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TUBB6 (tubulin beta 6 class V)

Identity

Alias_namestubulin, beta 6
tubulin, beta 6 class V
Alias_symbol (synonym)MGC4083
HsT1601
Other aliasTUBB-5
HGNC (Hugo) TUBB6
LocusID (NCBI) 84617
Atlas_Id 51758
Location 18p11.21  [Link to chromosome band 18p11]
Location_base_pair Starts at 12307669 and ends at 12326616 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADI1 (2p25.3) / TUBB6 (18p11.21)IL4I1 (19q13.33) / TUBB6 (18p11.21)RYR2 (1q43) / TUBB6 (18p11.21)
TUBB6 (18p11.21) / ROBO1 (3p12.3)TUBB6 18p11.21 / ROBO1 3p12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUBB6   20776
Cards
Entrez_Gene (NCBI)TUBB6  84617  tubulin beta 6 class V
AliasesHsT1601; TUBB-5
GeneCards (Weizmann)TUBB6
Ensembl hg19 (Hinxton)ENSG00000176014 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176014 [Gene_View]  chr18:12307669-12326616 [Contig_View]  TUBB6 [Vega]
ICGC DataPortalENSG00000176014
TCGA cBioPortalTUBB6
AceView (NCBI)TUBB6
Genatlas (Paris)TUBB6
WikiGenes84617
SOURCE (Princeton)TUBB6
Genetics Home Reference (NIH)TUBB6
Genomic and cartography
GoldenPath hg38 (UCSC)TUBB6  -     chr18:12307669-12326616 +  18p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUBB6  -     18p11.21   [Description]    (hg19-Feb_2009)
EnsemblTUBB6 - 18p11.21 [CytoView hg19]  TUBB6 - 18p11.21 [CytoView hg38]
Mapping of homologs : NCBITUBB6 [Mapview hg19]  TUBB6 [Mapview hg38]
OMIM615103   
Gene and transcription
Genbank (Entrez)AK001295 AK022340 AK092677 AK098440 AK298196
RefSeq transcript (Entrez)NM_001303524 NM_001303525 NM_001303526 NM_001303527 NM_001303528 NM_001303529 NM_001303530 NM_032525
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUBB6
Cluster EST : UnigeneHs.744066 [ NCBI ]
CGAP (NCI)Hs.744066
Alternative Splicing GalleryENSG00000176014
Gene ExpressionTUBB6 [ NCBI-GEO ]   TUBB6 [ EBI - ARRAY_EXPRESS ]   TUBB6 [ SEEK ]   TUBB6 [ MEM ]
Gene Expression Viewer (FireBrowse)TUBB6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84617
GTEX Portal (Tissue expression)TUBB6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUF5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUF5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUF5
Splice isoforms : SwissVarQ9BUF5
PhosPhoSitePlusQ9BUF5
Domaine pattern : Prosite (Expaxy)TUBULIN (PS00227)    TUBULIN_B_AUTOREG (PS00228)   
Domains : Interpro (EBI)Beta-tubulin_BS    Beta_tubulin    Tub_FtsZ_C    Tubulin    Tubulin/FtsZ_2-layer-sand-dom    Tubulin_C    Tubulin_CS    Tubulin_FtsZ_GTPase   
Domain families : Pfam (Sanger)Tubulin (PF00091)    Tubulin_C (PF03953)   
Domain families : Pfam (NCBI)pfam00091    pfam03953   
Domain families : Smart (EMBL)Tubulin (SM00864)  Tubulin_C (SM00865)  
Conserved Domain (NCBI)TUBB6
DMDM Disease mutations84617
Blocks (Seattle)TUBB6
SuperfamilyQ9BUF5
Human Protein AtlasENSG00000176014
Peptide AtlasQ9BUF5
HPRD11349
IPIIPI00930130   IPI01011853   IPI00908469   IPI00646779   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUF5
IntAct (EBI)Q9BUF5
FunCoupENSG00000176014
BioGRIDTUBB6
STRING (EMBL)TUBB6
ZODIACTUBB6
Ontologies - Pathways
QuickGOQ9BUF5
Ontology : AmiGOmolecular_function  GTPase activity  structural constituent of cytoskeleton  GTP binding  nucleus  cytoplasm  microtubule  cytoskeleton organization  microtubule-based process  microtubule cytoskeleton  extracellular exosome  
Ontology : EGO-EBImolecular_function  GTPase activity  structural constituent of cytoskeleton  GTP binding  nucleus  cytoplasm  microtubule  cytoskeleton organization  microtubule-based process  microtubule cytoskeleton  extracellular exosome  
Pathways : KEGGPhagosome    Gap junction    Pathogenic Escherichia coli infection   
NDEx NetworkTUBB6
Atlas of Cancer Signalling NetworkTUBB6
Wikipedia pathwaysTUBB6
Orthology - Evolution
OrthoDB84617
GeneTree (enSembl)ENSG00000176014
Phylogenetic Trees/Animal Genes : TreeFamTUBB6
HOVERGENQ9BUF5
HOGENOMQ9BUF5
Homologs : HomoloGeneTUBB6
Homology/Alignments : Family Browser (UCSC)TUBB6
Gene fusions - Rearrangements
Fusion : MitelmanTUBB6/ROBO1 [18p11.21/3p12.3]  
Fusion: TCGATUBB6 18p11.21 ROBO1 3p12.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUBB6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUBB6
dbVarTUBB6
ClinVarTUBB6
1000_GenomesTUBB6 
Exome Variant ServerTUBB6
ExAC (Exome Aggregation Consortium)TUBB6 (select the gene name)
Genetic variants : HAPMAP84617
Genomic Variants (DGV)TUBB6 [DGVbeta]
DECIPHERTUBB6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUBB6 
Mutations
ICGC Data PortalTUBB6 
TCGA Data PortalTUBB6 
Broad Tumor PortalTUBB6
OASIS PortalTUBB6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUBB6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUBB6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUBB6
DgiDB (Drug Gene Interaction Database)TUBB6
DoCM (Curated mutations)TUBB6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUBB6 (select a term)
intoGenTUBB6
Cancer3DTUBB6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615103   
Orphanet
MedgenTUBB6
Genetic Testing Registry TUBB6
NextProtQ9BUF5 [Medical]
TSGene84617
GENETestsTUBB6
Huge Navigator TUBB6 [HugePedia]
snp3D : Map Gene to Disease84617
BioCentury BCIQTUBB6
ClinGenTUBB6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84617
Chemical/Pharm GKB GenePA128394736
Clinical trialTUBB6
Miscellaneous
canSAR (ICR)TUBB6 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUBB6
EVEXTUBB6
GoPubMedTUBB6
iHOPTUBB6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:42:45 CEST 2017

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