TUBGCP5 (tubulin gamma complex associated protein 5)

2014-11-01  

Identity

HGNC
LOCATION
15q11.2
LOCUSID
ALIAS
GCP5
FUSION GENES

Other Information

Locus ID:

NCBI: 114791
MIM: 608147
HGNC: 18600
Ensembl: ENSG00000275835

Variants:

dbSNP: 114791
ClinVar: 114791
TCGA: ENSG00000275835
COSMIC: TUBGCP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000275835ENST00000610294A0A087X006
ENSG00000275835ENST00000612085A0A087WVL9
ENSG00000275835ENST00000614508A0A087X1Z1
ENSG00000275835ENST00000615383Q96RT8
ENSG00000275835ENST00000620435Q96RT8
ENSG00000275835ENST00000622507A0A087WVZ8

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Recruitment of NuMA to mitotic centrosomesREACTOMER-HSA-380320

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
145087082003Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.62
169828062006Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader-Willi syndrome.44
183163692008GSK-3beta regulates proper mitotic spindle formation in cooperation with a component of the gamma-tubulin ring complex, GCP5.24

Citation

Dessen P

TUBGCP5 (tubulin gamma complex associated protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75374/tubgcp5