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UBAC2 (UBA domain containing 2)

Identity

Alias_namesPHGDHL1
phosphoglycerate dehydrogenase like 1
Alias_symbol (synonym)FLJ30548
RP11-178C10.1
Other alias
HGNC (Hugo) UBAC2
LocusID (NCBI) 337867
Atlas_Id 75406
Location 13q32.3  [Link to chromosome band 13q32]
Location_base_pair Starts at 99200425 and ends at 99386499 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CD74 (5q32) / UBAC2 (13q32.3)PHGDH (1p12) / UBAC2 (13q32.3)UBAC2 (13q32.3) / IDH3B (20p13)
UBAC2 (13q32.3) / SPTB (14q23.3)UBAC2 (13q32.3) / UBAC2 (13q32.3)WAC (10p12.1) / UBAC2 (13q32.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBAC2   20486
Cards
Entrez_Gene (NCBI)UBAC2  337867  UBA domain containing 2
AliasesPHGDHL1
GeneCards (Weizmann)UBAC2
Ensembl hg19 (Hinxton)ENSG00000134882 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134882 [Gene_View]  chr13:99200425-99386499 [Contig_View]  UBAC2 [Vega]
ICGC DataPortalENSG00000134882
TCGA cBioPortalUBAC2
AceView (NCBI)UBAC2
Genatlas (Paris)UBAC2
WikiGenes337867
SOURCE (Princeton)UBAC2
Genetics Home Reference (NIH)UBAC2
Genomic and cartography
GoldenPath hg38 (UCSC)UBAC2  -     chr13:99200425-99386499 +  13q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBAC2  -     13q32.3   [Description]    (hg19-Feb_2009)
EnsemblUBAC2 - 13q32.3 [CytoView hg19]  UBAC2 - 13q32.3 [CytoView hg38]
Mapping of homologs : NCBIUBAC2 [Mapview hg19]  UBAC2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF339812 AI866141 AK054563 AK055110 AK075419
RefSeq transcript (Entrez)NM_001144072 NM_177967
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBAC2
Cluster EST : UnigeneHs.508545 [ NCBI ]
CGAP (NCI)Hs.508545
Alternative Splicing GalleryENSG00000134882
Gene ExpressionUBAC2 [ NCBI-GEO ]   UBAC2 [ EBI - ARRAY_EXPRESS ]   UBAC2 [ SEEK ]   UBAC2 [ MEM ]
Gene Expression Viewer (FireBrowse)UBAC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)337867
GTEX Portal (Tissue expression)UBAC2
Human Protein AtlasENSG00000134882-UBAC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBM4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBM4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBM4
Splice isoforms : SwissVarQ8NBM4
PhosPhoSitePlusQ8NBM4
Domaine pattern : Prosite (Expaxy)UBA (PS50030)   
Domains : Interpro (EBI)UBA    UBA-like   
Domain families : Pfam (Sanger)UBA (PF00627)   
Domain families : Pfam (NCBI)pfam00627   
Domain families : Smart (EMBL)UBA (SM00165)  
Conserved Domain (NCBI)UBAC2
DMDM Disease mutations337867
Blocks (Seattle)UBAC2
SuperfamilyQ8NBM4
Human Protein Atlas [tissue]ENSG00000134882-UBAC2 [tissue]
Peptide AtlasQ8NBM4
IPIIPI00168284   IPI00007034   IPI00829996   IPI00941744   IPI00829931   IPI00646359   IPI00514240   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBM4
IntAct (EBI)Q8NBM4
FunCoupENSG00000134882
BioGRIDUBAC2
STRING (EMBL)UBAC2
ZODIACUBAC2
Ontologies - Pathways
QuickGOQ8NBM4
Ontology : AmiGOserine-type endopeptidase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  proteolysis  integral component of membrane  ubiquitin binding  protein localization to endoplasmic reticulum  negative regulation of retrograde protein transport, ER to cytosol  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  proteolysis  integral component of membrane  ubiquitin binding  protein localization to endoplasmic reticulum  negative regulation of retrograde protein transport, ER to cytosol  
NDEx NetworkUBAC2
Atlas of Cancer Signalling NetworkUBAC2
Wikipedia pathwaysUBAC2
Orthology - Evolution
OrthoDB337867
GeneTree (enSembl)ENSG00000134882
Phylogenetic Trees/Animal Genes : TreeFamUBAC2
HOVERGENQ8NBM4
HOGENOMQ8NBM4
Homologs : HomoloGeneUBAC2
Homology/Alignments : Family Browser (UCSC)UBAC2
Gene fusions - Rearrangements
Tumor Fusion PortalUBAC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBAC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBAC2
dbVarUBAC2
ClinVarUBAC2
1000_GenomesUBAC2 
Exome Variant ServerUBAC2
ExAC (Exome Aggregation Consortium)ENSG00000134882
GNOMAD BrowserENSG00000134882
Genetic variants : HAPMAP337867
Genomic Variants (DGV)UBAC2 [DGVbeta]
DECIPHERUBAC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBAC2 
Mutations
ICGC Data PortalUBAC2 
TCGA Data PortalUBAC2 
Broad Tumor PortalUBAC2
OASIS PortalUBAC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBAC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBAC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBAC2
DgiDB (Drug Gene Interaction Database)UBAC2
DoCM (Curated mutations)UBAC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBAC2 (select a term)
intoGenUBAC2
Cancer3DUBAC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet703   
DisGeNETUBAC2
MedgenUBAC2
Genetic Testing Registry UBAC2
NextProtQ8NBM4 [Medical]
TSGene337867
GENETestsUBAC2
Target ValidationUBAC2
Huge Navigator UBAC2 [HugePedia]
snp3D : Map Gene to Disease337867
BioCentury BCIQUBAC2
ClinGenUBAC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD337867
Chemical/Pharm GKB GenePA162407839
Clinical trialUBAC2
Miscellaneous
canSAR (ICR)UBAC2 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBAC2
EVEXUBAC2
GoPubMedUBAC2
iHOPUBAC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:29:06 CET 2017

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