Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TTLL7 (tubulin tyrosine ligase like 7)

Identity

Alias_namestubulin tyrosine ligase-like family member 7
Alias_symbol (synonym)FLJ23033
Other alias-
HGNC (Hugo) TTLL7
LocusID (NCBI) 79739
Atlas_Id 75317
Location 1p31.1  [Link to chromosome band 1p31]
Location_base_pair Starts at 83865032 and ends at 83999187 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PHTF1 (1p13.2) / TTLL7 (1p31.1)TTLL7 (1p31.1) / GNG5 (1p22.3)TTLL7 (1p31.1) / SAMD13 (1p31.1)
TTLL7 (1p31.1) / TERT (5p15.33)TTLL7 TERTTTLL7 SAMD13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTLL7   26242
Cards
Entrez_Gene (NCBI)TTLL7  79739  tubulin tyrosine ligase like 7
Aliases
GeneCards (Weizmann)TTLL7
Ensembl hg19 (Hinxton)ENSG00000137941 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137941 [Gene_View]  chr1:83865032-83999187 [Contig_View]  TTLL7 [Vega]
ICGC DataPortalENSG00000137941
TCGA cBioPortalTTLL7
AceView (NCBI)TTLL7
Genatlas (Paris)TTLL7
WikiGenes79739
SOURCE (Princeton)TTLL7
Genetics Home Reference (NIH)TTLL7
Genomic and cartography
GoldenPath hg38 (UCSC)TTLL7  -     chr1:83865032-83999187 -  1p31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTLL7  -     1p31.1   [Description]    (hg19-Feb_2009)
EnsemblTTLL7 - 1p31.1 [CytoView hg19]  TTLL7 - 1p31.1 [CytoView hg38]
Mapping of homologs : NCBITTLL7 [Mapview hg19]  TTLL7 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI374651 AK026686 AK094174 AK126792 AK128604
RefSeq transcript (Entrez)NM_001350214 NM_001350215 NM_024686
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TTLL7
Cluster EST : UnigeneHs.594267 [ NCBI ]
CGAP (NCI)Hs.594267
Alternative Splicing GalleryENSG00000137941
Gene ExpressionTTLL7 [ NCBI-GEO ]   TTLL7 [ EBI - ARRAY_EXPRESS ]   TTLL7 [ SEEK ]   TTLL7 [ MEM ]
Gene Expression Viewer (FireBrowse)TTLL7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79739
GTEX Portal (Tissue expression)TTLL7
Human Protein AtlasENSG00000137941-TTLL7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZT98   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZT98  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZT98
Splice isoforms : SwissVarQ6ZT98
PhosPhoSitePlusQ6ZT98
Domaine pattern : Prosite (Expaxy)TTL (PS51221)   
Domains : Interpro (EBI)TTL/TTLL_fam   
Domain families : Pfam (Sanger)TTL (PF03133)   
Domain families : Pfam (NCBI)pfam03133   
Conserved Domain (NCBI)TTLL7
DMDM Disease mutations79739
Blocks (Seattle)TTLL7
PDB (SRS)4YLR    4YLS   
PDB (PDBSum)4YLR    4YLS   
PDB (IMB)4YLR    4YLS   
PDB (RSDB)4YLR    4YLS   
Structural Biology KnowledgeBase4YLR    4YLS   
SCOP (Structural Classification of Proteins)4YLR    4YLS   
CATH (Classification of proteins structures)4YLR    4YLS   
SuperfamilyQ6ZT98
Human Protein Atlas [tissue]ENSG00000137941-TTLL7 [tissue]
Peptide AtlasQ6ZT98
HPRD08013
IPIIPI00514795   IPI00643434   IPI00640491   IPI00977489   IPI00983088   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZT98
IntAct (EBI)Q6ZT98
FunCoupENSG00000137941
BioGRIDTTLL7
STRING (EMBL)TTLL7
ZODIACTTLL7
Ontologies - Pathways
QuickGOQ6ZT98
Ontology : AmiGOATP binding  cytoplasm  microtubule  cilium  nervous system development  protein polyglutamylation  cell differentiation  dendrite  alpha-tubulin binding  perikaryon  beta-tubulin binding  tubulin-glutamic acid ligase activity  
Ontology : EGO-EBIATP binding  cytoplasm  microtubule  cilium  nervous system development  protein polyglutamylation  cell differentiation  dendrite  alpha-tubulin binding  perikaryon  beta-tubulin binding  tubulin-glutamic acid ligase activity  
NDEx NetworkTTLL7
Atlas of Cancer Signalling NetworkTTLL7
Wikipedia pathwaysTTLL7
Orthology - Evolution
OrthoDB79739
GeneTree (enSembl)ENSG00000137941
Phylogenetic Trees/Animal Genes : TreeFamTTLL7
HOVERGENQ6ZT98
HOGENOMQ6ZT98
Homologs : HomoloGeneTTLL7
Homology/Alignments : Family Browser (UCSC)TTLL7
Gene fusions - Rearrangements
Fusion: TCGA_MDACCTTLL7 TERT
Fusion: TCGA_MDACCTTLL7 SAMD13
Tumor Fusion PortalTTLL7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTLL7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTLL7
dbVarTTLL7
ClinVarTTLL7
1000_GenomesTTLL7 
Exome Variant ServerTTLL7
ExAC (Exome Aggregation Consortium)ENSG00000137941
GNOMAD BrowserENSG00000137941
Genetic variants : HAPMAP79739
Genomic Variants (DGV)TTLL7 [DGVbeta]
DECIPHERTTLL7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTLL7 
Mutations
ICGC Data PortalTTLL7 
TCGA Data PortalTTLL7 
Broad Tumor PortalTTLL7
OASIS PortalTTLL7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTLL7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTTLL7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TTLL7
DgiDB (Drug Gene Interaction Database)TTLL7
DoCM (Curated mutations)TTLL7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTLL7 (select a term)
intoGenTTLL7
Cancer3DTTLL7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTTLL7
MedgenTTLL7
Genetic Testing Registry TTLL7
NextProtQ6ZT98 [Medical]
TSGene79739
GENETestsTTLL7
Target ValidationTTLL7
Huge Navigator TTLL7 [HugePedia]
snp3D : Map Gene to Disease79739
BioCentury BCIQTTLL7
ClinGenTTLL7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79739
Chemical/Pharm GKB GenePA142670678
Clinical trialTTLL7
Miscellaneous
canSAR (ICR)TTLL7 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTLL7
EVEXTTLL7
GoPubMedTTLL7
iHOPTTLL7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:03:34 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.