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UBE2J1 (ubiquitin conjugating enzyme E2 J1)

Identity

Alias_namesubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
ubiquitin-conjugating enzyme E2, J1
Alias_symbol (synonym)HSPC153
CGI-76
NCUBE1
UBC6
Other aliasHSPC205
HSU93243
NCUBE-1
UBC6E
Ubc6p
HGNC (Hugo) UBE2J1
LocusID (NCBI) 51465
Atlas_Id 47111
Location 6q15  [Link to chromosome band 6q15]
Location_base_pair Starts at 89326625 and ends at 89352900 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
UBE2J1 (6q15) / RRAGD (6q15)UBE2J1 (6q15) / UBE2J1 (6q15)UBE2J1 6q15 / RRAGD 6q15

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2J1   17598
Cards
Entrez_Gene (NCBI)UBE2J1  51465  ubiquitin conjugating enzyme E2 J1
AliasesCGI-76; HSPC153; HSPC205; HSU93243; 
NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p
GeneCards (Weizmann)UBE2J1
Ensembl hg19 (Hinxton)ENSG00000198833 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198833 [Gene_View]  chr6:89326625-89352900 [Contig_View]  UBE2J1 [Vega]
ICGC DataPortalENSG00000198833
TCGA cBioPortalUBE2J1
AceView (NCBI)UBE2J1
Genatlas (Paris)UBE2J1
WikiGenes51465
SOURCE (Princeton)UBE2J1
Genetics Home Reference (NIH)UBE2J1
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2J1  -     chr6:89326625-89352900 -  6q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2J1  -     6q15   [Description]    (hg19-Feb_2009)
EnsemblUBE2J1 - 6q15 [CytoView hg19]  UBE2J1 - 6q15 [CytoView hg38]
Mapping of homologs : NCBIUBE2J1 [Mapview hg19]  UBE2J1 [Mapview hg38]
OMIM616175   
Gene and transcription
Genbank (Entrez)AB075487 AF151039 AF151834 AF161502 AJ245898
RefSeq transcript (Entrez)NM_016021
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2J1
Cluster EST : UnigeneHs.163776 [ NCBI ]
CGAP (NCI)Hs.163776
Alternative Splicing GalleryENSG00000198833
Gene ExpressionUBE2J1 [ NCBI-GEO ]   UBE2J1 [ EBI - ARRAY_EXPRESS ]   UBE2J1 [ SEEK ]   UBE2J1 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2J1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51465
GTEX Portal (Tissue expression)UBE2J1
Human Protein AtlasENSG00000198833-UBE2J1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y385   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y385  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y385
Splice isoforms : SwissVarQ9Y385
Catalytic activity : Enzyme2.3.2.23 [ Enzyme-Expasy ]   2.3.2.232.3.2.23 [ IntEnz-EBI ]   2.3.2.23 [ BRENDA ]   2.3.2.23 [ KEGG ]   
PhosPhoSitePlusQ9Y385
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2J1
DMDM Disease mutations51465
Blocks (Seattle)UBE2J1
SuperfamilyQ9Y385
Human Protein Atlas [tissue]ENSG00000198833-UBE2J1 [tissue]
Peptide AtlasQ9Y385
HPRD15599
IPIIPI00006937   IPI01011831   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y385
IntAct (EBI)Q9Y385
FunCoupENSG00000198833
BioGRIDUBE2J1
STRING (EMBL)UBE2J1
ZODIACUBE2J1
Ontologies - Pathways
QuickGOQ9Y385
Ontology : AmiGOATP binding  cytoplasm  endoplasmic reticulum membrane  spermatid development  integral component of membrane  protein ubiquitination  protein N-linked glycosylation via asparagine  ubiquitin-dependent ERAD pathway  ubiquitin protein ligase binding  regulation of tumor necrosis factor biosynthetic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  negative regulation of retrograde protein transport, ER to cytosol  
Ontology : EGO-EBIATP binding  cytoplasm  endoplasmic reticulum membrane  spermatid development  integral component of membrane  protein ubiquitination  protein N-linked glycosylation via asparagine  ubiquitin-dependent ERAD pathway  ubiquitin protein ligase binding  regulation of tumor necrosis factor biosynthetic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  negative regulation of retrograde protein transport, ER to cytosol  
Pathways : KEGGUbiquitin mediated proteolysis    Protein processing in endoplasmic reticulum    Parkinson's disease   
NDEx NetworkUBE2J1
Atlas of Cancer Signalling NetworkUBE2J1
Wikipedia pathwaysUBE2J1
Orthology - Evolution
OrthoDB51465
GeneTree (enSembl)ENSG00000198833
Phylogenetic Trees/Animal Genes : TreeFamUBE2J1
HOVERGENQ9Y385
HOGENOMQ9Y385
Homologs : HomoloGeneUBE2J1
Homology/Alignments : Family Browser (UCSC)UBE2J1
Gene fusions - Rearrangements
Fusion: TCGA_MDACCUBE2J1 6q15 RRAGD 6q15 BRCA
Tumor Fusion PortalUBE2J1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2J1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2J1
dbVarUBE2J1
ClinVarUBE2J1
1000_GenomesUBE2J1 
Exome Variant ServerUBE2J1
ExAC (Exome Aggregation Consortium)ENSG00000198833
GNOMAD BrowserENSG00000198833
Genetic variants : HAPMAP51465
Genomic Variants (DGV)UBE2J1 [DGVbeta]
DECIPHERUBE2J1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2J1 
Mutations
ICGC Data PortalUBE2J1 
TCGA Data PortalUBE2J1 
Broad Tumor PortalUBE2J1
OASIS PortalUBE2J1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2J1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2J1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2J1
DgiDB (Drug Gene Interaction Database)UBE2J1
DoCM (Curated mutations)UBE2J1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2J1 (select a term)
intoGenUBE2J1
Cancer3DUBE2J1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616175   
Orphanet
DisGeNETUBE2J1
MedgenUBE2J1
Genetic Testing Registry UBE2J1
NextProtQ9Y385 [Medical]
TSGene51465
GENETestsUBE2J1
Target ValidationUBE2J1
Huge Navigator UBE2J1 [HugePedia]
snp3D : Map Gene to Disease51465
BioCentury BCIQUBE2J1
ClinGenUBE2J1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51465
Chemical/Pharm GKB GenePA134906541
Clinical trialUBE2J1
Miscellaneous
canSAR (ICR)UBE2J1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2J1
EVEXUBE2J1
GoPubMedUBE2J1
iHOPUBE2J1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:40:31 CET 2017

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