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TUB (tubby bipartite transcription factor)

Identity

Alias_namestubby (mouse) homolog
tubby homolog (mouse)
Alias_symbol (synonym)rd5
Other aliasRDOB
HGNC (Hugo) TUB
LocusID (NCBI) 7275
Atlas_Id 75357
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 8038633 and ends at 8106107 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUB   12406
Cards
Entrez_Gene (NCBI)TUB  7275  tubby bipartite transcription factor
AliasesRDOB; rd5
GeneCards (Weizmann)TUB
Ensembl hg19 (Hinxton)ENSG00000166402 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166402 [Gene_View]  chr11:8038633-8106107 [Contig_View]  TUB [Vega]
ICGC DataPortalENSG00000166402
TCGA cBioPortalTUB
AceView (NCBI)TUB
Genatlas (Paris)TUB
WikiGenes7275
SOURCE (Princeton)TUB
Genetics Home Reference (NIH)TUB
Genomic and cartography
GoldenPath hg38 (UCSC)TUB  -     chr11:8038633-8106107 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUB  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblTUB - 11p15.4 [CytoView hg19]  TUB - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBITUB [Mapview hg19]  TUB [Mapview hg38]
OMIM601197   616188   
Gene and transcription
Genbank (Entrez)AB209618 AK293528 BC036400 BC075031 BC075032
RefSeq transcript (Entrez)NM_003320 NM_177972
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUB
Cluster EST : UnigeneHs.733193 [ NCBI ]
CGAP (NCI)Hs.733193
Alternative Splicing GalleryENSG00000166402
Gene ExpressionTUB [ NCBI-GEO ]   TUB [ EBI - ARRAY_EXPRESS ]   TUB [ SEEK ]   TUB [ MEM ]
Gene Expression Viewer (FireBrowse)TUB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7275
GTEX Portal (Tissue expression)TUB
Human Protein AtlasENSG00000166402-TUB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50607   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50607  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50607
Splice isoforms : SwissVarP50607
PhosPhoSitePlusP50607
Domaine pattern : Prosite (Expaxy)TUB_1 (PS01200)    TUB_2 (PS01201)   
Domains : Interpro (EBI)Tubby_C    Tubby_C-like    Tubby_C_CS    Tubby_N   
Domain families : Pfam (Sanger)Tub (PF01167)    Tub_N (PF16322)   
Domain families : Pfam (NCBI)pfam01167    pfam16322   
Conserved Domain (NCBI)TUB
DMDM Disease mutations7275
Blocks (Seattle)TUB
PDB (SRS)1S31   
PDB (PDBSum)1S31   
PDB (IMB)1S31   
PDB (RSDB)1S31   
Structural Biology KnowledgeBase1S31   
SCOP (Structural Classification of Proteins)1S31   
CATH (Classification of proteins structures)1S31   
SuperfamilyP50607
Human Protein Atlas [tissue]ENSG00000166402-TUB [tissue]
Peptide AtlasP50607
HPRD03121
IPIIPI00000660   IPI00178718   IPI00975516   
Protein Interaction databases
DIP (DOE-UCLA)P50607
IntAct (EBI)P50607
FunCoupENSG00000166402
BioGRIDTUB
STRING (EMBL)TUB
ZODIACTUB
Ontologies - Pathways
QuickGOP50607
Ontology : AmiGOextracellular region  nucleus  cytoplasm  cytosol  plasma membrane  cilium  phagocytosis, recognition  sensory perception of sound  response to hormone  protein complex binding  phosphatidylinositol binding  photoreceptor cell maintenance  positive regulation of phagocytosis  retina development in camera-type eye  receptor localization to non-motile cilium  protein localization to photoreceptor outer segment  
Ontology : EGO-EBIextracellular region  nucleus  cytoplasm  cytosol  plasma membrane  cilium  phagocytosis, recognition  sensory perception of sound  response to hormone  protein complex binding  phosphatidylinositol binding  photoreceptor cell maintenance  positive regulation of phagocytosis  retina development in camera-type eye  receptor localization to non-motile cilium  protein localization to photoreceptor outer segment  
Pathways : BIOCARTAG-Protein Signaling Through Tubby Proteins [Genes]   
NDEx NetworkTUB
Atlas of Cancer Signalling NetworkTUB
Wikipedia pathwaysTUB
Orthology - Evolution
OrthoDB7275
GeneTree (enSembl)ENSG00000166402
Phylogenetic Trees/Animal Genes : TreeFamTUB
HOVERGENP50607
HOGENOMP50607
Homologs : HomoloGeneTUB
Homology/Alignments : Family Browser (UCSC)TUB
Gene fusions - Rearrangements
Tumor Fusion PortalTUB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUB
dbVarTUB
ClinVarTUB
1000_GenomesTUB 
Exome Variant ServerTUB
ExAC (Exome Aggregation Consortium)ENSG00000166402
GNOMAD BrowserENSG00000166402
Genetic variants : HAPMAP7275
Genomic Variants (DGV)TUB [DGVbeta]
DECIPHERTUB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUB 
Mutations
ICGC Data PortalTUB 
TCGA Data PortalTUB 
Broad Tumor PortalTUB
OASIS PortalTUB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUB
DgiDB (Drug Gene Interaction Database)TUB
DoCM (Curated mutations)TUB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUB (select a term)
intoGenTUB
Cancer3DTUB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601197    616188   
Orphanet659   
DisGeNETTUB
MedgenTUB
Genetic Testing Registry TUB
NextProtP50607 [Medical]
TSGene7275
GENETestsTUB
Target ValidationTUB
Huge Navigator TUB [HugePedia]
snp3D : Map Gene to Disease7275
BioCentury BCIQTUB
ClinGenTUB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7275
Chemical/Pharm GKB GenePA37070
Clinical trialTUB
Miscellaneous
canSAR (ICR)TUB (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUB
EVEXTUB
GoPubMedTUB
iHOPTUB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 21 13:25:36 CET 2017

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