TXNDC15 (thioredoxin domain containing 15)

2014-08-01  

Identity

HGNC
TXNDC15
LOCATION
5q31.1
LOCUSID
79770
ALIAS
BUG,C5orf14,UNQ335
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79770
MIM: 617778
HGNC: 20652
Ensembl: ENSG00000113621

Variants:

dbSNP: 79770
ClinVar: 79770
TCGA: ENSG00000113621
COSMIC: TXNDC15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113621ENST00000358387Q96J42
ENSG00000113621ENST00000506916D6RBD9
ENSG00000113621ENST00000507024D6RAV9
ENSG00000113621ENST00000508779H0Y997
ENSG00000113621ENST00000508810D6RB48
ENSG00000113621ENST00000509954H0Y928
ENSG00000113621ENST00000511070D6R962

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
216420082011Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione.4
308510852019A prenatally diagnosed case of Meckel-Gruber syndrome with novel compound heterozygous pathogenic variants in the TXNDC15 gene.1

Citation

Dessen P

TXNDC15 (thioredoxin domain containing 15)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54742/txndc15