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UBE2G1 (ubiquitin conjugating enzyme E2 G1)

Identity

Alias_namesUBE2G
ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7)
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)
ubiquitin-conjugating enzyme E2G 1
Alias_symbol (synonym)UBC7
Other aliasE217K
HGNC (Hugo) UBE2G1
LocusID (NCBI) 7326
Atlas_Id 47405
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 4269217 and ends at 4366674 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPD1L (3p22.3) / UBE2G1 (17p13.2)UBE2G1 (17p13.2) / AC091153.1 ()UBE2G1 (17p13.2) / RPRD1B (20q11.23)
UBE2G1 (17p13.2) / SPNS3 (17p13.2)UBE2G1 (17p13.2) / UBE2G1 (17p13.2)UBE2G1 (17p13.2) / VAC14 (16q22.1)
UBE2G1 (17p13.2) / ZZEF1 (17p13.2)UBE2G1 17p13.2 AC091153.1UBE2G1 17p13.2 / SPNS3 17p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2G1   12482
Cards
Entrez_Gene (NCBI)UBE2G1  7326  ubiquitin conjugating enzyme E2 G1
AliasesE217K; UBC7; UBE2G
GeneCards (Weizmann)UBE2G1
Ensembl hg19 (Hinxton)ENSG00000132388 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132388 [Gene_View]  chr17:4269217-4366674 [Contig_View]  UBE2G1 [Vega]
ICGC DataPortalENSG00000132388
TCGA cBioPortalUBE2G1
AceView (NCBI)UBE2G1
Genatlas (Paris)UBE2G1
WikiGenes7326
SOURCE (Princeton)UBE2G1
Genetics Home Reference (NIH)UBE2G1
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2G1  -     chr17:4269217-4366674 -  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2G1  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblUBE2G1 - 17p13.2 [CytoView hg19]  UBE2G1 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIUBE2G1 [Mapview hg19]  UBE2G1 [Mapview hg38]
OMIM601569   
Gene and transcription
Genbank (Entrez)AI493944 AK313059 BC002775 BC017006 BC026288
RefSeq transcript (Entrez)NM_003342 NM_182682
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2G1
Cluster EST : UnigeneHs.741319 [ NCBI ]
CGAP (NCI)Hs.741319
Alternative Splicing GalleryENSG00000132388
Gene ExpressionUBE2G1 [ NCBI-GEO ]   UBE2G1 [ EBI - ARRAY_EXPRESS ]   UBE2G1 [ SEEK ]   UBE2G1 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2G1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7326
GTEX Portal (Tissue expression)UBE2G1
Human Protein AtlasENSG00000132388-UBE2G1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62253   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62253  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62253
Splice isoforms : SwissVarP62253
PhosPhoSitePlusP62253
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2G1
DMDM Disease mutations7326
Blocks (Seattle)UBE2G1
PDB (SRS)2AWF   
PDB (PDBSum)2AWF   
PDB (IMB)2AWF   
PDB (RSDB)2AWF   
Structural Biology KnowledgeBase2AWF   
SCOP (Structural Classification of Proteins)2AWF   
CATH (Classification of proteins structures)2AWF   
SuperfamilyP62253
Human Protein Atlas [tissue]ENSG00000132388-UBE2G1 [tissue]
Peptide AtlasP62253
HPRD03340
IPIIPI00219783   
Protein Interaction databases
DIP (DOE-UCLA)P62253
IntAct (EBI)P62253
FunCoupENSG00000132388
BioGRIDUBE2G1
STRING (EMBL)UBE2G1
ZODIACUBE2G1
Ontologies - Pathways
QuickGOP62253
Ontology : AmiGOubiquitin-protein transferase activity  ATP binding  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  protein ubiquitination  ubiquitin protein ligase binding  cellular protein catabolic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  extracellular exosome  protein K63-linked ubiquitination  protein K48-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  ATP binding  cytoplasm  cytosol  ubiquitin-dependent protein catabolic process  protein ubiquitination  ubiquitin protein ligase binding  cellular protein catabolic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  extracellular exosome  protein K63-linked ubiquitination  protein K48-linked ubiquitination  
Pathways : BIOCARTARole of Parkin in the Ubiquitin-Proteasomal Pathway [Genes]   
Pathways : KEGGUbiquitin mediated proteolysis    Protein processing in endoplasmic reticulum    Parkinson's disease   
NDEx NetworkUBE2G1
Atlas of Cancer Signalling NetworkUBE2G1
Wikipedia pathwaysUBE2G1
Orthology - Evolution
OrthoDB7326
GeneTree (enSembl)ENSG00000132388
Phylogenetic Trees/Animal Genes : TreeFamUBE2G1
HOVERGENP62253
HOGENOMP62253
Homologs : HomoloGeneUBE2G1
Homology/Alignments : Family Browser (UCSC)UBE2G1
Gene fusions - Rearrangements
Fusion : MitelmanUBE2G1/SPNS3 [17p13.2/17p13.2]  
Fusion: TCGAUBE2G1 17p13.2 AC091153.1 OV
Fusion: TCGAUBE2G1 17p13.2 SPNS3 17p13.2 BRCA
Fusion: Tumor Portal UBE2G1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2G1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2G1
dbVarUBE2G1
ClinVarUBE2G1
1000_GenomesUBE2G1 
Exome Variant ServerUBE2G1
ExAC (Exome Aggregation Consortium)ENSG00000132388
GNOMAD BrowserENSG00000132388
Genetic variants : HAPMAP7326
Genomic Variants (DGV)UBE2G1 [DGVbeta]
DECIPHERUBE2G1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2G1 
Mutations
ICGC Data PortalUBE2G1 
TCGA Data PortalUBE2G1 
Broad Tumor PortalUBE2G1
OASIS PortalUBE2G1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2G1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2G1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2G1
DgiDB (Drug Gene Interaction Database)UBE2G1
DoCM (Curated mutations)UBE2G1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2G1 (select a term)
intoGenUBE2G1
Cancer3DUBE2G1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601569   
Orphanet
MedgenUBE2G1
Genetic Testing Registry UBE2G1
NextProtP62253 [Medical]
TSGene7326
GENETestsUBE2G1
Target ValidationUBE2G1
Huge Navigator UBE2G1 [HugePedia]
snp3D : Map Gene to Disease7326
BioCentury BCIQUBE2G1
ClinGenUBE2G1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7326
Chemical/Pharm GKB GenePA37131
Clinical trialUBE2G1
Miscellaneous
canSAR (ICR)UBE2G1 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2G1
EVEXUBE2G1
GoPubMedUBE2G1
iHOPUBE2G1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:16:24 CET 2017

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