U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4)

2014-11-01  

Identity

HGNC
LOCATION
19q13.12
LOCUSID
ALIAS
U2AF1-RS3,U2AF1L3,U2AF1L3V1,U2AF1RS3,U2af26

Other Information

Locus ID:

NCBI: 199746
MIM: 601080
HGNC: 23020
Ensembl: ENSG00000161265

Variants:

dbSNP: 199746
ClinVar: 199746
TCGA: ENSG00000161265
COSMIC: U2AF1L4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161265ENST00000292879Q8WU68
ENSG00000161265ENST00000378975Q8WU68
ENSG00000161265ENST00000412391Q8WU68
ENSG00000161265ENST00000587886A0A1D5RMU4
ENSG00000161265ENST00000587987K7EJH3
ENSG00000161265ENST00000589429S4R353
ENSG00000161265ENST00000591057K7EJM7
ENSG00000161265ENST00000591084S4R443
ENSG00000161265ENST00000594792M0R1E1
ENSG00000161265ENST00000600296S4R3L8
ENSG00000161265ENST00000601236M0QYK5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
ShigellosisKEGGhsa05131
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232466982013Human PSENEN and U2AF1L4 genes are concertedly regulated by a genuine bidirectional promoter.6
184604682008Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26.3
220229692011Functional dissection of an enhancer-like element located within the second intron of the human U2AF1L4 gene.0
271433772016[Cytokine-mediated regulation of expression of Gfi1 and U2afll4 genes activated by T-cells with different differentiation status in vitro].0

Citation

Dessen P

U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75399/u2af1l4