Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific)

Identity

Alias_namesRBM21
RNA binding motif protein 21
Alias_symbol (synonym)FLJ22347
FLJ22267
FLJ21850
PAPD2
TUTase
Other aliasSTARPAP
URLC6
HGNC (Hugo) TUT1
LocusID (NCBI) 64852
Atlas_Id 55133
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62575045 and ends at 62591637 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		TUT1 (11q12.3) / BSCL2 (11q12.3)TUT1 (11q12.3) / SZT2 (1p34.2)TUT1 11q12.3 / BSCL2 11q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TUT1   26184
Cards
Entrez_Gene (NCBI)TUT1  64852  terminal uridylyl transferase 1, U6 snRNA-specific
AliasesPAPD2; RBM21; STARPAP; TUTase; 
URLC6
GeneCards (Weizmann)TUT1
Ensembl hg19 (Hinxton)ENSG00000149016 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149016 [Gene_View]  chr11:62575045-62591637 [Contig_View]  TUT1 [Vega]
ICGC DataPortalENSG00000149016
TCGA cBioPortalTUT1
AceView (NCBI)TUT1
Genatlas (Paris)TUT1
WikiGenes64852
SOURCE (Princeton)TUT1
Genetics Home Reference (NIH)TUT1
Genomic and cartography
GoldenPath hg38 (UCSC)TUT1  -     chr11:62575045-62591637 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TUT1  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblTUT1 - 11q12.3 [CytoView hg19]  TUT1 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBITUT1 [Mapview hg19]  TUT1 [Mapview hg38]
OMIM610641   
Gene and transcription
Genbank (Entrez)AB101208 AK025920 AK026000 AK292610 BC005013
RefSeq transcript (Entrez)NM_022830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TUT1
Cluster EST : UnigeneHs.728983 [ NCBI ]
CGAP (NCI)Hs.728983
Alternative Splicing GalleryENSG00000149016
Gene ExpressionTUT1 [ NCBI-GEO ]   TUT1 [ EBI - ARRAY_EXPRESS ]   TUT1 [ SEEK ]   TUT1 [ MEM ]
Gene Expression Viewer (FireBrowse)TUT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64852
GTEX Portal (Tissue expression)TUT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6E5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H6E5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H6E5
Splice isoforms : SwissVarQ9H6E5
Catalytic activity : Enzyme2.7.7.19 [ Enzyme-Expasy ]   2.7.7.192.7.7.19 [ IntEnz-EBI ]   2.7.7.19 [ BRENDA ]   2.7.7.19 [ KEGG ]   
PhosPhoSitePlusQ9H6E5
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    PAP_assoc    RRM_dom   
Domain families : Pfam (Sanger)PAP_assoc (PF03828)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam03828    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)TUT1
DMDM Disease mutations64852
Blocks (Seattle)TUT1
PDB (SRS)2E5G   
PDB (PDBSum)2E5G   
PDB (IMB)2E5G   
PDB (RSDB)2E5G   
Structural Biology KnowledgeBase2E5G   
SCOP (Structural Classification of Proteins)2E5G   
CATH (Classification of proteins structures)2E5G   
SuperfamilyQ9H6E5
Human Protein AtlasENSG00000149016
Peptide AtlasQ9H6E5
HPRD15226
IPIIPI01012096   IPI00946813   IPI00946648   IPI00010212   
Protein Interaction databases
DIP (DOE-UCLA)Q9H6E5
IntAct (EBI)Q9H6E5
FunCoupENSG00000149016
BioGRIDTUT1
STRING (EMBL)TUT1
ZODIACTUT1
Ontologies - Pathways
QuickGOQ9H6E5
Ontology : AmiGORNA binding  mRNA 3'-UTR binding  polynucleotide adenylyltransferase activity  protein binding  ATP binding  nucleus  nucleolus  cytosol  mRNA cleavage and polyadenylation specificity factor complex  mRNA polyadenylation  mRNA polyadenylation  snRNA processing  nuclear speck  enzyme binding  metal ion binding  RNA uridylyltransferase activity  histone mRNA catabolic process  pre-mRNA cleavage required for polyadenylation  
Ontology : EGO-EBIRNA binding  mRNA 3'-UTR binding  polynucleotide adenylyltransferase activity  protein binding  ATP binding  nucleus  nucleolus  cytosol  mRNA cleavage and polyadenylation specificity factor complex  mRNA polyadenylation  mRNA polyadenylation  snRNA processing  nuclear speck  enzyme binding  metal ion binding  RNA uridylyltransferase activity  histone mRNA catabolic process  pre-mRNA cleavage required for polyadenylation  
NDEx NetworkTUT1
Atlas of Cancer Signalling NetworkTUT1
Wikipedia pathwaysTUT1
Orthology - Evolution
OrthoDB64852
GeneTree (enSembl)ENSG00000149016
Phylogenetic Trees/Animal Genes : TreeFamTUT1
HOVERGENQ9H6E5
HOGENOMQ9H6E5
Homologs : HomoloGeneTUT1
Homology/Alignments : Family Browser (UCSC)TUT1
Gene fusions - Rearrangements
Fusion : MitelmanTUT1/BSCL2 [11q12.3/11q12.3]  
Fusion: TCGATUT1 11q12.3 BSCL2 11q12.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTUT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TUT1
dbVarTUT1
ClinVarTUT1
1000_GenomesTUT1 
Exome Variant ServerTUT1
ExAC (Exome Aggregation Consortium)TUT1 (select the gene name)
Genetic variants : HAPMAP64852
Genomic Variants (DGV)TUT1 [DGVbeta]
DECIPHERTUT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTUT1 
Mutations
ICGC Data PortalTUT1 
TCGA Data PortalTUT1 
Broad Tumor PortalTUT1
OASIS PortalTUT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTUT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TUT1
DgiDB (Drug Gene Interaction Database)TUT1
DoCM (Curated mutations)TUT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TUT1 (select a term)
intoGenTUT1
Cancer3DTUT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610641   
Orphanet
MedgenTUT1
Genetic Testing Registry TUT1
NextProtQ9H6E5 [Medical]
TSGene64852
GENETestsTUT1
Target ValidationTUT1
Huge Navigator TUT1 [HugePedia]
snp3D : Map Gene to Disease64852
BioCentury BCIQTUT1
ClinGenTUT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64852
Chemical/Pharm GKB GenePA162407405
Clinical trialTUT1
Miscellaneous
canSAR (ICR)TUT1 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTUT1
EVEXTUT1
GoPubMedTUT1
iHOPTUT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 13:01:24 CEST 2017
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