Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TXNL1 (thioredoxin like 1)

Identity

Alias_names32kD
TXNL
Alias_symbol (synonym)Txl
TRP32
Other aliasHEL-S-114
TXL-1
HGNC (Hugo) TXNL1
LocusID (NCBI) 9352
Atlas_Id 52491
Location 18q21.31  [Link to chromosome band 18q21]
Location_base_pair Starts at 54270053 and ends at 54305920 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NEAT1 (11q13.1) / TXNL1 (18q21.31)OAZ1 (19p13.3) / TXNL1 (18q21.31)TXNL1 (18q21.31) / LRP1B (2q22.1)
TXNL1 18q21.31 / LRP1B 2q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TXNL1   12436
Cards
Entrez_Gene (NCBI)TXNL1  9352  thioredoxin like 1
AliasesHEL-S-114; TRP32; TXL-1; TXNL; 
Txl
GeneCards (Weizmann)TXNL1
Ensembl hg19 (Hinxton)ENSG00000091164 [Gene_View]  chr18:54270053-54305920 [Contig_View]  TXNL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000091164 [Gene_View]  chr18:54270053-54305920 [Contig_View]  TXNL1 [Vega]
ICGC DataPortalENSG00000091164
TCGA cBioPortalTXNL1
AceView (NCBI)TXNL1
Genatlas (Paris)TXNL1
WikiGenes9352
SOURCE (Princeton)TXNL1
Genetics Home Reference (NIH)TXNL1
Genomic and cartography
GoldenPath hg19 (UCSC)TXNL1  -     chr18:54270053-54305920 -  18q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TXNL1  -     18q21.31   [Description]    (hg38-Dec_2013)
EnsemblTXNL1 - 18q21.31 [CytoView hg19]  TXNL1 - 18q21.31 [CytoView hg38]
Mapping of homologs : NCBITXNL1 [Mapview hg19]  TXNL1 [Mapview hg38]
OMIM603049   
Gene and transcription
Genbank (Entrez)AB209263 AF003938 AF051896 AF052659 AK094926
RefSeq transcript (Entrez)NM_004786
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929411
Consensus coding sequences : CCDS (NCBI)TXNL1
Cluster EST : UnigeneHs.114412 [ NCBI ]
CGAP (NCI)Hs.114412
Alternative Splicing GalleryENSG00000091164
Gene ExpressionTXNL1 [ NCBI-GEO ]   TXNL1 [ EBI - ARRAY_EXPRESS ]   TXNL1 [ SEEK ]   TXNL1 [ MEM ]
Gene Expression Viewer (FireBrowse)TXNL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9352
GTEX Portal (Tissue expression)TXNL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43396   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43396  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43396
Splice isoforms : SwissVarO43396
PhosPhoSitePlusO43396
Domaine pattern : Prosite (Expaxy)PITH (PS51532)    THIOREDOXIN_1 (PS00194)   
Domains : Interpro (EBI)Galactose-bd-like    PITH_dom    Thioredoxin    Thioredoxin-like_fold    Thioredoxin_CS    Thioredoxin_domain   
Domain families : Pfam (Sanger)PITH (PF06201)    Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam06201    pfam00085   
Conserved Domain (NCBI)TXNL1
DMDM Disease mutations9352
Blocks (Seattle)TXNL1
PDB (SRS)1GH2    1WWY   
PDB (PDBSum)1GH2    1WWY   
PDB (IMB)1GH2    1WWY   
PDB (RSDB)1GH2    1WWY   
Structural Biology KnowledgeBase1GH2    1WWY   
SCOP (Structural Classification of Proteins)1GH2    1WWY   
CATH (Classification of proteins structures)1GH2    1WWY   
SuperfamilyO43396
Human Protein AtlasENSG00000091164
Peptide AtlasO43396
HPRD04335
IPIIPI00305692   IPI01016016   
Protein Interaction databases
DIP (DOE-UCLA)O43396
IntAct (EBI)O43396
FunCoupENSG00000091164
BioGRIDTXNL1
STRING (EMBL)TXNL1
ZODIACTXNL1
Ontologies - Pathways
QuickGOO43396
Ontology : AmiGOsulfate assimilation  proteasome complex  nucleus  cytoplasm  mitochondrion  protein folding  glycerol ether metabolic process  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  cellular response to oxidative stress  cell redox homeostasis  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBIsulfate assimilation  proteasome complex  nucleus  cytoplasm  mitochondrion  protein folding  glycerol ether metabolic process  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  cellular response to oxidative stress  cell redox homeostasis  oxidation-reduction process  extracellular exosome  
NDEx NetworkTXNL1
Atlas of Cancer Signalling NetworkTXNL1
Wikipedia pathwaysTXNL1
Orthology - Evolution
OrthoDB9352
GeneTree (enSembl)ENSG00000091164
Phylogenetic Trees/Animal Genes : TreeFamTXNL1
HOVERGENO43396
HOGENOMO43396
Homologs : HomoloGeneTXNL1
Homology/Alignments : Family Browser (UCSC)TXNL1
Gene fusions - Rearrangements
Fusion : MitelmanTXNL1/LRP1B [18q21.31/2q22.1]  
Fusion: TCGATXNL1 18q21.31 LRP1B 2q22.1 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTXNL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TXNL1
dbVarTXNL1
ClinVarTXNL1
1000_GenomesTXNL1 
Exome Variant ServerTXNL1
ExAC (Exome Aggregation Consortium)TXNL1 (select the gene name)
Genetic variants : HAPMAP9352
Genomic Variants (DGV)TXNL1 [DGVbeta]
DECIPHER (Syndromes)18:54270053-54305920  ENSG00000091164
CONAN: Copy Number AnalysisTXNL1 
Mutations
ICGC Data PortalTXNL1 
TCGA Data PortalTXNL1 
Broad Tumor PortalTXNL1
OASIS PortalTXNL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTXNL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTXNL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TXNL1
DgiDB (Drug Gene Interaction Database)TXNL1
DoCM (Curated mutations)TXNL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TXNL1 (select a term)
intoGenTXNL1
Cancer3DTXNL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603049   
Orphanet
MedgenTXNL1
Genetic Testing Registry TXNL1
NextProtO43396 [Medical]
TSGene9352
GENETestsTXNL1
Huge Navigator TXNL1 [HugePedia]
snp3D : Map Gene to Disease9352
BioCentury BCIQTXNL1
ClinGenTXNL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9352
Chemical/Pharm GKB GenePA134967488
Clinical trialTXNL1
Miscellaneous
canSAR (ICR)TXNL1 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTXNL1
EVEXTXNL1
GoPubMedTXNL1
iHOPTXNL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:32:55 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.