Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TXNL4B (thioredoxin-like 4B)

Identity

Alias_namesthioredoxin-like 4B
Alias_symbol (synonym)FLJ20511
DLP
Dim2
Other alias
HGNC (Hugo) TXNL4B
LocusID (NCBI) 54957
Atlas_Id 75391
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 72118756 and ends at 72127768 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
G6PC (17q21.31) / TXNL4B (16q22.2)SAA2-SAA4 (11p15.1) / TXNL4B (16q22.2)SNX17 (2p23.3) / TXNL4B (16q22.2)
TXNL4B (16q22.2) / ALB (4q13.3)TXNL4B (16q22.2) / ALDOB (9q31.1)TXNL4B (16q22.2) / CFB (6p21.33)
TXNL4B (16q22.2) / MRPS10 (6p21.1)TXNL4B (16q22.2) / NR4A1 (12q13.13)TXNL4B (16q22.2) / SLC22A3 (6q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TXNL4B   26041
Cards
Entrez_Gene (NCBI)TXNL4B  54957  thioredoxin-like 4B
AliasesDLP; Dim2
GeneCards (Weizmann)TXNL4B
Ensembl hg19 (Hinxton)ENSG00000140830 [Gene_View]  chr16:72118756-72127768 [Contig_View]  TXNL4B [Vega]
Ensembl hg38 (Hinxton)ENSG00000140830 [Gene_View]  chr16:72118756-72127768 [Contig_View]  TXNL4B [Vega]
ICGC DataPortalENSG00000140830
TCGA cBioPortalTXNL4B
AceView (NCBI)TXNL4B
Genatlas (Paris)TXNL4B
WikiGenes54957
SOURCE (Princeton)TXNL4B
Genetics Home Reference (NIH)TXNL4B
Genomic and cartography
GoldenPath hg19 (UCSC)TXNL4B  -     chr16:72118756-72127768 -  16q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TXNL4B  -     16q22.2   [Description]    (hg38-Dec_2013)
EnsemblTXNL4B - 16q22.2 [CytoView hg19]  TXNL4B - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBITXNL4B [Mapview hg19]  TXNL4B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK000518 AK222889 AK308891 AY566808 BC009646
RefSeq transcript (Entrez)NM_001142317 NM_001142318 NM_017853
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)TXNL4B
Cluster EST : UnigeneHs.134406 [ NCBI ]
CGAP (NCI)Hs.134406
Alternative Splicing GalleryENSG00000140830
Gene ExpressionTXNL4B [ NCBI-GEO ]   TXNL4B [ EBI - ARRAY_EXPRESS ]   TXNL4B [ SEEK ]   TXNL4B [ MEM ]
Gene Expression Viewer (FireBrowse)TXNL4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54957
GTEX Portal (Tissue expression)TXNL4B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NX01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NX01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NX01
Splice isoforms : SwissVarQ9NX01
PhosPhoSitePlusQ9NX01
Domains : Interpro (EBI)mRNA_splic_U5    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)DIM1 (PF02966)   
Domain families : Pfam (NCBI)pfam02966   
Conserved Domain (NCBI)TXNL4B
DMDM Disease mutations54957
Blocks (Seattle)TXNL4B
PDB (SRS)1XBS    3GIX    4IN0   
PDB (PDBSum)1XBS    3GIX    4IN0   
PDB (IMB)1XBS    3GIX    4IN0   
PDB (RSDB)1XBS    3GIX    4IN0   
Structural Biology KnowledgeBase1XBS    3GIX    4IN0   
SCOP (Structural Classification of Proteins)1XBS    3GIX    4IN0   
CATH (Classification of proteins structures)1XBS    3GIX    4IN0   
SuperfamilyQ9NX01
Human Protein AtlasENSG00000140830
Peptide AtlasQ9NX01
HPRD11655
IPIIPI00016481   
Protein Interaction databases
DIP (DOE-UCLA)Q9NX01
IntAct (EBI)Q9NX01
FunCoupENSG00000140830
BioGRIDTXNL4B
STRING (EMBL)TXNL4B
ZODIACTXNL4B
Ontologies - Pathways
QuickGOQ9NX01
Ontology : AmiGOspliceosomal complex assembly  protein binding  spliceosomal complex  U5 snRNP  mitotic nuclear division  U4/U6 x U5 tri-snRNP complex  
Ontology : EGO-EBIspliceosomal complex assembly  protein binding  spliceosomal complex  U5 snRNP  mitotic nuclear division  U4/U6 x U5 tri-snRNP complex  
NDEx NetworkTXNL4B
Atlas of Cancer Signalling NetworkTXNL4B
Wikipedia pathwaysTXNL4B
Orthology - Evolution
OrthoDB54957
GeneTree (enSembl)ENSG00000140830
Phylogenetic Trees/Animal Genes : TreeFamTXNL4B
HOVERGENQ9NX01
HOGENOMQ9NX01
Homologs : HomoloGeneTXNL4B
Homology/Alignments : Family Browser (UCSC)TXNL4B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTXNL4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TXNL4B
dbVarTXNL4B
ClinVarTXNL4B
1000_GenomesTXNL4B 
Exome Variant ServerTXNL4B
ExAC (Exome Aggregation Consortium)TXNL4B (select the gene name)
Genetic variants : HAPMAP54957
Genomic Variants (DGV)TXNL4B [DGVbeta]
DECIPHER (Syndromes)16:72118756-72127768  ENSG00000140830
CONAN: Copy Number AnalysisTXNL4B 
Mutations
ICGC Data PortalTXNL4B 
TCGA Data PortalTXNL4B 
Broad Tumor PortalTXNL4B
OASIS PortalTXNL4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTXNL4B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTXNL4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TXNL4B
DgiDB (Drug Gene Interaction Database)TXNL4B
DoCM (Curated mutations)TXNL4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TXNL4B (select a term)
intoGenTXNL4B
Cancer3DTXNL4B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTXNL4B
Genetic Testing Registry TXNL4B
NextProtQ9NX01 [Medical]
TSGene54957
GENETestsTXNL4B
Huge Navigator TXNL4B [HugePedia]
snp3D : Map Gene to Disease54957
BioCentury BCIQTXNL4B
ClinGenTXNL4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54957
Chemical/Pharm GKB GenePA134944912
Clinical trialTXNL4B
Miscellaneous
canSAR (ICR)TXNL4B (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTXNL4B
EVEXTXNL4B
GoPubMedTXNL4B
iHOPTXNL4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:50:31 CET 2017

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