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TTPA (tocopherol (alpha) transfer protein)

Identity

Other namesATTP
AVED
TTP1
alphaTTP
HGNC (Hugo) TTPA
LocusID (NCBI) 7274
Atlas_Id 50857
Location 8q12.3  [Link to chromosome band 8q12]
Location_base_pair Starts at 63972048 and ends at 63998612 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TTPA   12404
Cards
Entrez_Gene (NCBI)TTPA  7274  tocopherol (alpha) transfer protein
AliasesATTP; AVED; TTP1; alphaTTP
GeneCards (Weizmann)TTPA
Ensembl hg19 (Hinxton)ENSG00000137561 [Gene_View]  chr8:63972048-63998612 [Contig_View]  TTPA [Vega]
Ensembl hg38 (Hinxton)ENSG00000137561 [Gene_View]  chr8:63972048-63998612 [Contig_View]  TTPA [Vega]
ICGC DataPortalENSG00000137561
TCGA cBioPortalTTPA
AceView (NCBI)TTPA
Genatlas (Paris)TTPA
WikiGenes7274
SOURCE (Princeton)TTPA
Genomic and cartography
GoldenPath hg19 (UCSC)TTPA  -     chr8:63972048-63998612 -  8q12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TTPA  -     8q12.3   [Description]    (hg38-Dec_2013)
EnsemblTTPA - 8q12.3 [CytoView hg19]  TTPA - 8q12.3 [CytoView hg38]
Mapping of homologs : NCBITTPA [Mapview hg19]  TTPA [Mapview hg38]
OMIM277460   600415   
Gene and transcription
Genbank (Entrez)BC041784 BC058000 D49488 HQ447611 U21938
RefSeq transcript (Entrez)NM_000370
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_016123 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)TTPA
Cluster EST : UnigeneHs.69049 [ NCBI ]
CGAP (NCI)Hs.69049
Alternative Splicing GalleryENSG00000137561
Gene ExpressionTTPA [ NCBI-GEO ]   TTPA [ EBI - ARRAY_EXPRESS ]   TTPA [ SEEK ]   TTPA [ MEM ]
Gene Expression Viewer (FireBrowse)TTPA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7274
GTEX Portal (Tissue expression)TTPA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49638 (Uniprot)
NextProtP49638  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49638
Splice isoforms : SwissVarP49638 (Swissvar)
PhosPhoSitePlusP49638
Domaine pattern : Prosite (Expaxy)CRAL_TRIO (PS50191)   
Domains : Interpro (EBI)CRAL-bd_toc_tran    CRAL-TRIO_dom    CRAL/TRIO_N_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)CRAL_TRIO_N (SM01100)  SEC14 (SM00516)  
DMDM Disease mutations7274
Blocks (Seattle)TTPA
PDB (SRS)1OIP    1OIZ    1R5L   
PDB (PDBSum)1OIP    1OIZ    1R5L   
PDB (IMB)1OIP    1OIZ    1R5L   
PDB (RSDB)1OIP    1OIZ    1R5L   
Structural Biology KnowledgeBase1OIP    1OIZ    1R5L   
SCOP (Structural Classification of Proteins)1OIP    1OIZ    1R5L   
CATH (Classification of proteins structures)1OIP    1OIZ    1R5L   
SuperfamilyP49638
Human Protein AtlasENSG00000137561
Peptide AtlasP49638
HPRD02685
IPIIPI00027692   
Protein Interaction databases
DIP (DOE-UCLA)P49638
IntAct (EBI)P49638
FunCoupENSG00000137561
BioGRIDTTPA
STRING (EMBL)TTPA
ZODIACTTPA
Ontologies - Pathways
QuickGOP49638
Ontology : AmiGOembryonic placenta development  transporter activity  protein binding  phosphatidylinositol-4,5-bisphosphate binding  late endosome  cytosol  lipid metabolic process  transport  response to nutrient  vitamin E binding  response to pH  response to toxic substance  vitamin E metabolic process  phosphatidylinositol-3,4-bisphosphate binding  intermembrane transport  vitamin transport  intracellular pH reduction  negative regulation of cell death  negative regulation of establishment of blood-brain barrier  
Ontology : EGO-EBIembryonic placenta development  transporter activity  protein binding  phosphatidylinositol-4,5-bisphosphate binding  late endosome  cytosol  lipid metabolic process  transport  response to nutrient  vitamin E binding  response to pH  response to toxic substance  vitamin E metabolic process  phosphatidylinositol-3,4-bisphosphate binding  intermembrane transport  vitamin transport  intracellular pH reduction  negative regulation of cell death  negative regulation of establishment of blood-brain barrier  
NDEx Network
Atlas of Cancer Signalling NetworkTTPA
Wikipedia pathwaysTTPA
Orthology - Evolution
OrthoDB7274
GeneTree (enSembl)ENSG00000137561
Phylogenetic Trees/Animal Genes : TreeFamTTPA
Homologs : HomoloGeneTTPA
Homology/Alignments : Family Browser (UCSC)TTPA
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTTPA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTPA
dbVarTTPA
ClinVarTTPA
1000_GenomesTTPA 
Exome Variant ServerTTPA
ExAC (Exome Aggregation Consortium)TTPA (select the gene name)
Genetic variants : HAPMAP7274
Genomic Variants (DGV)TTPA [DGVbeta]
Mutations
ICGC Data PortalTTPA 
TCGA Data PortalTTPA 
Broad Tumor PortalTTPA
OASIS PortalTTPA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTPA 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch TTPA
DgiDB (Drug Gene Interaction Database)TTPA
DoCM (Curated mutations)TTPA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TTPA (select a term)
intoGenTTPA
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:63972048-63998612  ENSG00000137561
CONAN: Copy Number AnalysisTTPA 
Mutations and Diseases : HGMDTTPA
OMIM277460    600415   
MedgenTTPA
Genetic Testing Registry TTPA
NextProtP49638 [Medical]
TSGene7274
GENETestsTTPA
Huge Navigator TTPA [HugePedia]
snp3D : Map Gene to Disease7274
BioCentury BCIQTTPA
ClinGenTTPA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7274
Chemical/Pharm GKB GenePA37068
Clinical trialTTPA
Miscellaneous
canSAR (ICR)TTPA (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTTPA
EVEXTTPA
GoPubMedTTPA
iHOPTTPA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:10:52 CEST 2016

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