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TUFM (Tu translation elongation factor, mitochondrial)

Identity

Alias_symbol (synonym)EFTu
EF-TuMT
EFTU
Other aliasCOXPD4
P43
HGNC (Hugo) TUFM
LocusID (NCBI) 7284
Atlas_Id 53287
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 28842411 and ends at 28846408 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUFM   12420
Cards
Entrez_Gene (NCBI)TUFM  7284  Tu translation elongation factor, mitochondrial
AliasesCOXPD4; EF-TuMT; EFTU; P43
GeneCards (Weizmann)TUFM
Ensembl hg19 (Hinxton)ENSG00000178952 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178952 [Gene_View]  chr16:28842411-28846408 [Contig_View]  TUFM [Vega]
ICGC DataPortalENSG00000178952
TCGA cBioPortalTUFM
AceView (NCBI)TUFM
Genatlas (Paris)TUFM
WikiGenes7284
SOURCE (Princeton)TUFM
Genetics Home Reference (NIH)TUFM
Genomic and cartography
GoldenPath hg38 (UCSC)TUFM  -     chr16:28842411-28846408 -  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUFM  -     16p11.2   [Description]    (hg19-Feb_2009)
EnsemblTUFM - 16p11.2 [CytoView hg19]  TUFM - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBITUFM [Mapview hg19]  TUFM [Mapview hg38]
OMIM602389   610678   
Gene and transcription
Genbank (Entrez)BC001633 BC010041 CA420396 HQ448224 L38995
RefSeq transcript (Entrez)NM_003321
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUFM
Cluster EST : UnigeneHs.12084 [ NCBI ]
CGAP (NCI)Hs.12084
Alternative Splicing GalleryENSG00000178952
Gene ExpressionTUFM [ NCBI-GEO ]   TUFM [ EBI - ARRAY_EXPRESS ]   TUFM [ SEEK ]   TUFM [ MEM ]
Gene Expression Viewer (FireBrowse)TUFM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7284
GTEX Portal (Tissue expression)TUFM
Human Protein AtlasENSG00000178952-TUFM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49411   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49411  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49411
Splice isoforms : SwissVarP49411
PhosPhoSitePlusP49411
Domaine pattern : Prosite (Expaxy)G_TR_1 (PS00301)    G_TR_2 (PS51722)   
Domains : Interpro (EBI)EFTu-like_2    EFTU_2    G_TR_CS    P-loop_NTPase    TF_GTP-bd_dom    Transl_B-barrel    Transl_elong_EF1A/Init_IF2_C    Transl_elong_EFTu/EF1A_bac/org    Transl_elong_EFTu/EF1A_C   
Domain families : Pfam (Sanger)GTP_EFTU_D2 (PF03144)    GTP_EFTU_D3 (PF03143)   
Domain families : Pfam (NCBI)pfam03144    pfam03143   
Conserved Domain (NCBI)TUFM
DMDM Disease mutations7284
Blocks (Seattle)TUFM
SuperfamilyP49411
Human Protein Atlas [tissue]ENSG00000178952-TUFM [tissue]
Peptide AtlasP49411
HPRD03861
IPIIPI00027107   
Protein Interaction databases
DIP (DOE-UCLA)P49411
IntAct (EBI)P49411
FunCoupENSG00000178952
BioGRIDTUFM
STRING (EMBL)TUFM
ZODIACTUFM
Ontologies - Pathways
QuickGOP49411
Ontology : AmiGORNA binding  translation elongation factor activity  GTPase activity  protein binding  GTP binding  mitochondrion  mitochondrial inner membrane  translational elongation  membrane  mitochondrial nucleoid  myelin sheath  response to ethanol  extracellular exosome  
Ontology : EGO-EBIRNA binding  translation elongation factor activity  GTPase activity  protein binding  GTP binding  mitochondrion  mitochondrial inner membrane  translational elongation  membrane  mitochondrial nucleoid  myelin sheath  response to ethanol  extracellular exosome  
NDEx NetworkTUFM
Atlas of Cancer Signalling NetworkTUFM
Wikipedia pathwaysTUFM
Orthology - Evolution
OrthoDB7284
GeneTree (enSembl)ENSG00000178952
Phylogenetic Trees/Animal Genes : TreeFamTUFM
HOVERGENP49411
HOGENOMP49411
Homologs : HomoloGeneTUFM
Homology/Alignments : Family Browser (UCSC)TUFM
Gene fusions - Rearrangements
Tumor Fusion PortalTUFM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUFM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUFM
dbVarTUFM
ClinVarTUFM
1000_GenomesTUFM 
Exome Variant ServerTUFM
ExAC (Exome Aggregation Consortium)ENSG00000178952
GNOMAD BrowserENSG00000178952
Genetic variants : HAPMAP7284
Genomic Variants (DGV)TUFM [DGVbeta]
DECIPHERTUFM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUFM 
Mutations
ICGC Data PortalTUFM 
TCGA Data PortalTUFM 
Broad Tumor PortalTUFM
OASIS PortalTUFM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUFM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUFM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TUFM
DgiDB (Drug Gene Interaction Database)TUFM
DoCM (Curated mutations)TUFM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUFM (select a term)
intoGenTUFM
Cancer3DTUFM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602389    610678   
Orphanet19802   
DisGeNETTUFM
MedgenTUFM
Genetic Testing Registry TUFM
NextProtP49411 [Medical]
TSGene7284
GENETestsTUFM
Target ValidationTUFM
Huge Navigator TUFM [HugePedia]
snp3D : Map Gene to Disease7284
BioCentury BCIQTUFM
ClinGenTUFM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7284
Chemical/Pharm GKB GenePA37082
Clinical trialTUFM
Miscellaneous
canSAR (ICR)TUFM (select the gene name)
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUFM
EVEXTUFM
GoPubMedTUFM
iHOPTUFM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:40:13 CET 2017

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