| Nomenclature | | HGNC (Hugo) | TYRP1 12450 |
| Entrez_Gene (NCBI) | TYRP1 7306 tyrosinase-related protein 1 |
| Cards | | GeneCards (Weizmann) | TYRP1 |
| Ensembl (Hinxton) | ENSG00000107165 [Gene_View] chr9:12693386-12710266 [Contig_View] TYRP1 [Vega] |
| AceView (NCBI) | TYRP1 |
| Genatlas (Paris) | TYRP1 |
| SOURCE (Stanford) | NM_000550 |
| Genomic and cartography | | GoldenPath (UCSC) | TYRP1 - 9p23 chr9:12693386-12710266 + 9p23 [Description] (hg19-Feb_2009) |
| Ensembl | TYRP1 - 9p23 [CytoView] |
| Mapping of homologs : NCBI | TYRP1 [Mapview] |
| OMIM | 115501 203290 612271 |
| Gene and transcription |
| Genbank (Entrez) | AK297887 AL600654 BC052608 CD679533 CR407683 |
| RefSeq transcript (SRS) | NM_000550 |
| RefSeq transcript (Entrez) | NM_000550 |
| RefSeq genomic (SRS) | AC_000141 NC_000009 NC_018920 NG_011705 NT_008413 NW_001839149 NW_004078038 |
| RefSeq genomic (Entrez) | AC_000141 NC_000009 NC_018920 NG_011705 NT_008413 NW_001839149 NW_004078038 |
| Consensus coding sequences : CCDS (NCBI) | TYRP1 |
| Cluster EST : Unigene | Hs.270279 [ SRS ] Hs.270279 [ NCBI ] |
| CGAP (NCI) | Hs.270279 |
| Alternative Splicing : Fast-db (Paris) | GSHG0030019 |
| Alternative Splicing Gallery | ENSG00000107165 |
| Gene Expression | TYRP1 [ NCBI-GEO ] TYRP1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P17643 (SRS) P17643 (Uniprot) |
| NextProt | P17643 |
| With graphics : InterPro | P17643 |
| Splice isoforms : SwissVar | P17643(Swissvar) |
| Domaine pattern : Prosite (SRS) | TYROSINASE_1 (PS00497) TYROSINASE_2 (PS00498) |
| Domaine pattern : Prosite (Expaxy) | TYROSINASE_1 (PS00497) TYROSINASE_2 (PS00498) |
| Domains : Interpro (SRS) | DiOHindole_carboxylic_A_Oxase Tyrosinase Unchr_di-copper_centre |
| Domains : Interpro (EBI) | DiOHindole_carboxylic_A_Oxase Tyrosinase Unchr_di-copper_centre |
| Related proteins : CluSTr | P17643 |
| Domain families : Pfam (SRS) | Tyrosinase (PF00264) |
| Domain families : Pfam (Sanger) | Tyrosinase (PF00264) |
| Domain families : Pfam (NCBI) | pfam00264 |
| DMDM | 7306 |
| Blocks (Seattle) | P17643 |
| Human Protein Atlas | ENSG00000107165 |
| HPRD | 00283 |
| IPI | IPI00015913 IPI00930372 IPI00479738 IPI00947481 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P17643 |
| IntAct (EBI) | P17643 |
| FunCoup | ENSG00000107165 |
| REACTOME | TYRP1 |
| Protein Interaction Database | 7306 |
| BioGRID | TYRP1 |
| InParanoid | P17643 |
| Interologous Interaction database | P17643 |
| IntegromeDB | TYRP1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | TYRP1 |
| SNP (GeneSNP Utah) | TYRP1 |
| SNP : HGBase | TYRP1 |
| Genetic variants : HAPMAP | TYRP1 |
| Somatic Mutations in Cancer : COSMIC | TYRP1 |
| CONAN: Copy Number Analysis | TYRP1 |
| Mutations and Diseases : HGMD | TYRP1 |
| OMIM | 115501 203290 612271 |
| GENETests | 115501 203290 612271 |
| Disease Genetic Association | TYRP1 |
| Huge Navigator |
TYRP1 [HugePedia] TYRP1 [HugeCancerGEM] |
| Genomic Variants | TYRP1 TYRP1 [DGVbeta] |
| snp3D : Map Gene to Disease | 7306 |
| General knowledge |
|---|
| Homologs : HomoloGene | TYRP1 |
| Homology/Alignments : Family Browser (UCSC) | TYRP1 |
| Phylogenetic Trees/Animal Genes : TreeFam | TYRP1 |
| Catalytic activity : Enzyme | 1.14.18.- [ Enzyme-Expasy ] 1.14.18.- [ Enzyme-SRS ] 1.14.18.- [ IntEnz-EBI ] 1.14.18.- [ BRENDA ] 1.14.18.- [ KEGG ] |
| Chemical/Protein Interactions : CTD | 7306 |
| Chemical/Pharm GKB Gene | PA37101 |
| Clinical trial | TYRP1 |
| Cancer Resource (Charite) | ENSG00000107165 |
| Ontology : AmiGO | copper ion binding protein binding endosome membrane integral to membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen melanocyte differentiation clathrin-coated endocytic vesicle membrane melanosome organization melanosome membrane melanin biosynthetic process melanosome protein homodimerization activity acetoacetic acid metabolic process protein heterodimerization activity |
| Ontology : EGO-EBI | copper ion binding protein binding endosome membrane integral to membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen melanocyte differentiation clathrin-coated endocytic vesicle membrane melanosome organization melanosome membrane melanin biosynthetic process melanosome protein homodimerization activity acetoacetic acid metabolic process protein heterodimerization activity |
| Pathways : KEGG | Tyrosine metabolism |
| Other databases | | Probes |
|---|
| Litterature | | PubMed | 67 Pubmed reference(s) in Entrez |
| PubGene | TYRP1 |
| iHOP | TYRP1 |
