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TXNIP (thioredoxin interacting protein)

Identity

Other namesEST01027
HHCPA78
THIF
VDUP1
HGNC (Hugo) TXNIP
LocusID (NCBI) 10628
Location 1q21.1
Location_base_pair Starts at 145438462 and ends at 145442628 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TXNIP   16952
Entrez_Gene (NCBI)TXNIP  10628  thioredoxin interacting protein
Cards
GeneCards (Weizmann)TXNIP
Ensembl (Hinxton)ENSG00000117289 [Gene_View]  chr1:145438462-145442628 [Contig_View]  TXNIP [Vega]
AceView (NCBI)TXNIP
Genatlas (Paris)TXNIP
SOURCE (Stanford)NM_006472
Genomic and cartography
GoldenPath (UCSC)TXNIP  -  1q21.1   chr1:145438462-145442628 +  1q21.1   [Description]    (hg19-Feb_2009)
EnsemblTXNIP - 1q21.1 [CytoView]
Mapping of homologs : NCBITXNIP [Mapview]
OMIM606599   
Gene and transcription
Genbank (Entrez)AK226090 AK301148 AK301203 AK304670 AY594328
RefSeq transcript (SRS)NM_006472
RefSeq transcript (Entrez)NM_006472
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NT_167185 NW_001838504 NW_003871055 NW_004077999
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NT_167185 NW_001838504 NW_003871055 NW_004077999
Consensus coding sequences : CCDS (NCBI)TXNIP
Cluster EST : UnigeneHs.533977 [ SRS ] Hs.533977 [ NCBI ]
CGAP (NCI)Hs.533977
Alternative Splicing : Fast-db (Paris)GSHG0000892
Alternative Splicing GalleryENSG00000117289
Gene ExpressionTXNIP [ NCBI-GEO ]   TXNIP [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3M7 (SRS) Q9H3M7 (Uniprot)
NextProtQ9H3M7
With graphics : InterProQ9H3M7
Splice isoforms : SwissVarQ9H3M7(Swissvar)
Domains : Interpro (SRS)Arrestin-like_N    Arrestin_C-like    Ig_E-set   
Domains : Interpro (EBI)Arrestin-like_N    Arrestin_C-like    Ig_E-set   
Related proteins : CluSTrQ9H3M7
Domain families : Pfam (SRS)Arrestin_C (PF02752)    Arrestin_N (PF00339)   
Domain families : Pfam (Sanger)Arrestin_C (PF02752)    Arrestin_N (PF00339)   
Domain families : Pfam (NCBI)pfam02752    pfam00339   
Domain families : Smart (EMBL)Arrestin_C (SM01017)  
DMDM10628
Blocks (Seattle)Q9H3M7
Human Protein AtlasENSG00000117289
HPRD05964
IPIIPI00007956   IPI00909604   IPI00514375   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3M7
IntAct (EBI)Q9H3M7
FunCoupENSG00000117289
REACTOMETXNIP
Protein Interaction Database10628
BioGRIDTXNIP
InParanoidQ9H3M7
Interologous Interaction database Q9H3M7
IntegromeDBTXNIP
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TXNIP
SNP (GeneSNP Utah)TXNIP
SNP : HGBaseTXNIP
Genetic variants : HAPMAPTXNIP
Somatic Mutations in Cancer : COSMICTXNIP 
CONAN: Copy Number AnalysisTXNIP 
Mutations and Diseases : HGMDTXNIP
OMIM606599   
GENETests606599   
Disease Genetic AssociationTXNIP
Huge Navigator TXNIP [HugePedia]  TXNIP [HugeCancerGEM]
Genomic VariantsTXNIP  TXNIP [DGVbeta]
snp3D : Map Gene to Disease10628
General knowledge
Homologs : HomoloGeneTXNIP
Homology/Alignments : Family Browser (UCSC)TXNIP
Phylogenetic Trees/Animal Genes : TreeFamTXNIP
Chemical/Protein Interactions : CTD10628
Chemical/Pharm GKB GenePA38194
Clinical trialTXNIP
Cancer Resource (Charite)ENSG00000117289
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  enzyme inhibitor activity  protein binding  nucleus  cytoplasm  mitochondrial intermembrane space  cytosol  transcription, DNA-dependent  protein import into nucleus  cell cycle  response to mechanical stimulus  response to glucose stimulus  keratinocyte differentiation  ubiquitin protein ligase binding  response to estradiol stimulus  response to progesterone stimulus  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  regulation of cell proliferation  response to drug  response to hydrogen peroxide  positive regulation of apoptotic process  innate immune response  platelet-derived growth factor receptor signaling pathway  response to calcium ion  negative regulation of cell division  cellular response to tumor cell  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  enzyme inhibitor activity  protein binding  nucleus  cytoplasm  mitochondrial intermembrane space  cytosol  transcription, DNA-dependent  protein import into nucleus  cell cycle  response to mechanical stimulus  response to glucose stimulus  keratinocyte differentiation  ubiquitin protein ligase binding  response to estradiol stimulus  response to progesterone stimulus  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  regulation of cell proliferation  response to drug  response to hydrogen peroxide  positive regulation of apoptotic process  innate immune response  platelet-derived growth factor receptor signaling pathway  response to calcium ion  negative regulation of cell division  cellular response to tumor cell  
Other databases
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
PubGeneTXNIP
iHOPTXNIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:32:42 CEST 2013
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