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TUBA1C (tubulin alpha 1c)

Identity

Alias_namesTUBA6
tubulin
Alias_symbol (synonym)MGC14580
MGC10851
bcm948
Other alias
HGNC (Hugo) TUBA1C
LocusID (NCBI) 84790
Atlas_Id 52889
Location 12q13.12  [Link to chromosome band 12q13]
Location_base_pair Starts at 49621709 and ends at 49667121 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CCDC109B (4q25) / TUBA1C (12q13.12)NCF2 (1q25.3) / TUBA1C (12q13.12)TUBA1C (12q13.12) / PCGF2 (17q12)
TUBA1C (12q13.12) / RPS23 (5q14.2)TUBA1C (12q13.12) / UBB (17p11.2)TUBA1C (12q13.12) / VPS39 (15q15.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUBA1C   20768
Cards
Entrez_Gene (NCBI)TUBA1C  84790  tubulin alpha 1c
AliasesTUBA6; bcm948
GeneCards (Weizmann)TUBA1C
Ensembl hg19 (Hinxton)ENSG00000167553 [Gene_View]  chr12:49621709-49667121 [Contig_View]  TUBA1C [Vega]
Ensembl hg38 (Hinxton)ENSG00000167553 [Gene_View]  chr12:49621709-49667121 [Contig_View]  TUBA1C [Vega]
ICGC DataPortalENSG00000167553
TCGA cBioPortalTUBA1C
AceView (NCBI)TUBA1C
Genatlas (Paris)TUBA1C
WikiGenes84790
SOURCE (Princeton)TUBA1C
Genetics Home Reference (NIH)TUBA1C
Genomic and cartography
GoldenPath hg19 (UCSC)TUBA1C  -     chr12:49621709-49667121 +  12q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TUBA1C  -     12q13.12   [Description]    (hg38-Dec_2013)
EnsemblTUBA1C - 12q13.12 [CytoView hg19]  TUBA1C - 12q13.12 [CytoView hg38]
Mapping of homologs : NCBITUBA1C [Mapview hg19]  TUBA1C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK223024 AK293589 AL539200 AW150119 BC004949
RefSeq transcript (Entrez)NM_001303114 NM_001303115 NM_001303116 NM_001303117 NM_032704
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)TUBA1C
Cluster EST : UnigeneHs.739076 [ NCBI ]
CGAP (NCI)Hs.739076
Alternative Splicing GalleryENSG00000167553
Gene ExpressionTUBA1C [ NCBI-GEO ]   TUBA1C [ EBI - ARRAY_EXPRESS ]   TUBA1C [ SEEK ]   TUBA1C [ MEM ]
Gene Expression Viewer (FireBrowse)TUBA1C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84790
GTEX Portal (Tissue expression)TUBA1C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQE3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQE3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQE3
Splice isoforms : SwissVarQ9BQE3
PhosPhoSitePlusQ9BQE3
Domaine pattern : Prosite (Expaxy)TUBULIN (PS00227)   
Domains : Interpro (EBI)Alpha_tubulin    Tub_FtsZ_C    Tubulin    Tubulin/FtsZ_2-layer-sand-dom    Tubulin_C    Tubulin_CS    Tubulin_FtsZ_GTPase   
Domain families : Pfam (Sanger)Tubulin (PF00091)    Tubulin_C (PF03953)   
Domain families : Pfam (NCBI)pfam00091    pfam03953   
Domain families : Smart (EMBL)Tubulin (SM00864)  Tubulin_C (SM00865)  
Conserved Domain (NCBI)TUBA1C
DMDM Disease mutations84790
Blocks (Seattle)TUBA1C
SuperfamilyQ9BQE3
Human Protein AtlasENSG00000167553
Peptide AtlasQ9BQE3
HPRD06747
IPIIPI00218343   IPI00387144   IPI00166768   IPI01021207   IPI01020672   IPI01020940   
Protein Interaction databases
DIP (DOE-UCLA)Q9BQE3
IntAct (EBI)Q9BQE3
FunCoupENSG00000167553
BioGRIDTUBA1C
STRING (EMBL)TUBA1C
ZODIACTUBA1C
Ontologies - Pathways
QuickGOQ9BQE3
Ontology : AmiGOGTPase activity  structural molecule activity  structural constituent of cytoskeleton  protein binding  GTP binding  nucleus  cytoplasm  microtubule  microtubule-based process  metabolic process  cytoskeleton-dependent intracellular transport  vesicle  cell division  
Ontology : EGO-EBIGTPase activity  structural molecule activity  structural constituent of cytoskeleton  protein binding  GTP binding  nucleus  cytoplasm  microtubule  microtubule-based process  metabolic process  cytoskeleton-dependent intracellular transport  vesicle  cell division  
Pathways : KEGGPhagosome    Gap junction    Pathogenic Escherichia coli infection   
NDEx NetworkTUBA1C
Atlas of Cancer Signalling NetworkTUBA1C
Wikipedia pathwaysTUBA1C
Orthology - Evolution
OrthoDB84790
GeneTree (enSembl)ENSG00000167553
Phylogenetic Trees/Animal Genes : TreeFamTUBA1C
HOVERGENQ9BQE3
HOGENOMQ9BQE3
Homologs : HomoloGeneTUBA1C
Homology/Alignments : Family Browser (UCSC)TUBA1C
Gene fusions - Rearrangements
Fusion : MitelmanTUBA1C/PCGF2 [12q13.12/17q12]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUBA1C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUBA1C
dbVarTUBA1C
ClinVarTUBA1C
1000_GenomesTUBA1C 
Exome Variant ServerTUBA1C
ExAC (Exome Aggregation Consortium)TUBA1C (select the gene name)
Genetic variants : HAPMAP84790
Genomic Variants (DGV)TUBA1C [DGVbeta]
DECIPHER (Syndromes)12:49621709-49667121  ENSG00000167553
CONAN: Copy Number AnalysisTUBA1C 
Mutations
ICGC Data PortalTUBA1C 
TCGA Data PortalTUBA1C 
Broad Tumor PortalTUBA1C
OASIS PortalTUBA1C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUBA1C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUBA1C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUBA1C
DgiDB (Drug Gene Interaction Database)TUBA1C
DoCM (Curated mutations)TUBA1C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUBA1C (select a term)
intoGenTUBA1C
Cancer3DTUBA1C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTUBA1C
Genetic Testing Registry TUBA1C
NextProtQ9BQE3 [Medical]
TSGene84790
GENETestsTUBA1C
Huge Navigator TUBA1C [HugePedia]
snp3D : Map Gene to Disease84790
BioCentury BCIQTUBA1C
ClinGenTUBA1C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84790
Chemical/Pharm GKB GenePA162407345
Clinical trialTUBA1C
Miscellaneous
canSAR (ICR)TUBA1C (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUBA1C
EVEXTUBA1C
GoPubMedTUBA1C
iHOPTUBA1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:32:46 CET 2017

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