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UBE2D4 (ubiquitin conjugating enzyme E2 D4 (putative))

Identity

Alias_namesubiquitin-conjugating enzyme E2D 4 (putative)
Alias_symbol (synonym)HBUCE1
Other alias
HGNC (Hugo) UBE2D4
LocusID (NCBI) 51619
Atlas_Id 46866
Location 7p13  [Link to chromosome band 7p13]
Location_base_pair Starts at 43926436 and ends at 43956136 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2D4   21647
Cards
Entrez_Gene (NCBI)UBE2D4  51619  ubiquitin conjugating enzyme E2 D4 (putative)
AliasesHBUCE1
GeneCards (Weizmann)UBE2D4
Ensembl hg19 (Hinxton)ENSG00000078967 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078967 [Gene_View]  chr7:43926436-43956136 [Contig_View]  UBE2D4 [Vega]
ICGC DataPortalENSG00000078967
TCGA cBioPortalUBE2D4
AceView (NCBI)UBE2D4
Genatlas (Paris)UBE2D4
WikiGenes51619
SOURCE (Princeton)UBE2D4
Genetics Home Reference (NIH)UBE2D4
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2D4  -     chr7:43926436-43956136 +  7p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2D4  -     7p13   [Description]    (hg19-Feb_2009)
EnsemblUBE2D4 - 7p13 [CytoView hg19]  UBE2D4 - 7p13 [CytoView hg38]
Mapping of homologs : NCBIUBE2D4 [Mapview hg19]  UBE2D4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF125044 AF125045 AK001446 AK056566 AW014299
RefSeq transcript (Entrez)NM_015983
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2D4
Cluster EST : UnigeneHs.19196 [ NCBI ]
CGAP (NCI)Hs.19196
Alternative Splicing GalleryENSG00000078967
Gene ExpressionUBE2D4 [ NCBI-GEO ]   UBE2D4 [ EBI - ARRAY_EXPRESS ]   UBE2D4 [ SEEK ]   UBE2D4 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2D4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51619
GTEX Portal (Tissue expression)UBE2D4
Human Protein AtlasENSG00000078967-UBE2D4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2X8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2X8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2X8
Splice isoforms : SwissVarQ9Y2X8
PhosPhoSitePlusQ9Y2X8
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2D4
DMDM Disease mutations51619
Blocks (Seattle)UBE2D4
SuperfamilyQ9Y2X8
Human Protein Atlas [tissue]ENSG00000078967-UBE2D4 [tissue]
Peptide AtlasQ9Y2X8
HPRD14242
IPIIPI00006475   IPI01010713   IPI00926616   IPI00925832   IPI00927099   IPI00926270   IPI00926051   IPI01012108   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2X8
IntAct (EBI)Q9Y2X8
FunCoupENSG00000078967
BioGRIDUBE2D4
STRING (EMBL)UBE2D4
ZODIACUBE2D4
Ontologies - Pathways
QuickGOQ9Y2X8
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  ATP binding  protein ubiquitination  protein K29-linked ubiquitination  protein K27-linked ubiquitination  ubiquitin conjugating enzyme activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  protein K11-linked ubiquitination  protein K6-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  ATP binding  protein ubiquitination  protein K29-linked ubiquitination  protein K27-linked ubiquitination  ubiquitin conjugating enzyme activity  protein K63-linked ubiquitination  protein K48-linked ubiquitination  protein K11-linked ubiquitination  protein K6-linked ubiquitination  
Pathways : KEGGUbiquitin mediated proteolysis    Protein processing in endoplasmic reticulum   
NDEx NetworkUBE2D4
Atlas of Cancer Signalling NetworkUBE2D4
Wikipedia pathwaysUBE2D4
Orthology - Evolution
OrthoDB51619
GeneTree (enSembl)ENSG00000078967
Phylogenetic Trees/Animal Genes : TreeFamUBE2D4
HOVERGENQ9Y2X8
HOGENOMQ9Y2X8
Homologs : HomoloGeneUBE2D4
Homology/Alignments : Family Browser (UCSC)UBE2D4
Gene fusions - Rearrangements
Tumor Fusion PortalUBE2D4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2D4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2D4
dbVarUBE2D4
ClinVarUBE2D4
1000_GenomesUBE2D4 
Exome Variant ServerUBE2D4
ExAC (Exome Aggregation Consortium)ENSG00000078967
GNOMAD BrowserENSG00000078967
Genetic variants : HAPMAP51619
Genomic Variants (DGV)UBE2D4 [DGVbeta]
DECIPHERUBE2D4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2D4 
Mutations
ICGC Data PortalUBE2D4 
TCGA Data PortalUBE2D4 
Broad Tumor PortalUBE2D4
OASIS PortalUBE2D4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2D4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2D4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2D4
DgiDB (Drug Gene Interaction Database)UBE2D4
DoCM (Curated mutations)UBE2D4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2D4 (select a term)
intoGenUBE2D4
Cancer3DUBE2D4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETUBE2D4
MedgenUBE2D4
Genetic Testing Registry UBE2D4
NextProtQ9Y2X8 [Medical]
TSGene51619
GENETestsUBE2D4
Target ValidationUBE2D4
Huge Navigator UBE2D4 [HugePedia]
snp3D : Map Gene to Disease51619
BioCentury BCIQUBE2D4
ClinGenUBE2D4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51619
Chemical/Pharm GKB GenePA134954568
Clinical trialUBE2D4
Miscellaneous
canSAR (ICR)UBE2D4 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2D4
EVEXUBE2D4
GoPubMedUBE2D4
iHOPUBE2D4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:40:29 CET 2017

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