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TTYH3 (tweety family member 3)

Identity

Alias (NCBI)-
HGNC (Hugo) TTYH3
HGNC Alias symbKIAA1691
HGNC Previous nametweety homolog 3 (Drosophila)
LocusID (NCBI) 80727
Atlas_Id 75356
Location 7p22.3  [Link to chromosome band 7p22]
Location_base_pair Starts at 2631986 and ends at 2664802 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C7orf50 (7p22.3) / TTYH3 (7p22.3)MAD1L1 (7p22.3) / TTYH3 (7p22.3)TTYH3 (7p22.3) / C7orf50 (7p22.3)
TTYH3 (7p22.3) / ING1 (13q34)TTYH3 (7p22.3) / MAD1L1 (7p22.3)TTYH3 (7p22.3) / NOC4L (12q24.33)
TTYH3 (7p22.3) / SNX22 (15q22.31)TTYH3 (7p22.3) / SPTAN1 (9q34.11)TTYH3 (7p22.3) / TTYH3 (7p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(7;7)(p22;p22) TTYH3/MAD1L1
t(7;7)(p22;p22) TTYH3/MAD1L1


External links

 

Nomenclature
HGNC (Hugo)TTYH3   22222
Cards
Entrez_Gene (NCBI)TTYH3    tweety family member 3
Aliases
GeneCards (Weizmann)TTYH3
Ensembl hg19 (Hinxton)ENSG00000136295 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136295 [Gene_View]  ENSG00000136295 [Sequence]  chr7:2631986-2664802 [Contig_View]  TTYH3 [Vega]
ICGC DataPortalENSG00000136295
TCGA cBioPortalTTYH3
AceView (NCBI)TTYH3
Genatlas (Paris)TTYH3
SOURCE (Princeton)TTYH3
Genetics Home Reference (NIH)TTYH3
Genomic and cartography
GoldenPath hg38 (UCSC)TTYH3  -     chr7:2631986-2664802 +  7p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TTYH3  -     7p22.3   [Description]    (hg19-Feb_2009)
GoldenPathTTYH3 - 7p22.3 [CytoView hg19]  TTYH3 - 7p22.3 [CytoView hg38]
ImmunoBaseENSG00000136295
Genome Data Viewer NCBITTYH3 [Mapview hg19]  
OMIM608919   
Gene and transcription
Genbank (Entrez)AB051478 AB162931 AF318350 AK074158 AK096851
RefSeq transcript (Entrez)NM_025250
Consensus coding sequences : CCDS (NCBI)TTYH3
Gene ExpressionTTYH3 [ NCBI-GEO ]   TTYH3 [ EBI - ARRAY_EXPRESS ]   TTYH3 [ SEEK ]   TTYH3 [ MEM ]
Gene Expression Viewer (FireBrowse)TTYH3 [ Firebrowse - Broad ]
GenevisibleExpression of TTYH3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80727
GTEX Portal (Tissue expression)TTYH3
Human Protein AtlasENSG00000136295-TTYH3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0H2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0H2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0H2
PhosPhoSitePlusQ9C0H2
Domains : Interpro (EBI)Tweety   
Domain families : Pfam (Sanger)Tweety (PF04906)   
Domain families : Pfam (NCBI)pfam04906   
Conserved Domain (NCBI)TTYH3
SuperfamilyQ9C0H2
AlphaFold pdb e-kbQ9C0H2   
Human Protein Atlas [tissue]ENSG00000136295-TTYH3 [tissue]
HPRD12333
Protein Interaction databases
DIP (DOE-UCLA)Q9C0H2
IntAct (EBI)Q9C0H2
BioGRIDTTYH3
STRING (EMBL)TTYH3
ZODIACTTYH3
Ontologies - Pathways
QuickGOQ9C0H2
Ontology : AmiGOintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  plasma membrane  chloride transport  ion transmembrane transport  chloride channel complex  extracellular exosome  volume-sensitive chloride channel activity  
Ontology : EGO-EBIintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  plasma membrane  chloride transport  ion transmembrane transport  chloride channel complex  extracellular exosome  volume-sensitive chloride channel activity  
NDEx NetworkTTYH3
Atlas of Cancer Signalling NetworkTTYH3
Wikipedia pathwaysTTYH3
Orthology - Evolution
OrthoDB80727
GeneTree (enSembl)ENSG00000136295
Phylogenetic Trees/Animal Genes : TreeFamTTYH3
Homologs : HomoloGeneTTYH3
Homology/Alignments : Family Browser (UCSC)TTYH3
Gene fusions - Rearrangements
Fusion : QuiverTTYH3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTTYH3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TTYH3
dbVarTTYH3
ClinVarTTYH3
MonarchTTYH3
1000_GenomesTTYH3 
Exome Variant ServerTTYH3
GNOMAD BrowserENSG00000136295
Varsome BrowserTTYH3
ACMGTTYH3 variants
VarityQ9C0H2
Genomic Variants (DGV)TTYH3 [DGVbeta]
DECIPHERTTYH3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTTYH3 
Mutations
ICGC Data PortalTTYH3 
TCGA Data PortalTTYH3 
Broad Tumor PortalTTYH3
OASIS PortalTTYH3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTTYH3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTTYH3
Mutations and Diseases : HGMDTTYH3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTTYH3
DgiDB (Drug Gene Interaction Database)TTYH3
DoCM (Curated mutations)TTYH3
CIViC (Clinical Interpretations of Variants in Cancer)TTYH3
Cancer3DTTYH3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608919   
Orphanet
DisGeNETTTYH3
MedgenTTYH3
Genetic Testing Registry TTYH3
NextProtQ9C0H2 [Medical]
GENETestsTTYH3
Target ValidationTTYH3
Huge Navigator TTYH3 [HugePedia]
ClinGenTTYH3
Clinical trials, drugs, therapy
MyCancerGenomeTTYH3
Protein Interactions : CTDTTYH3
Pharm GKB GenePA134908427
PharosQ9C0H2
Clinical trialTTYH3
Miscellaneous
canSAR (ICR)TTYH3
HarmonizomeTTYH3
DataMed IndexTTYH3
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTTYH3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:27:31 CEST 2021

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