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UBASH3A (ubiquitin associated and SH3 domain containing A)

Identity

Alias_symbol (synonym)STS-2
TULA
CLIP4
Other aliasTULA-1
HGNC (Hugo) UBASH3A
LocusID (NCBI) 53347
Atlas_Id 75413
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 42403862 and ends at 42447680 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TCHP (12q24.11) / UBASH3A (21q22.3)TRAPPC10 (21q22.3) / UBASH3A (21q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBASH3A   12462
Cards
Entrez_Gene (NCBI)UBASH3A  53347  ubiquitin associated and SH3 domain containing A
AliasesCLIP4; STS-2; TULA; TULA-1
GeneCards (Weizmann)UBASH3A
Ensembl hg19 (Hinxton)ENSG00000160185 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160185 [Gene_View]  chr21:42403862-42447680 [Contig_View]  UBASH3A [Vega]
ICGC DataPortalENSG00000160185
TCGA cBioPortalUBASH3A
AceView (NCBI)UBASH3A
Genatlas (Paris)UBASH3A
WikiGenes53347
SOURCE (Princeton)UBASH3A
Genetics Home Reference (NIH)UBASH3A
Genomic and cartography
GoldenPath hg38 (UCSC)UBASH3A  -     chr21:42403862-42447680 +  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBASH3A  -     21q22.3   [Description]    (hg19-Feb_2009)
EnsemblUBASH3A - 21q22.3 [CytoView hg19]  UBASH3A - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBIUBASH3A [Mapview hg19]  UBASH3A [Mapview hg38]
OMIM605736   
Gene and transcription
Genbank (Entrez)AA707211 AF520809 AF521702 AJ277750 AK301279
RefSeq transcript (Entrez)NM_001001895 NM_001243467 NM_018961
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBASH3A
Cluster EST : UnigeneHs.473912 [ NCBI ]
CGAP (NCI)Hs.473912
Alternative Splicing GalleryENSG00000160185
Gene ExpressionUBASH3A [ NCBI-GEO ]   UBASH3A [ EBI - ARRAY_EXPRESS ]   UBASH3A [ SEEK ]   UBASH3A [ MEM ]
Gene Expression Viewer (FireBrowse)UBASH3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53347
GTEX Portal (Tissue expression)UBASH3A
Human Protein AtlasENSG00000160185-UBASH3A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP57075   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP57075  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP57075
Splice isoforms : SwissVarP57075
PhosPhoSitePlusP57075
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    UBA (PS50030)   
Domains : Interpro (EBI)cNuc_Pdiesterase    His_Pase_superF_clade-1    His_PPase_superfam    SH3_domain    UBA    UBA-like   
Domain families : Pfam (Sanger)His_Phos_1 (PF00300)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00300    pfam14604   
Domain families : Smart (EMBL)SH3 (SM00326)  
Conserved Domain (NCBI)UBASH3A
DMDM Disease mutations53347
Blocks (Seattle)UBASH3A
PDB (SRS)2CRN   
PDB (PDBSum)2CRN   
PDB (IMB)2CRN   
PDB (RSDB)2CRN   
Structural Biology KnowledgeBase2CRN   
SCOP (Structural Classification of Proteins)2CRN   
CATH (Classification of proteins structures)2CRN   
SuperfamilyP57075
Human Protein Atlas [tissue]ENSG00000160185-UBASH3A [tissue]
Peptide AtlasP57075
HPRD06904
IPIIPI00025707   IPI00215661   IPI00789382   
Protein Interaction databases
DIP (DOE-UCLA)P57075
IntAct (EBI)P57075
FunCoupENSG00000160185
BioGRIDUBASH3A
STRING (EMBL)UBASH3A
ZODIACUBASH3A
Ontologies - Pathways
QuickGOP57075
Ontology : AmiGOregulation of cytokine production  protein binding  nucleus  cytosol  negative regulation of T cell receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIregulation of cytokine production  protein binding  nucleus  cytosol  negative regulation of T cell receptor signaling pathway  extracellular exosome  
NDEx NetworkUBASH3A
Atlas of Cancer Signalling NetworkUBASH3A
Wikipedia pathwaysUBASH3A
Orthology - Evolution
OrthoDB53347
GeneTree (enSembl)ENSG00000160185
Phylogenetic Trees/Animal Genes : TreeFamUBASH3A
HOVERGENP57075
HOGENOMP57075
Homologs : HomoloGeneUBASH3A
Homology/Alignments : Family Browser (UCSC)UBASH3A
Gene fusions - Rearrangements
Tumor Fusion PortalUBASH3A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBASH3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBASH3A
dbVarUBASH3A
ClinVarUBASH3A
1000_GenomesUBASH3A 
Exome Variant ServerUBASH3A
ExAC (Exome Aggregation Consortium)ENSG00000160185
GNOMAD BrowserENSG00000160185
Genetic variants : HAPMAP53347
Genomic Variants (DGV)UBASH3A [DGVbeta]
DECIPHERUBASH3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBASH3A 
Mutations
ICGC Data PortalUBASH3A 
TCGA Data PortalUBASH3A 
Broad Tumor PortalUBASH3A
OASIS PortalUBASH3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBASH3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBASH3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBASH3A
DgiDB (Drug Gene Interaction Database)UBASH3A
DoCM (Curated mutations)UBASH3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBASH3A (select a term)
intoGenUBASH3A
Cancer3DUBASH3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605736   
Orphanet
DisGeNETUBASH3A
MedgenUBASH3A
Genetic Testing Registry UBASH3A
NextProtP57075 [Medical]
TSGene53347
GENETestsUBASH3A
Target ValidationUBASH3A
Huge Navigator UBASH3A [HugePedia]
snp3D : Map Gene to Disease53347
BioCentury BCIQUBASH3A
ClinGenUBASH3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53347
Chemical/Pharm GKB GenePA37112
Clinical trialUBASH3A
Miscellaneous
canSAR (ICR)UBASH3A (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBASH3A
EVEXUBASH3A
GoPubMedUBASH3A
iHOPUBASH3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:20:42 CET 2017

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