UBE2F (ubiquitin conjugating enzyme E2 F (putative))

2007-04-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
NCE2
FUSION GENES

Other Information

Locus ID:

NCBI: 140739
MIM: 617700
HGNC: 12480
Ensembl: ENSG00000184182

Variants:

dbSNP: 140739
ClinVar: 140739
TCGA: ENSG00000184182
COSMIC: UBE2F

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184182ENST00000272930Q969M7
ENSG00000184182ENST00000409332C9IZ93
ENSG00000184182ENST00000409633Q969M7
ENSG00000184182ENST00000409953Q969M7
ENSG00000184182ENST00000414443Q969M7
ENSG00000184182ENST00000416292C9JF62
ENSG00000184182ENST00000417231F2Z363
ENSG00000184182ENST00000433241Q969M7
ENSG00000184182ENST00000433568F8WB39
ENSG00000184182ENST00000434137C9JSK8
ENSG00000184182ENST00000434655C9J9P8
ENSG00000184182ENST00000439338G5E9R6
ENSG00000184182ENST00000439780F8WD80
ENSG00000184182ENST00000440223F8WFB7
ENSG00000184182ENST00000441728Q969M7
ENSG00000184182ENST00000445676F8WCT3
ENSG00000184182ENST00000448502C9JFD2
ENSG00000184182ENST00000454786F2Z363
ENSG00000184182ENST00000455999F8WDQ9
ENSG00000184182ENST00000612130Q969M7

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232012712013Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.41
275912662017Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage.20
299328982018UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.5

Citation

Dessen P

UBE2F (ubiquitin conjugating enzyme E2 F (putative))

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47077/ube2f