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TXNL4A (thioredoxin like 4A)

Identity

Alias_namesTXNL4
thioredoxin-like 4
thioredoxin-like 4A
Alias_symbol (synonym)U5-15kD
DIM1
HsT161
DIB1
SNRNP15
Other aliasBMKS
HGNC (Hugo) TXNL4A
LocusID (NCBI) 10907
Atlas_Id 42735
Location 18q23  [Link to chromosome band 18q23]
Location_base_pair Starts at 79972867 and ends at 79988592 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GCN1 (12q24.23) / TXNL4A (18q23)NF1 (17q11.2) / TXNL4A (18q23)YTHDC1 (4q13.2) / TXNL4A (18q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TXNL4A   30551
Cards
Entrez_Gene (NCBI)TXNL4A  10907  thioredoxin like 4A
AliasesBMKS; DIB1; DIM1; SNRNP15; 
TXNL4; U5-15kD
GeneCards (Weizmann)TXNL4A
Ensembl hg19 (Hinxton)ENSG00000141759 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000141759 [Gene_View]  chr18:79972867-79988592 [Contig_View]  TXNL4A [Vega]
ICGC DataPortalENSG00000141759
TCGA cBioPortalTXNL4A
AceView (NCBI)TXNL4A
Genatlas (Paris)TXNL4A
WikiGenes10907
SOURCE (Princeton)TXNL4A
Genetics Home Reference (NIH)TXNL4A
Genomic and cartography
GoldenPath hg38 (UCSC)TXNL4A  -     chr18:79972867-79988592 -  18q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TXNL4A  -     18q23   [Description]    (hg19-Feb_2009)
EnsemblTXNL4A - 18q23 [CytoView hg19]  TXNL4A - 18q23 [CytoView hg38]
Mapping of homologs : NCBITXNL4A [Mapview hg19]  TXNL4A [Mapview hg38]
OMIM608572   611595   
Gene and transcription
Genbank (Entrez)AA923682 AF023611 AF023612 AF146373 AK308703
RefSeq transcript (Entrez)NM_001303471 NM_001305557 NM_001305563 NM_001305564 NM_006701
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TXNL4A
Cluster EST : UnigeneHs.465498 [ NCBI ]
CGAP (NCI)Hs.465498
Alternative Splicing GalleryENSG00000141759
Gene ExpressionTXNL4A [ NCBI-GEO ]   TXNL4A [ EBI - ARRAY_EXPRESS ]   TXNL4A [ SEEK ]   TXNL4A [ MEM ]
Gene Expression Viewer (FireBrowse)TXNL4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10907
GTEX Portal (Tissue expression)TXNL4A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP83876   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP83876  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP83876
Splice isoforms : SwissVarP83876
PhosPhoSitePlusP83876
Domains : Interpro (EBI)Dim1    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)DIM1 (PF02966)   
Domain families : Pfam (NCBI)pfam02966   
Domain families : Smart (EMBL)DIM1 (SM01410)  
Conserved Domain (NCBI)TXNL4A
DMDM Disease mutations10907
Blocks (Seattle)TXNL4A
PDB (SRS)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
PDB (PDBSum)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
PDB (IMB)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
PDB (RSDB)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
Structural Biology KnowledgeBase1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
SCOP (Structural Classification of Proteins)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
CATH (Classification of proteins structures)1PQN    1QGV    1SYX    3JCR    4BWQ    4BWS    4CDO   
SuperfamilyP83876
Human Protein AtlasENSG00000141759
Peptide AtlasP83876
HPRD18252
IPIIPI00216338   IPI00384845   
Protein Interaction databases
DIP (DOE-UCLA)P83876
IntAct (EBI)P83876
FunCoupENSG00000141759
BioGRIDTXNL4A
STRING (EMBL)TXNL4A
ZODIACTXNL4A
Ontologies - Pathways
QuickGOP83876
Ontology : AmiGOspliceosomal complex assembly  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  spliceosomal complex  U5 snRNP  cytosol  cell cycle  nuclear membrane  U4/U6 x U5 tri-snRNP complex  cell division  
Ontology : EGO-EBIspliceosomal complex assembly  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  spliceosomal complex  U5 snRNP  cytosol  cell cycle  nuclear membrane  U4/U6 x U5 tri-snRNP complex  cell division  
Pathways : KEGGSpliceosome   
NDEx NetworkTXNL4A
Atlas of Cancer Signalling NetworkTXNL4A
Wikipedia pathwaysTXNL4A
Orthology - Evolution
OrthoDB10907
GeneTree (enSembl)ENSG00000141759
Phylogenetic Trees/Animal Genes : TreeFamTXNL4A
HOVERGENP83876
HOGENOMP83876
Homologs : HomoloGeneTXNL4A
Homology/Alignments : Family Browser (UCSC)TXNL4A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTXNL4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TXNL4A
dbVarTXNL4A
ClinVarTXNL4A
1000_GenomesTXNL4A 
Exome Variant ServerTXNL4A
ExAC (Exome Aggregation Consortium)TXNL4A (select the gene name)
Genetic variants : HAPMAP10907
Genomic Variants (DGV)TXNL4A [DGVbeta]
DECIPHERTXNL4A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTXNL4A 
Mutations
ICGC Data PortalTXNL4A 
TCGA Data PortalTXNL4A 
Broad Tumor PortalTXNL4A
OASIS PortalTXNL4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTXNL4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTXNL4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TXNL4A
DgiDB (Drug Gene Interaction Database)TXNL4A
DoCM (Curated mutations)TXNL4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TXNL4A (select a term)
intoGenTXNL4A
Cancer3DTXNL4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608572    611595   
Orphanet1451   
MedgenTXNL4A
Genetic Testing Registry TXNL4A
NextProtP83876 [Medical]
TSGene10907
GENETestsTXNL4A
Target ValidationTXNL4A
Huge Navigator TXNL4A [HugePedia]
snp3D : Map Gene to Disease10907
BioCentury BCIQTXNL4A
ClinGenTXNL4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10907
Chemical/Pharm GKB GenePA134937290
Clinical trialTXNL4A
Miscellaneous
canSAR (ICR)TXNL4A (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTXNL4A
EVEXTXNL4A
GoPubMedTXNL4A
iHOPTXNL4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:01:28 CEST 2017

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