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TUSC5 (tumor suppressor candidate 5)

Identity

Alias_symbol (synonym)LOST1
IFITMD3
Other aliasDSPB1
HGNC (Hugo) TUSC5
LocusID (NCBI) 286753
Atlas_Id 42898
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 1182957 and ends at 1204281 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CAND1 (12q14.3) / TUSC5 (17p13.3)TUSC5 (17p13.3) / CRK (17p13.3)CAND1 12q14.3 / TUSC5 17p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TUSC5   29592
Cards
Entrez_Gene (NCBI)TUSC5  286753  tumor suppressor candidate 5
AliasesDSPB1; IFITMD3; LOST1
GeneCards (Weizmann)TUSC5
Ensembl hg19 (Hinxton)ENSG00000184811 [Gene_View]  chr17:1182957-1204281 [Contig_View]  TUSC5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000184811 [Gene_View]  chr17:1182957-1204281 [Contig_View]  TUSC5 [Vega]
ICGC DataPortalENSG00000184811
TCGA cBioPortalTUSC5
AceView (NCBI)TUSC5
Genatlas (Paris)TUSC5
WikiGenes286753
SOURCE (Princeton)TUSC5
Genetics Home Reference (NIH)TUSC5
Genomic and cartography
GoldenPath hg19 (UCSC)TUSC5  -     chr17:1182957-1204281 +  17p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TUSC5  -     17p13.3   [Description]    (hg38-Dec_2013)
EnsemblTUSC5 - 17p13.3 [CytoView hg19]  TUSC5 - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBITUSC5 [Mapview hg19]  TUSC5 [Mapview hg38]
OMIM612211   
Gene and transcription
Genbank (Entrez)AB090231 AL831929 BC142615
RefSeq transcript (Entrez)NM_172367
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NT_187613 NW_004929405
Consensus coding sequences : CCDS (NCBI)TUSC5
Cluster EST : UnigeneHs.146059 [ NCBI ]
CGAP (NCI)Hs.146059
Alternative Splicing GalleryENSG00000184811
Gene ExpressionTUSC5 [ NCBI-GEO ]   TUSC5 [ EBI - ARRAY_EXPRESS ]   TUSC5 [ SEEK ]   TUSC5 [ MEM ]
Gene Expression Viewer (FireBrowse)TUSC5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286753
GTEX Portal (Tissue expression)TUSC5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXB3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IXB3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IXB3
Splice isoforms : SwissVarQ8IXB3
PhosPhoSitePlusQ8IXB3
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)TUSC5
DMDM Disease mutations286753
Blocks (Seattle)TUSC5
SuperfamilyQ8IXB3
Human Protein AtlasENSG00000184811
Peptide AtlasQ8IXB3
HPRD18248
IPIIPI00217491   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXB3
IntAct (EBI)Q8IXB3
FunCoupENSG00000184811
BioGRIDTUSC5
STRING (EMBL)TUSC5
ZODIACTUSC5
Ontologies - Pathways
QuickGOQ8IXB3
Ontology : AmiGOresponse to biotic stimulus  integral component of membrane  
Ontology : EGO-EBIresponse to biotic stimulus  integral component of membrane  
NDEx NetworkTUSC5
Atlas of Cancer Signalling NetworkTUSC5
Wikipedia pathwaysTUSC5
Orthology - Evolution
OrthoDB286753
GeneTree (enSembl)ENSG00000184811
Phylogenetic Trees/Animal Genes : TreeFamTUSC5
HOVERGENQ8IXB3
HOGENOMQ8IXB3
Homologs : HomoloGeneTUSC5
Homology/Alignments : Family Browser (UCSC)TUSC5
Gene fusions - Rearrangements
Fusion : MitelmanCAND1/TUSC5 [12q14.3/17p13.3]  [t(12;17)(q14;p13)]  
Fusion: TCGACAND1 12q14.3 TUSC5 17p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUSC5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUSC5
dbVarTUSC5
ClinVarTUSC5
1000_GenomesTUSC5 
Exome Variant ServerTUSC5
ExAC (Exome Aggregation Consortium)TUSC5 (select the gene name)
Genetic variants : HAPMAP286753
Genomic Variants (DGV)TUSC5 [DGVbeta]
DECIPHER (Syndromes)17:1182957-1204281  ENSG00000184811
CONAN: Copy Number AnalysisTUSC5 
Mutations
ICGC Data PortalTUSC5 
TCGA Data PortalTUSC5 
Broad Tumor PortalTUSC5
OASIS PortalTUSC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUSC5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUSC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUSC5
DgiDB (Drug Gene Interaction Database)TUSC5
DoCM (Curated mutations)TUSC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUSC5 (select a term)
intoGenTUSC5
Cancer3DTUSC5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612211   
Orphanet
MedgenTUSC5
Genetic Testing Registry TUSC5
NextProtQ8IXB3 [Medical]
TSGene286753
GENETestsTUSC5
Huge Navigator TUSC5 [HugePedia]
snp3D : Map Gene to Disease286753
BioCentury BCIQTUSC5
ClinGenTUSC5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286753
Chemical/Pharm GKB GenePA134868023
Clinical trialTUSC5
Miscellaneous
canSAR (ICR)TUSC5 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUSC5
EVEXTUSC5
GoPubMedTUSC5
iHOPTUSC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:32:50 CET 2017

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