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U2AF1 (U2 small nuclear RNA auxiliary factor 1)

Identity

Other namesFP793
RN
RNU2AF1
U2AF35
U2AFBP
HGNC (Hugo) U2AF1
LocusID (NCBI) 7307
Location 21q22.3
Location_base_pair Starts at 44513066 and ends at 44527688 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)U2AF1   12453
Cards
Entrez_Gene (NCBI)U2AF1  7307  U2 small nuclear RNA auxiliary factor 1
GeneCards (Weizmann)U2AF1
Ensembl (Hinxton)ENSG00000160201 [Gene_View]  chr21:44513066-44527688 [Contig_View]  U2AF1 [Vega]
ICGC DataPortalENSG00000160201
AceView (NCBI)U2AF1
Genatlas (Paris)U2AF1
WikiGenes7307
SOURCE (Princeton)NM_001025203 NM_001025204 NM_006758
Genomic and cartography
GoldenPath (UCSC)U2AF1  -  21q22.3   chr21:44513066-44527688 -  21q22.3   [Description]    (hg19-Feb_2009)
EnsemblU2AF1 - 21q22.3 [CytoView]
Mapping of homologs : NCBIU2AF1 [Mapview]
OMIM191317   
Gene and transcription
Genbank (Entrez)AB451244 AF370386 AJ627978 AK022152 AK023589
RefSeq transcript (Entrez)NM_001025203 NM_001025204 NM_006758
RefSeq genomic (Entrez)AC_000153 NC_000021 NG_029455 NT_011512 NW_001838715
Consensus coding sequences : CCDS (NCBI)U2AF1
Cluster EST : UnigeneHs.365116 [ NCBI ]
CGAP (NCI)Hs.365116
Alternative Splicing : Fast-db (Paris)GSHG0019739
Alternative Splicing GalleryENSG00000160201
Gene ExpressionU2AF1 [ NCBI-GEO ]     U2AF1 [ SEEK ]   U2AF1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01081 (Uniprot)
NextProtQ01081  [Medical]
With graphics : InterProQ01081
Splice isoforms : SwissVarQ01081 (Swissvar)
Domaine pattern : Prosite (Expaxy)RRM (PS50102)    ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom    U2_small    Znf_CCCH   
Related proteins : CluSTrQ01081
Domain families : Pfam (Sanger)zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00642   
Domain families : Smart (EMBL)RRM (SM00360)  ZnF_C3H1 (SM00356)  
DMDM Disease mutations7307
Blocks (Seattle)Q01081
PDB (SRS)1JMT   
PDB (PDBSum)1JMT   
PDB (IMB)1JMT   
PDB (RSDB)1JMT   
Human Protein AtlasENSG00000160201
Peptide AtlasQ01081
HPRD01871
IPIIPI00005613   IPI00917123   IPI00619914   IPI00946935   IPI00619942   
Protein Interaction databases
DIP (DOE-UCLA)Q01081
IntAct (EBI)Q01081
FunCoupENSG00000160201
BioGRIDU2AF1
IntegromeDBU2AF1
STRING (EMBL)U2AF1
Ontologies - Pathways
QuickGOQ01081
Ontology : AmiGOnucleotide binding  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  spliceosomal complex  nucleolus  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  mRNA processing  mRNA export from nucleus  RNA splicing  gene expression  Cajal body  nuclear speck  mRNA 3'-end processing  poly(A) RNA binding  metal ion binding  RS domain binding  catalytic step 2 spliceosome  
Ontology : EGO-EBInucleotide binding  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  spliceosomal complex  nucleolus  transcription from RNA polymerase II promoter  termination of RNA polymerase II transcription  mRNA processing  mRNA export from nucleus  RNA splicing  gene expression  Cajal body  nuclear speck  mRNA 3'-end processing  poly(A) RNA binding  metal ion binding  RS domain binding  catalytic step 2 spliceosome  
Pathways : BIOCARTASpliceosomal Assembly [Genes]   
Pathways : KEGGSpliceosome    Shigellosis   
Protein Interaction DatabaseU2AF1
Wikipedia pathwaysU2AF1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)U2AF1
SNP (GeneSNP Utah)U2AF1
SNP : HGBaseU2AF1
Genetic variants : HAPMAPU2AF1
1000_GenomesU2AF1 
ICGC programENSG00000160201 
Cancer Gene: CensusU2AF1 
CONAN: Copy Number AnalysisU2AF1 
Somatic Mutations in Cancer : COSMICU2AF1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)21:44513066-44527688
Mutations and Diseases : HGMDU2AF1
OMIM191317   
MedgenU2AF1
GENETestsU2AF1
Disease Genetic AssociationU2AF1
Huge Navigator U2AF1 [HugePedia]  U2AF1 [HugeCancerGEM]
Genomic VariantsU2AF1  U2AF1 [DGVbeta]
Exome VariantU2AF1
dbVarU2AF1
ClinVarU2AF1
snp3D : Map Gene to Disease7307
General knowledge
Homologs : HomoloGeneU2AF1
Homology/Alignments : Family Browser (UCSC)U2AF1
Phylogenetic Trees/Animal Genes : TreeFamU2AF1
Chemical/Protein Interactions : CTD7307
Chemical/Pharm GKB GenePA37103
Clinical trialU2AF1
Cancer Resource (Charite)ENSG00000160201
Other databases
Probes
Litterature
PubMed92 Pubmed reference(s) in Entrez
CoreMineU2AF1
GoPubMedU2AF1
iHOPU2AF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:04:05 CET 2014

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