UBE2L3 (ubiquitin-conjugating enzyme E2L 3)

Identity

Other names	E2-F1
	L-UBC
	UBCH7
	UbcM4
HGNC	UBE2L3
Location	22q11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	UBE2L3   12488
Entrez_Gene	UBE2L3  7332  ubiquitin-conjugating enzyme E2L 3
	Cards
GeneCards	UBE2L3
Ensembl	UBE2L3 [Search_View]   ENSG00000185651 [Gene_View]
Genatlas	UBE2L3
GeneLynx	UBE2L3
eGenome	UBE2L3
euGene	7332
	Genomic and cartography
GoldenPath	UBE2L3  -  22q11.2   chr22:20251957-20308323 +  22q11.21   [Description]    (hg18-March_2006)
Ensembl	UBE2L3 - 22q11.21 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2L3
	Gene and transcription
Genbank	AJ000519 [ ENTREZ ]
Genbank	AK125396 [ ENTREZ ]
Genbank	AK291083 [ ENTREZ ]
Genbank	AK311761 [ ENTREZ ]
Genbank	BC053368 [ ENTREZ ]
RefSeq	NM_003347 [ SRS ]    NM_003347 [ ENTREZ ]
RefSeq	NM_198157 [ SRS ]    NM_198157 [ ENTREZ ]
RefSeq	AC_000065 [ SRS ]    AC_000065 [ ENTREZ ]
RefSeq	AC_000154 [ SRS ]    AC_000154 [ ENTREZ ]
RefSeq	NC_000022 [ SRS ]    NC_000022 [ ENTREZ ]
RefSeq	NT_011520 [ SRS ]    NT_011520 [ ENTREZ ]
RefSeq	NW_001838745 [ SRS ]    NW_001838745 [ ENTREZ ]
RefSeq	NW_927628 [ SRS ]    NW_927628 [ ENTREZ ]
AceView	UBE2L3 AceView - NCBI
Unigene	Hs.712646 [ SRS ]    Hs.712646 [ NCBI ]     HS712646 [ spliceNest ]
Fast-db	2097 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P68036 [ SRS]    P68036 [ EXPASY ]     P68036 [ INTERPRO ]     P68036 [ UNIPROT ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR016135 UBQ-conjugat/RWD-like [ SRS ]    IPR016135 UBQ-conjugat/RWD-like [ EBI ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P68036
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P68036 UB2L3_HUMAN [ Domain structure ]   P68036 UB2L3_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P68036
PDB	1C4Z [ SRS ]    1C4Z [ PdbSum ],   1C4Z [ IMB ]   1C4Z [ RSDB ]
PDB	1FBV [ SRS ]    1FBV [ PdbSum ],   1FBV [ IMB ]   1FBV [ RSDB ]
HPRD	04762
	Protein Interaction databases
DIP	P68036
IntAct	P68036
	Polymorphism : SNP, mutations, diseases
OMIM	603721    [ map ]
GENECLINICS	603721
SNP	UBE2L3 [dbSNP-NCBI]
SNP	NM_003347 [SNP-NCI]
SNP	NM_198157 [SNP-NCI]
SNP	UBE2L3 [GeneSNPs - Utah]  UBE2L3] [HGBASE - SRS]
HAPMAP	UBE2L3 [HAPMAP]
COSMIC	UBE2L3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2L3
	General knowledge
Family Browser	UBE2L3 [UCSC Family Browser]
SOURCE	NM_003347
SOURCE	NM_198157
SMD	Hs.712646
SAGE	Hs.712646
Enzyme	6.3.2.19 [ Enzyme-Expasy ]   6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ IntEnz-EBI ]   6.3.2.19 [ BRENDA ]   6.3.2.19 [ KEGG ]   6.3.2.19 [ WIT ]
GO	ubiquitin ligase complex [Amigo]  ubiquitin ligase complex
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	ligase activity [Amigo]  ligase activity
GO	small conjugating protein ligase activity [Amigo]  small conjugating protein ligase activity
GO	enzyme binding [Amigo]  enzyme binding
GO	post-translational protein modification [Amigo]  post-translational protein modification
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
KEGG	Parkinson's disease
PubGene	UBE2L3
TreeFam	UBE2L3
CTD	7332 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	UBE2L3 Related clones (RZPD - Berlin)
	PubMed
PubMed	33 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:37:15 2008