TUFT1 (tuftelin 1)

2017-10-01  

Identity

HGNC
TUFT1
LOCATION
1q21.3
LOCUSID
7286
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7286
MIM: 600087
HGNC: 12422
Ensembl: ENSG00000143367

Variants:

dbSNP: 7286
ClinVar: 7286
TCGA: ENSG00000143367
COSMIC: TUFT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143367ENST00000353024Q6UWW7
ENSG00000143367ENST00000368848Q9NNX1
ENSG00000143367ENST00000368849Q9NNX1
ENSG00000143367ENST00000392712A6PVU8

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
187810682008Enamel formation genes are associated with high caries experience in Turkish children.41
187810682008Enamel formation genes are associated with high caries experience in Turkish children.41
237905032013Genes expressed in dental enamel development are associated with molar-incisor hypomineralization.21
302503002019Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway.14
253736992015Effects of enamel matrix genes on dental caries are moderated by fluoride exposures.12
275663982016TUFT1 regulates metastasis of pancreatic cancer through HIF1-Snail pathway induced epithelial-mesenchymal transition.12
124891942002The human tuftelin gene and the expression of tuftelin in mineralizing and nonmineralizing tissues.10
117331432001The human tuftelin gene: cloning and characterization.5
284104282017TUFT1, a novel candidate gene for metatarsophalangeal osteoarthritis, plays a role in chondrogenesis on a calcium-related pathway.3

Citation

Dessen P

TUFT1 (tuftelin 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57112/tuft1