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TUBB1 (tubulin beta 1 class VI)

Identity

Alias (NCBI)-
HGNC (Hugo) TUBB1
HGNC Alias symbdJ543J19.4
HGNC Alias nameclass VI beta-tubulin
HGNC Previous nametubulin, beta 1
LocusID (NCBI) 81027
Atlas_Id 43959
Location 20q13.32  [Link to chromosome band 20q13]
Location_base_pair Starts at 59019429 and ends at 59026654 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RABGAP1L (1q25.1) / TUBB1 (20q13.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;20)(q25;q13) RABGAP1L/TUBB1


External links

 

Nomenclature
HGNC (Hugo)TUBB1   16257
LRG (Locus Reference Genomic)LRG_581
Cards
Entrez_Gene (NCBI)TUBB1    tubulin beta 1 class VI
Aliases
GeneCards (Weizmann)TUBB1
Ensembl hg19 (Hinxton)ENSG00000101162 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101162 [Gene_View]  ENSG00000101162 [Sequence]  chr20:59019429-59026654 [Contig_View]  TUBB1 [Vega]
ICGC DataPortalENSG00000101162
TCGA cBioPortalTUBB1
AceView (NCBI)TUBB1
Genatlas (Paris)TUBB1
SOURCE (Princeton)TUBB1
Genetics Home Reference (NIH)TUBB1
Genomic and cartography
GoldenPath hg38 (UCSC)TUBB1  -     chr20:59019429-59026654 +  20q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUBB1  -     20q13.32   [Description]    (hg19-Feb_2009)
GoldenPathTUBB1 - 20q13.32 [CytoView hg19]  TUBB1 - 20q13.32 [CytoView hg38]
ImmunoBaseENSG00000101162
Genome Data Viewer NCBITUBB1 [Mapview hg19]  
OMIM612901   613112   
Gene and transcription
Genbank (Entrez)AJ292757 BC033679 BI821931
RefSeq transcript (Entrez)NM_030773
Consensus coding sequences : CCDS (NCBI)TUBB1
Gene ExpressionTUBB1 [ NCBI-GEO ]   TUBB1 [ EBI - ARRAY_EXPRESS ]   TUBB1 [ SEEK ]   TUBB1 [ MEM ]
Gene Expression Viewer (FireBrowse)TUBB1 [ Firebrowse - Broad ]
GenevisibleExpression of TUBB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81027
GTEX Portal (Tissue expression)TUBB1
Human Protein AtlasENSG00000101162-TUBB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4B7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4B7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4B7
PhosPhoSitePlusQ9H4B7
Domaine pattern : Prosite (Expaxy)TUBULIN (PS00227)    TUBULIN_B_AUTOREG (PS00228)   
Domains : Interpro (EBI)Beta-tubulin_BS    Beta_tubulin    Tub_FtsZ_C    Tubulin    Tubulin/FtsZ_2-layer-sand-dom    Tubulin/FtsZ_C_sf    Tubulin/FtsZ_GTPase_sf    Tubulin_C    Tubulin_CS    Tubulin_FtsZ_GTPase   
Domain families : Pfam (Sanger)Tubulin (PF00091)    Tubulin_C (PF03953)   
Domain families : Pfam (NCBI)pfam00091    pfam03953   
Domain families : Smart (EMBL)Tubulin (SM00864)  Tubulin_C (SM00865)  
Conserved Domain (NCBI)TUBB1
SuperfamilyQ9H4B7
AlphaFold pdb e-kbQ9H4B7   
Human Protein Atlas [tissue]ENSG00000101162-TUBB1 [tissue]
HPRD18243
Protein Interaction databases
DIP (DOE-UCLA)Q9H4B7
IntAct (EBI)Q9H4B7
BioGRIDTUBB1
STRING (EMBL)TUBB1
ZODIACTUBB1
Ontologies - Pathways
QuickGOQ9H4B7
Ontology : AmiGOmicrotubule cytoskeleton organization  mitotic cell cycle  structural constituent of cytoskeleton  GTP binding  cytoplasm  cytoplasm  microtubule  spindle assembly  extracellular exosome  
Ontology : EGO-EBImicrotubule cytoskeleton organization  mitotic cell cycle  structural constituent of cytoskeleton  GTP binding  cytoplasm  cytoplasm  microtubule  spindle assembly  extracellular exosome  
Pathways : KEGGPhagosome    Gap junction    Pathogenic Escherichia coli infection   
NDEx NetworkTUBB1
Atlas of Cancer Signalling NetworkTUBB1
Wikipedia pathwaysTUBB1
Orthology - Evolution
OrthoDB81027
GeneTree (enSembl)ENSG00000101162
Phylogenetic Trees/Animal Genes : TreeFamTUBB1
Homologs : HomoloGeneTUBB1
Homology/Alignments : Family Browser (UCSC)TUBB1
Gene fusions - Rearrangements
Fusion : MitelmanRABGAP1L/TUBB1 [1q25.1/20q13.32]  
Fusion : QuiverTUBB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUBB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUBB1
dbVarTUBB1
ClinVarTUBB1
MonarchTUBB1
1000_GenomesTUBB1 
Exome Variant ServerTUBB1
GNOMAD BrowserENSG00000101162
Varsome BrowserTUBB1
ACMGTUBB1 variants
VarityQ9H4B7
Genomic Variants (DGV)TUBB1 [DGVbeta]
DECIPHERTUBB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUBB1 
Mutations
ICGC Data PortalTUBB1 
TCGA Data PortalTUBB1 
Broad Tumor PortalTUBB1
OASIS PortalTUBB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUBB1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTUBB1
Mutations and Diseases : HGMDTUBB1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTUBB1
DgiDB (Drug Gene Interaction Database)TUBB1
DoCM (Curated mutations)TUBB1
CIViC (Clinical Interpretations of Variants in Cancer)TUBB1
Cancer3DTUBB1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612901    613112   
Orphanet17007   
DisGeNETTUBB1
MedgenTUBB1
Genetic Testing Registry TUBB1
NextProtQ9H4B7 [Medical]
GENETestsTUBB1
Target ValidationTUBB1
Huge Navigator TUBB1 [HugePedia]
ClinGenTUBB1
Clinical trials, drugs, therapy
MyCancerGenomeTUBB1
Protein Interactions : CTDTUBB1
Pharm GKB GenePA38100
PharosQ9H4B7
Clinical trialTUBB1
Miscellaneous
canSAR (ICR)TUBB1
HarmonizomeTUBB1
DataMed IndexTUBB1
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTUBB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:49 CEST 2021

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