Identity
HGNC
LOCATION
6p25.2
LOCUSID
ALIAS
CDCBM7,PMGYSA,bA506K6.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 347733
MIM: 612850
HGNC: 30829
Ensembl: ENSG00000137285
Variants:
dbSNP: 347733
ClinVar: 347733
TCGA: ENSG00000137285
COSMIC: TUBB2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137285 | ENST00000259818 | Q9BVA1 |
| ENSG00000137285 | ENST00000259818 | A0A384MEE3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36872411 | 2023 | TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1. | 1 |
| 36872411 | 2023 | TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1. | 1 |
| 33734457 | 2021 | Periprostatic adipose tissue promotes prostate cancer resistance to docetaxel by paracrine IGF-1 upregulation of TUBB2B beta-tubulin isoform. | 24 |
| 34592644 | 2021 | A novel family illustrating the mild phenotypic spectrum of TUBB2B variants. | 1 |
| 33734457 | 2021 | Periprostatic adipose tissue promotes prostate cancer resistance to docetaxel by paracrine IGF-1 upregulation of TUBB2B beta-tubulin isoform. | 24 |
| 34592644 | 2021 | A novel family illustrating the mild phenotypic spectrum of TUBB2B variants. | 1 |
| 30621030 | 2019 | Over-Expression of βII-Tubulin and Especially Its Localization in Cell Nuclei Correlates with Poorer Outcomes in Colorectal Cancer. | 10 |
| 31432180 | 2019 | Upregulation of MAPK10, TUBB2B and RASL11B may contribute to the development of neuroblastoma. | 4 |
| 30621030 | 2019 | Over-Expression of βII-Tubulin and Especially Its Localization in Cell Nuclei Correlates with Poorer Outcomes in Colorectal Cancer. | 10 |
| 31432180 | 2019 | Upregulation of MAPK10, TUBB2B and RASL11B may contribute to the development of neuroblastoma. | 4 |
| 28013290 | 2017 | Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. | 6 |
| 28013290 | 2017 | Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. | 6 |
| 26732629 | 2016 | De novo TUBB2B mutation causes fetal akinesia deformation sequence with microlissencephaly: An unusual presentation of tubulinopathy. | 6 |
| 27306797 | 2016 | Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length. | 34 |
| 26732629 | 2016 | De novo TUBB2B mutation causes fetal akinesia deformation sequence with microlissencephaly: An unusual presentation of tubulinopathy. | 6 |
Citation
Dessen P
TUBB2B (tubulin beta 2B class IIb)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49846/tubb2b
