TUB (TUB bipartite transcription factor)

2014-11-01  

Identity

HGNC
TUB
LOCATION
11p15.4
LOCUSID
7275
ALIAS
RDOB,rd5

Other Information

Locus ID:

NCBI: 7275
MIM: 601197
HGNC: 12406
Ensembl: ENSG00000166402

Variants:

dbSNP: 7275
ClinVar: 7275
TCGA: ENSG00000166402
COSMIC: TUB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166402ENST00000299506P50607
ENSG00000166402ENST00000305253P50607
ENSG00000166402ENST00000534099E9PQR4

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
113754832001G-protein signaling through tubby proteins.113
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
209784722010Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.71
105916371999Implication of tubby proteins as transcription factors by structure-based functional analysis.49
200806502010Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.46
198370632010Identification of tubby and tubby-like protein 1 as eat-me signals by phage display.29
190587892009A common variant in DRD3 receptor is associated with autism spectrum disorder.19
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
190774382009Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.10
164437712006Identification of TUB as a novel candidate gene influencing body weight in humans.9

Citation

Dessen P

TUB (TUB bipartite transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75357/tub