Atlas of Genetics and Cytogenetics in Oncology and Haematology

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UBE2A (ubiquitin-conjugating enzyme E2A)

Identity

Other namesHHR6A
MRXS30
MRXSN
RAD6A
UBC2
HGNC (Hugo) UBE2A
LocusID (NCBI) 7319
Location Xq24
Location_base_pair Starts at 118708499 and ends at 118718379 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UBE2A   12472
Entrez_Gene (NCBI)UBE2A  7319  ubiquitin-conjugating enzyme E2A
Cards
GeneCards (Weizmann)UBE2A
Ensembl (Hinxton)ENSG00000077721 [Gene_View]  chrX:118708499-118718379 [Contig_View]  UBE2A [Vega]
AceView (NCBI)UBE2A
Genatlas (Paris)UBE2A
SOURCE (Stanford)NM_003336 NM_181762 NM_181777
Genomic and cartography
GoldenPath (UCSC)UBE2A  -  Xq24   chrX:118708499-118718379 +  Xq24   [Description]    (hg19-Feb_2009)
EnsemblUBE2A - Xq24 [CytoView]
Mapping of homologs : NCBIUBE2A [Mapview]
OMIM300860   312180   
Gene and transcription
Genbank (Entrez)AK223045 AK223064 AK297696 AK301675 AK313092
RefSeq transcript (SRS)NM_003336 NM_181762 NM_181777
RefSeq transcript (Entrez)NM_003336 NM_181762 NM_181777
RefSeq genomic (SRS)AC_000155 NC_000023 NC_018934 NG_009267 NT_011786 NW_001842395 NW_004078125
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_009267 NT_011786 NW_001842395 NW_004078125
Consensus coding sequences : CCDS (NCBI)UBE2A
Cluster EST : UnigeneHs.379466 [ SRS ] Hs.379466 [ NCBI ]
CGAP (NCI)Hs.379466
Alternative Splicing : Fast-db (Paris)GSHG0031781
Alternative Splicing GalleryENSG00000077721
Gene ExpressionUBE2A [ NCBI-GEO ]   UBE2A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49459 (SRS) P49459 (Uniprot)
NextProtP49459
With graphics : InterProP49459
Splice isoforms : SwissVarP49459(Swissvar)
Domaine pattern : Prosite (SRS)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (SRS)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Related proteins : CluSTrP49459
Domain families : Pfam (SRS)UQ_con (PF00179)   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
DMDM7319
Blocks (Seattle)P49459
Human Protein AtlasENSG00000077721
HPRD02422
IPIIPI00746451   IPI00375549   IPI00843825   
Protein Interaction databases
DIP (DOE-UCLA)P49459
IntAct (EBI)P49459
FunCoupENSG00000077721
REACTOMEUBE2A
Protein Interaction Database7319
BioGRIDUBE2A
InParanoidP49459
Interologous Interaction database P49459
IntegromeDBUBE2A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)UBE2A
SNP (GeneSNP Utah)UBE2A
SNP : HGBaseUBE2A
Genetic variants : HAPMAPUBE2A
Somatic Mutations in Cancer : COSMICUBE2A 
CONAN: Copy Number AnalysisUBE2A 
Mutations and Diseases : HGMDUBE2A
OMIM300860    312180   
GENETests300860    312180   
Disease Genetic AssociationUBE2A
Huge Navigator UBE2A [HugePedia]  UBE2A [HugeCancerGEM]
Genomic VariantsUBE2A  UBE2A [DGVbeta]
snp3D : Map Gene to Disease7319
General knowledge
Homologs : HomoloGeneUBE2A
Homology/Alignments : Family Browser (UCSC)UBE2A
Phylogenetic Trees/Animal Genes : TreeFamUBE2A
Catalytic activity : Enzyme6.3.2.19 [ Enzyme-Expasy ]   6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   
Chemical/Protein Interactions : CTD7319
Chemical/Pharm GKB GenePA37122
Clinical trialUBE2A
Cancer Resource (Charite)ENSG00000077721
Ontology : AmiGOprotein polyubiquitination  chromatin  nuclear chromatin  in utero embryonic development  XY body  antigen processing and presentation of peptide antigen via MHC class I  ubiquitin-protein ligase activity  protein binding  ATP binding  cytosol  DNA repair  postreplication repair  ubiquitin-dependent protein catabolic process  positive regulation of cell proliferation  response to UV  ubiquitin protein ligase binding  HULC complex  histone H2A ubiquitination  protein autoubiquitination  maternal process involved in female pregnancy  protein K48-linked ubiquitination  protein K11-linked ubiquitination  
Ontology : EGO-EBIprotein polyubiquitination  chromatin  nuclear chromatin  in utero embryonic development  XY body  antigen processing and presentation of peptide antigen via MHC class I  ubiquitin-protein ligase activity  protein binding  ATP binding  cytosol  DNA repair  postreplication repair  ubiquitin-dependent protein catabolic process  positive regulation of cell proliferation  response to UV  ubiquitin protein ligase binding  HULC complex  histone H2A ubiquitination  protein autoubiquitination  maternal process involved in female pregnancy  protein K48-linked ubiquitination  protein K11-linked ubiquitination  
Other databases
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
PubGeneUBE2A
iHOPUBE2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:22:17 CEST 2013
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