Identity
HGNC
LOCATION
1q21.1
LOCUSID
ALIAS
ARRDC6,EST01027,HHCPA78,THIF,VDUP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10628
MIM: 606599
HGNC: 16952
Ensembl: ENSG00000265972
Variants:
dbSNP: 10628
ClinVar: 10628
TCGA: ENSG00000265972
COSMIC: TXNIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000265972 | ENST00000425134 | Q9H3M7 |
| ENSG00000265972 | ENST00000582401 | Q9H3M7 |
| ENSG00000265972 | ENST00000582401 | A0A024R4B7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37594665 | 2024 | METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression. | 1 |
| 37632267 | 2024 | Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration. | 0 |
| 37735933 | 2024 | Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein. | 0 |
| 37890873 | 2024 | A novel link between melatonin and circ_0005753/PTBP1/TXNIP regulatory network in the modulation of osteogenic potential in mesenchymal stem cells. | 0 |
| 38054509 | 2024 | Amino acid deprivation induces TXNIP expression by NRF2 downregulation. | 0 |
| 38118268 | 2024 | Knockdown of TXNIP alleviates gestational diabetes mellitus by activating autophagy to regulate cell proliferation and apoptosis in high glucose-treated trophoblasts. | 0 |
| 38169654 | 2024 | TXNIP in liver sinusoidal endothelial cells ameliorates alcohol-associated liver disease via nitric oxide production. | 1 |
| 38411328 | 2024 | KLF4 interacts with TXNIP to modulate the pyroptosis in ulcerative colitis via regulating NLRP3 signaling. | 0 |
| 38538307 | 2024 | Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study. | 0 |
| 38616177 | 2024 | TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease. | 0 |
| 37594665 | 2024 | METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression. | 1 |
| 37632267 | 2024 | Advanced glycation end products induce nucleus pulposus cell apoptosis by upregulating TXNIP via inhibiting glycolysis pathway in intervertebral disc degeneration. | 0 |
| 37735933 | 2024 | Serum carotenoid levels are positively associated with DNA methylation of thioredoxin-interacting protein. | 0 |
| 37890873 | 2024 | A novel link between melatonin and circ_0005753/PTBP1/TXNIP regulatory network in the modulation of osteogenic potential in mesenchymal stem cells. | 0 |
| 38054509 | 2024 | Amino acid deprivation induces TXNIP expression by NRF2 downregulation. | 0 |
Citation
Dessen P
TXNIP (thioredoxin interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46111/txnip
