hinxton)ENSG00000119685 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119685 [Gene_View]  chr14:75661208-75955082 [Contig_View]  TTLL5 [Vega]
ICGC DataPortalENSG00000119685
TCGA cBioPortalTTLL5
AceView (NCBI)TTLL5
Genatlas (Paris)TTLL5
WikiGenes23093
SOURCE (Princeton)TTLL5
Genetics Home Reference (NIH)TTLL5
Genomic and cartography
GoldenPath hg38 (UCSC)TTLL5  -     chr14:75661208-75955082 +  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTLL5  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblTTLL5 - 14q24.3 [CytoView hg19]  TTLL5 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBITTLL5 [Mapview hg19]  TTLL5 [Mapview hg38]
OMIM612268   615860   
Gene and transcription
Genbank (Entrez)AB023215 AK021879 AK024259 AK309748 AL133586
RefSeq transcript (Entrez)NM_015072
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTLL5
Cluster EST : UnigeneHs.709609 [ NCBI ]
CGAP (NCI)Hs.709609
Alternative Splicing GalleryENSG00000119685
Gene ExpressionTTLL5 [ NCBI-GEO ]   TTLL5 [ EBI - ARRAY_EXPRESS ]   TTLL5 [ SEEK ]   TTLL5 [ MEM ]
Gene Expression Viewer (FireBrowse)TTLL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23093
GTEX Portal (Tissue expression)TTLL5
Human Protein AtlasENSG00000119685-TTLL5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6EMB2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6EMB2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6EMB2
Splice isoforms : SwissVarQ6EMB2
Catalytic activity : Enzyme6.-.-.- [ Enzyme-Expasy ]   6.-.-.-6.-.-.- [ IntEnz-EBI ]   6.-.-.- [ BRENDA ]   6.-.-.- [ KEGG ]   
PhosPhoSitePlusQ6EMB2
Domaine pattern : Prosite (Expaxy)TTL (PS51221)   
Domains : Interpro (EBI)TTL/TTLL_fam   
Domain families : Pfam (Sanger)TTL (PF03133)   
Domain families : Pfam (NCBI)pfam03133   
Conserved Domain (NCBI)TTLL5
DMDM Disease mutations23093
Blocks (Seattle)TTLL5
SuperfamilyQ6EMB2
Human Protein Atlas [tissue]ENSG00000119685-TTLL5 [tissue]
Peptide AtlasQ6EMB2
HPRD08309
IPIIPI00456634   IPI00456994   IPI00007914   IPI01018939   IPI00815918   IPI00939598   IPI01025776   IPI01025886   IPI01025544   IPI01025552   
Protein Interaction databases
DIP (DOE-UCLA)Q6EMB2
IntAct (EBI)Q6EMB2
FunCoupENSG00000119685
BioGRIDTTLL5
STRING (EMBL)TTLL5
ZODIACTTLL5
Ontologies - Pathways
QuickGOQ6EMB2
Ontology : AmiGOATP binding  nucleus  centrosome  cytosol  microtubule  plasma membrane  cilium  transcription, DNA-templated  sperm axoneme assembly  fertilization  ligase activity  protein polyglutamylation  retina development in camera-type eye  
Ontology : EGO-EBIATP binding  nucleus  centrosome  cytosol  microtubule  plasma membrane  cilium  transcription, DNA-templated  sperm axoneme assembly  fertilization  ligase activity  protein polyglutamylation  retina development in camera-type eye  
NDEx NetworkTTLL5
Atlas of Cancer Signalling NetworkTTLL5
Wikipedia pathwaysTTLL5
Orthology - Evolution
OrthoDB23093
GeneTree (enSembl)ENSG00000119685
Phylogenetic Trees/Animal Genes : TreeFamTTLL5
HOVERGENQ6EMB2
HOGENOMQ6EMB2
Homologs : HomoloGeneTTLL5
Homology/Alignments : Family Browser (UCSC)TTLL5
Gene fusions - Rearrangements
Fusion: TCGARP4-761I2.2 TTLL5
Fusion: TCGATMED10 TTLL5
Fusion: Tumor Portal TTLL5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTLL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTLL5
dbVarTTLL5
ClinVarTTLL5
1000_GenomesTTLL5 
Exome Variant ServerTTLL5
ExAC (Exome Aggregation Consortium)ENSG00000119685
GNOMAD BrowserENSG00000119685
Genetic variants : HAPMAP23093
Genomic Variants (DGV)TTLL5 [DGVbeta]
DECIPHERTTLL5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTLL5 
Mutations
ICGC`DataPostalTTLL5 
TCGA Data PortalTTLL5 
Broad Tumor PortalTTLL5
OASIS PortalTTLL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTLL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTLL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTLL5
DgiDB (Drug Gene Interaction Database)TTLL5
DoCM (Curated mutations)TTLL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTLL5 (select a term)
intoGenTTLL5
Cancer3DTTLL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612268    615860   
Orphanet1843   
MedgenTTLL5
Genetic Testing Registry TTLL5
NextProtQ6EMB2 [Medical]
TSGene23093
GENETestsTTLL5
Target ValidationTTLL5
Huge Navigator TTLL5 [HugePedia]
snp3D : Map Gene to Disease23093
BioCentury BCIQTTLL5
ClinGenTTLL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23093
Chemical/Pharm GKB GenePA164742694
Clinical trialTTLL5
Miscellaneous
canSAR (ICR)TTLL5 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTLL5
EVEXTTLL5
GoPubMedTTLL5
iHOPTTLL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:34:30 CET 2017

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