TUT7 (terminal uridylyl transferase 7)

2018-11-01  

Identity

HGNC
TUT7
LOCATION
9q21.33
LOCUSID
79670
ALIAS
PAPD6,TENT3B,ZCCHC6

Other Information

Locus ID:

NCBI: 79670
MIM: 613467
HGNC: 25817
Ensembl: ENSG00000083223

Variants:

dbSNP: 79670
ClinVar: 79670
TCGA: ENSG00000083223
COSMIC: TUT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000083223ENST00000277141X6R3Q3
ENSG00000083223ENST00000375947Q5VYS9
ENSG00000083223ENST00000375948Q5VYT0
ENSG00000083223ENST00000375957A0A0C4DFW3
ENSG00000083223ENST00000375960Q5VYS8
ENSG00000083223ENST00000375963Q5VYS8

References

Pubmed IDYearTitleCitations
230636542012Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.124
228989842012Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).89
254802992014Uridylation by TUT4 and TUT7 marks mRNA for degradation.79
259798282015TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.34
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.17
286716662017Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.15
276099022016TUT7 catalyzes the uridylation of the 3' end for rapid degradation of histone mRNA.13
301223512018Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s.10
3117835320193' Uridylation Confers miRNAs with Non-canonical Target Repertoires.4
286659392017The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.3

Citation

Dessen P

TUT7 (terminal uridylyl transferase 7)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80343/tut7