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TTLL6 (tubulin tyrosine ligase like 6)

Identity

Alias_namestubulin tyrosine ligase-like family member 6
Alias_symbol (synonym)FLJ35808
Other aliasTTL.6
HGNC (Hugo) TTLL6
LocusID (NCBI) 284076
Atlas_Id 75316
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 48762231 and ends at 48817107 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TOB1 (17q21.33) / TTLL6 (17q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTLL6   26664
Cards
Entrez_Gene (NCBI)TTLL6  284076  tubulin tyrosine ligase like 6
AliasesTTL.6
GeneCards (Weizmann)TTLL6
Ensembl hg19 (Hinxton)ENSG00000170703 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170703 [Gene_View]  chr17:48762231-48817107 [Contig_View]  TTLL6 [Vega]
ICGC DataPortalENSG00000170703
TCGA cBioPortalTTLL6
AceView (NCBI)TTLL6
Genatlas (Paris)TTLL6
WikiGenes284076
SOURCE (Princeton)TTLL6
Genetics Home Reference (NIH)TTLL6
Genomic and cartography
GoldenPath hg38 (UCSC)TTLL6  -     chr17:48762231-48817107 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTLL6  -     17q21.32   [Description]    (hg19-Feb_2009)
EnsemblTTLL6 - 17q21.32 [CytoView hg19]  TTLL6 - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBITTLL6 [Mapview hg19]  TTLL6 [Mapview hg38]
OMIM610849   
Gene and transcription
Genbank (Entrez)AK093127 AK097392 AK302952 AK310321 AL834151
RefSeq transcript (Entrez)NM_001130918 NM_173623
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTLL6
Cluster EST : UnigeneHs.91930 [ NCBI ]
CGAP (NCI)Hs.91930
Alternative Splicing GalleryENSG00000170703
Gene ExpressionTTLL6 [ NCBI-GEO ]   TTLL6 [ EBI - ARRAY_EXPRESS ]   TTLL6 [ SEEK ]   TTLL6 [ MEM ]
Gene Expression Viewer (FireBrowse)TTLL6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284076
GTEX Portal (Tissue expression)TTLL6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N841   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N841  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N841
Splice isoforms : SwissVarQ8N841
Catalytic activity : Enzyme6.-.-.- [ Enzyme-Expasy ]   6.-.-.-6.-.-.- [ IntEnz-EBI ]   6.-.-.- [ BRENDA ]   6.-.-.- [ KEGG ]   
PhosPhoSitePlusQ8N841
Domaine pattern : Prosite (Expaxy)TTL (PS51221)   
Domains : Interpro (EBI)TTL/TTLL_fam    TTLL6   
Domain families : Pfam (Sanger)TTL (PF03133)   
Domain families : Pfam (NCBI)pfam03133   
Conserved Domain (NCBI)TTLL6
DMDM Disease mutations284076
Blocks (Seattle)TTLL6
SuperfamilyQ8N841
Human Protein AtlasENSG00000170703
Peptide AtlasQ8N841
HPRD08763
IPIIPI00967625   IPI00297940   IPI00796660   IPI00924455   IPI00470379   IPI00927309   IPI00927105   
Protein Interaction databases
DIP (DOE-UCLA)Q8N841
IntAct (EBI)Q8N841
FunCoupENSG00000170703
BioGRIDTTLL6
STRING (EMBL)TTLL6
ZODIACTTLL6
Ontologies - Pathways
QuickGOQ8N841
Ontology : AmiGOmicrotubule bundle formation  positive regulation of cilium movement  protein binding  ATP binding  cytoplasm  microtubule  tubulin binding  protein polyglutamylation  ciliary basal body  microtubule severing  protein-glutamic acid ligase activity  
Ontology : EGO-EBImicrotubule bundle formation  positive regulation of cilium movement  protein binding  ATP binding  cytoplasm  microtubule  tubulin binding  protein polyglutamylation  ciliary basal body  microtubule severing  protein-glutamic acid ligase activity  
NDEx NetworkTTLL6
Atlas of Cancer Signalling NetworkTTLL6
Wikipedia pathwaysTTLL6
Orthology - Evolution
OrthoDB284076
GeneTree (enSembl)ENSG00000170703
Phylogenetic Trees/Animal Genes : TreeFamTTLL6
HOVERGENQ8N841
HOGENOMQ8N841
Homologs : HomoloGeneTTLL6
Homology/Alignments : Family Browser (UCSC)TTLL6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTLL6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTLL6
dbVarTTLL6
ClinVarTTLL6
1000_GenomesTTLL6 
Exome Variant ServerTTLL6
ExAC (Exome Aggregation Consortium)TTLL6 (select the gene name)
Genetic variants : HAPMAP284076
Genomic Variants (DGV)TTLL6 [DGVbeta]
DECIPHERTTLL6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTLL6 
Mutations
ICGC Data PortalTTLL6 
TCGA Data PortalTTLL6 
Broad Tumor PortalTTLL6
OASIS PortalTTLL6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTLL6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTLL6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTLL6
DgiDB (Drug Gene Interaction Database)TTLL6
DoCM (Curated mutations)TTLL6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTLL6 (select a term)
intoGenTTLL6
Cancer3DTTLL6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610849   
Orphanet
MedgenTTLL6
Genetic Testing Registry TTLL6
NextProtQ8N841 [Medical]
TSGene284076
GENETestsTTLL6
Huge Navigator TTLL6 [HugePedia]
snp3D : Map Gene to Disease284076
BioCentury BCIQTTLL6
ClinGenTTLL6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284076
Chemical/Pharm GKB GenePA143485662
Clinical trialTTLL6
Miscellaneous
canSAR (ICR)TTLL6 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTLL6
EVEXTTLL6
GoPubMedTTLL6
iHOPTTLL6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:00:11 CEST 2017

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