Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TTPA (tocopherol (alpha) transfer protein)

Identity

Other namesATTP
AVED
TTP1
alphaTTP
HGNC (Hugo) TTPA
LocusID (NCBI) 7274
Location 8q12.3
Location_base_pair Starts at 63972048 and ends at 63998612 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TTPA   12404
Cards
Entrez_Gene (NCBI)TTPA  7274  tocopherol (alpha) transfer protein
GeneCards (Weizmann)TTPA
Ensembl (Hinxton)ENSG00000137561 [Gene_View]  chr8:63972048-63998612 [Contig_View]  TTPA [Vega]
ICGC DataPortalENSG00000137561
cBioPortalTTPA
AceView (NCBI)TTPA
Genatlas (Paris)TTPA
WikiGenes7274
SOURCE (Princeton)NM_000370
Genomic and cartography
GoldenPath (UCSC)TTPA  -  8q12.3   chr8:63972048-63998612 -  8q12.3   [Description]    (hg19-Feb_2009)
EnsemblTTPA - 8q12.3 [CytoView]
Mapping of homologs : NCBITTPA [Mapview]
OMIM277460   600415   
Gene and transcription
Genbank (Entrez)BC041784 BC058000 D49488 HQ447611 U21938
RefSeq transcript (Entrez)NM_000370
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_016123 NT_008183 NW_001839132 NW_004929339
Consensus coding sequences : CCDS (NCBI)TTPA
Cluster EST : UnigeneHs.69049 [ NCBI ]
CGAP (NCI)Hs.69049
Alternative Splicing : Fast-db (Paris)GSHG0029608
Alternative Splicing GalleryENSG00000137561
Gene ExpressionTTPA [ NCBI-GEO ]     TTPA [ SEEK ]   TTPA [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49638 (Uniprot)
NextProtP49638  [Medical]
With graphics : InterProP49638
Splice isoforms : SwissVarP49638 (Swissvar)
Domaine pattern : Prosite (Expaxy)CRAL_TRIO (PS50191)   
Domains : Interpro (EBI)CRAL-bd_toc_tran [organisation]   CRAL-TRIO_dom [organisation]   CRAL/TRIO_N_dom [organisation]  
Related proteins : CluSTrP49638
Domain families : Pfam (Sanger)CRAL_TRIO (PF00650)    CRAL_TRIO_N (PF03765)   
Domain families : Pfam (NCBI)pfam00650    pfam03765   
Domain families : Smart (EMBL)CRAL_TRIO_N (SM01100)  SEC14 (SM00516)  
DMDM Disease mutations7274
Blocks (Seattle)P49638
PDB (SRS)1OIP    1OIZ    1R5L   
PDB (PDBSum)1OIP    1OIZ    1R5L   
PDB (IMB)1OIP    1OIZ    1R5L   
PDB (RSDB)1OIP    1OIZ    1R5L   
Human Protein AtlasENSG00000137561 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP49638
HPRD02685
IPIIPI00027692   
Protein Interaction databases
DIP (DOE-UCLA)P49638
IntAct (EBI)P49638
FunCoupENSG00000137561
BioGRIDTTPA
InParanoidP49638
Interologous Interaction database P49638
IntegromeDBTTPA
STRING (EMBL)TTPA
Ontologies - Pathways
Ontology : AmiGOembryonic placenta development  transporter activity  phosphatidylinositol-4,5-bisphosphate binding  late endosome  cytosol  lipid metabolic process  transport  response to nutrient  vitamin E binding  response to pH  response to toxic substance  vitamin E metabolic process  phosphatidylinositol-3,4-bisphosphate binding  intermembrane transport  vitamin transport  intracellular pH reduction  negative regulation of cell death  negative regulation of establishment of blood-brain barrier  
Ontology : EGO-EBIembryonic placenta development  transporter activity  phosphatidylinositol-4,5-bisphosphate binding  late endosome  cytosol  lipid metabolic process  transport  response to nutrient  vitamin E binding  response to pH  response to toxic substance  vitamin E metabolic process  phosphatidylinositol-3,4-bisphosphate binding  intermembrane transport  vitamin transport  intracellular pH reduction  negative regulation of cell death  negative regulation of establishment of blood-brain barrier  
Protein Interaction DatabaseTTPA
Wikipedia pathwaysTTPA
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TTPA
snp3D : Map Gene to Disease7274
SNP (GeneSNP Utah)TTPA
SNP : HGBaseTTPA
Genetic variants : HAPMAPTTPA
Exome VariantTTPA
1000_GenomesTTPA 
ICGC programENSG00000137561 
Somatic Mutations in Cancer : COSMICTTPA 
CONAN: Copy Number AnalysisTTPA 
Mutations and Diseases : HGMDTTPA
Mutations and Diseases : intOGenTTPA
Genomic VariantsTTPA  TTPA [DGVbeta]
dbVarTTPA
ClinVarTTPA
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM277460    600415   
MedgenTTPA
GENETestsTTPA
Disease Genetic AssociationTTPA
Huge Navigator TTPA [HugePedia]  TTPA [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTTPA
Homology/Alignments : Family Browser (UCSC)TTPA
Phylogenetic Trees/Animal Genes : TreeFamTTPA
Chemical/Protein Interactions : CTD7274
Chemical/Pharm GKB GenePA37068
Clinical trialTTPA
Cancer Resource (Charite)ENSG00000137561
Other databases
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
CoreMineTTPA
iHOPTTPA
OncoSearchTTPA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:23:59 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.