TUG1 (taurine up-regulated 1)

2013-11-01  

Identity

HGNC
TUG1
LOCATION
22q12.2
LOCUSID
55000
ALIAS
LINC00080,NCRNA00080,TI-227H
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55000
MIM: 614971
HGNC: 26066
Ensembl: ENSG00000253352

Variants:

dbSNP: 55000
ClinVar: 55000
TCGA: ENSG00000253352
COSMIC: TUG1

RNA/Proteins

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
220788782011ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs.251
248534212014P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression.163
157970182005The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina.158
269755292016Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer.85
263368702015Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2.72
237251332013Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis.70
273395532016TUG1: a pivotal oncogenic long non-coding RNA of human cancers.68
253661382015Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma.63
263188602015Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells.61
269136012016Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of p57.60

Citation

Dessen P

TUG1 (taurine up-regulated 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53567/tug1