TUBGCP4 (tubulin gamma complex associated protein 4)

2014-11-01  

Identity

HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
76P,GCP-4,GCP4,Grip76,MCCRP3
FUSION GENES

Other Information

Locus ID:

NCBI: 27229
MIM: 609610
HGNC: 16691
Ensembl: ENSG00000137822

Variants:

dbSNP: 27229
ClinVar: 27229
TCGA: ENSG00000137822
COSMIC: TUBGCP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137822ENST00000260383Q9UGJ1
ENSG00000137822ENST00000561691H3BPU4
ENSG00000137822ENST00000563147H3BNL9
ENSG00000137822ENST00000563412H3BQY4
ENSG00000137822ENST00000563517H3BN56
ENSG00000137822ENST00000564079Q9UGJ1
ENSG00000137822ENST00000565548H3BS59
ENSG00000137822ENST00000566251H3BQ12

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Recruitment of NuMA to mitotic centrosomesREACTOMER-HSA-380320

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
205089832011Centrosome-related genes, genetic variation, and risk of breast cancer.16
258170182015Mutations in TUBGCP4 alter microtubule organization via the γ-tubulin ring complex in autosomal-recessive microcephaly with chorioretinopathy.13

Citation

Dessen P

TUBGCP4 (tubulin gamma complex associated protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75373/tubgcp4