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TUBB8 (tubulin beta 8 class VIII)

Identity

Alias_namestubulin, beta 8 class VIII
Alias_symbol (synonym)bA631M21.2
Other aliasOOMD
OOMD2
HGNC (Hugo) TUBB8
LocusID (NCBI) 347688
Atlas_Id 75368
Location 10p15.3  [Link to chromosome band 10p15]
Location_base_pair Starts at 46888 and ends at 49238 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUBB8   20773
Cards
Entrez_Gene (NCBI)TUBB8  347688  tubulin beta 8 class VIII
AliasesOOMD; OOMD2; bA631M21.2
GeneCards (Weizmann)TUBB8
Ensembl hg19 (Hinxton)ENSG00000261456 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000261456 [Gene_View]  chr10:46888-49238 [Contig_View]  TUBB8 [Vega]
ICGC DataPortalENSG00000261456
TCGA cBioPortalTUBB8
AceView (NCBI)TUBB8
Genatlas (Paris)TUBB8
WikiGenes347688
SOURCE (Princeton)TUBB8
Genetics Home Reference (NIH)TUBB8
Genomic and cartography
GoldenPath hg38 (UCSC)TUBB8  -     chr10:46888-49238 -  10p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUBB8  -     10p15.3   [Description]    (hg19-Feb_2009)
EnsemblTUBB8 - 10p15.3 [CytoView hg19]  TUBB8 - 10p15.3 [CytoView hg38]
Mapping of homologs : NCBITUBB8 [Mapview hg19]  TUBB8 [Mapview hg38]
OMIM616768   616780   
Gene and transcription
Genbank (Entrez)BC101270 BC101271 BC156319 BC157066
RefSeq transcript (Entrez)NM_001164154 NM_177987
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUBB8
Cluster EST : UnigeneHs.532659 [ NCBI ]
CGAP (NCI)Hs.532659
Alternative Splicing GalleryENSG00000261456
Gene ExpressionTUBB8 [ NCBI-GEO ]   TUBB8 [ EBI - ARRAY_EXPRESS ]   TUBB8 [ SEEK ]   TUBB8 [ MEM ]
Gene Expression Viewer (FireBrowse)TUBB8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)347688
GTEX Portal (Tissue expression)TUBB8
Human Protein AtlasENSG00000261456-TUBB8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ3ZCM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ3ZCM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ3ZCM7
Splice isoforms : SwissVarQ3ZCM7
PhosPhoSitePlusQ3ZCM7
Domaine pattern : Prosite (Expaxy)TUBULIN (PS00227)    TUBULIN_B_AUTOREG (PS00228)   
Domains : Interpro (EBI)Beta-tubulin_BS    Beta_tubulin    Tub_FtsZ_C    Tubulin    Tubulin/FtsZ_2-layer-sand-dom    Tubulin_C    Tubulin_CS    Tubulin_FtsZ_GTPase   
Domain families : Pfam (Sanger)Tubulin (PF00091)    Tubulin_C (PF03953)   
Domain families : Pfam (NCBI)pfam00091    pfam03953   
Domain families : Smart (EMBL)Tubulin (SM00864)  Tubulin_C (SM00865)  
Conserved Domain (NCBI)TUBB8
DMDM Disease mutations347688
Blocks (Seattle)TUBB8
SuperfamilyQ3ZCM7
Human Protein Atlas [tissue]ENSG00000261456-TUBB8 [tissue]
Peptide AtlasQ3ZCM7
HPRD18244
IPIIPI00292496   IPI00945532   IPI00514047   IPI00945362   IPI01013807   IPI00947433   
Protein Interaction databases
DIP (DOE-UCLA)Q3ZCM7
IntAct (EBI)Q3ZCM7
FunCoupENSG00000261456
BioGRIDTUBB8
STRING (EMBL)TUBB8
ZODIACTUBB8
Ontologies - Pathways
QuickGOQ3ZCM7
Ontology : AmiGOoocyte maturation  molecular_function  GTPase activity  structural constituent of cytoskeleton  GTP binding  cytoplasm  microtubule  spindle assembly involved in female meiosis  biological_process  microtubule cytoskeleton  extracellular exosome  meiotic spindle  
Ontology : EGO-EBIoocyte maturation  molecular_function  GTPase activity  structural constituent of cytoskeleton  GTP binding  cytoplasm  microtubule  spindle assembly involved in female meiosis  biological_process  microtubule cytoskeleton  extracellular exosome  meiotic spindle  
Pathways : KEGGPhagosome    Gap junction    Pathogenic Escherichia coli infection   
NDEx NetworkTUBB8
Atlas of Cancer Signalling NetworkTUBB8
Wikipedia pathwaysTUBB8
Orthology - Evolution
OrthoDB347688
GeneTree (enSembl)ENSG00000261456
Phylogenetic Trees/Animal Genes : TreeFamTUBB8
HOVERGENQ3ZCM7
HOGENOMQ3ZCM7
Homologs : HomoloGeneTUBB8
Homology/Alignments : Family Browser (UCSC)TUBB8
Gene fusions - Rearrangements
Tumor Fusion PortalTUBB8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUBB8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUBB8
dbVarTUBB8
ClinVarTUBB8
1000_GenomesTUBB8 
Exome Variant ServerTUBB8
ExAC (Exome Aggregation Consortium)ENSG00000261456
GNOMAD BrowserENSG00000261456
Genetic variants : HAPMAP347688
Genomic Variants (DGV)TUBB8 [DGVbeta]
DECIPHERTUBB8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUBB8 
Mutations
ICGC Data PortalTUBB8 
TCGA Data PortalTUBB8 
Broad Tumor PortalTUBB8
OASIS PortalTUBB8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUBB8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUBB8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUBB8
DgiDB (Drug Gene Interaction Database)TUBB8
DoCM (Curated mutations)TUBB8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUBB8 (select a term)
intoGenTUBB8
Cancer3DTUBB8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616768    616780   
Orphanet
DisGeNETTUBB8
MedgenTUBB8
Genetic Testing Registry TUBB8
NextProtQ3ZCM7 [Medical]
TSGene347688
GENETestsTUBB8
Target ValidationTUBB8
Huge Navigator TUBB8 [HugePedia]
snp3D : Map Gene to Disease347688
BioCentury BCIQTUBB8
ClinGenTUBB8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD347688
Chemical/Pharm GKB GenePA166048953
Clinical trialTUBB8
Miscellaneous
canSAR (ICR)TUBB8 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUBB8
EVEXTUBB8
GoPubMedTUBB8
iHOPTUBB8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:22:45 CET 2017

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