UBE2B (ubiquitin-conjugating enzyme E2B (RAD6 homolog))

Identity

Other names	E2-17kDa
	HHR6B
	HR6B
	RAD6B
	UBC2
Hugo	UBE2B
Location	5q23-q31
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	UBE2B
GDB	UBE2B
Entrez_Gene	UBE2B  7320  ubiquitin-conjugating enzyme E2B (RAD6 homolog)
	Cards
GeneCards	UBE2B
Ensembl	UBE2B [Search_View]   ENSG00000119048 [Gene_View]
Genatlas	UBE2B
GeneLynx	UBE2B
eGenome	UBE2B
euGene	7320
	Genomic and cartography
GoldenPath	UBE2B  -     chr5:133734769-133755697 +  5q31.1   [Description]    (hg18-March_2006)
Ensembl	UBE2B - 5q31.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2B
	Gene and transcription
Genbank	BC001694 [ ENTREZ ]
Genbank	BC005979 [ ENTREZ ]
Genbank	BC008404 [ ENTREZ ]
Genbank	BC008470 [ ENTREZ ]
Genbank	BT007071 [ ENTREZ ]
RefSeq	NM_003337 [ SRS ]    NM_003337 [ ENTREZ ]
RefSeq	AC_000048 [ SRS ]    AC_000048 [ ENTREZ ]
RefSeq	NC_000005 [ SRS ]    NC_000005 [ ENTREZ ]
RefSeq	NT_034772 [ SRS ]    NT_034772 [ ENTREZ ]
RefSeq	NW_922784 [ SRS ]    NW_922784 [ ENTREZ ]
AceView	UBE2B AceView - NCBI
Unigene	Hs.695927 [ SRS ]    Hs.695927 [ NCBI ]     HS695927 [ spliceNest ]
Fast-db	9805 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P63146 [ SRS]    P63146 [ EXPASY ]     P63146 [ INTERPRO ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P63146
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P63146 UBE2B_HUMAN [ Domain structure ]   P63146 UBE2B_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P63146
PDB	1JAS [ SRS ]    1JAS [ PdbSum ],   1JAS [ IMB ]   1JAS [ RSDB ]
PDB	1NXA [ SRS ]    1NXA [ PdbSum ],   1NXA [ IMB ]   1NXA [ RSDB ]
HPRD	01533
	Protein Interaction databases
DIP	P63146
IntAct	P63146
	Polymorphism : SNP, mutations, diseases
OMIM	179095    [ map ]
GENECLINICS	179095
SNP	UBE2B [dbSNP-NCBI]
SNP	NM_003337 [SNP-NCI]
SNP	UBE2B [GeneSNPs - Utah]  UBE2B] [HGBASE - SRS]
HAPMAP	UBE2B [HAPMAP]
COSMIC	UBE2B [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2B
	General knowledge
Family Browser	UBE2B [UCSC Family Browser]
SOURCE	NM_003337
SMD	Hs.695927
SAGE	Hs.695927
Enzyme	6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ Brenda-SRS ]   6.3.2.19 [ KEGG ]   6.3.2.19 [ WIT ]
GO	chromatin [Amigo]  chromatin
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	plasma membrane [Amigo]  plasma membrane
GO	postreplication repair [Amigo]  postreplication repair
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	ubiquitin cycle [Amigo]  ubiquitin cycle
GO	sperm axoneme assembly [Amigo]  sperm axoneme assembly
GO	ligase activity [Amigo]  ligase activity
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
PubGene	UBE2B
TreeFam	UBE2B
CTD	7320 [Comparative Genomics Database]
	Other databases
	Probes
Probe	UBE2B Related clones (RZPD - Berlin)
	PubMed
PubMed	16 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:34:02 2008