UBE2N (ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast))

Identity

Other names	MGC131857
	MGC8489
	UBC13
	UbcH-ben
Hugo	UBE2N
Location	12q22
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	UBE2N
GDB	UBE2N
Entrez_Gene	UBE2N  7334  ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
	Cards
GeneCards	UBE2N
Ensembl	UBE2N [Search_View]   ENSG00000177889 [Gene_View]
Genatlas	UBE2N
GeneLynx	UBE2N
eGenome	UBE2N
euGene	7334
	Genomic and cartography
GoldenPath	UBE2N  -  12q22   chr12:92326219-92360157 -  12q22   [Description]    (hg18-March_2006)
Ensembl	UBE2N - 12q22 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	UBE2N
	Gene and transcription
Genbank	AK098233 [ ENTREZ ]
Genbank	AL110140 [ ENTREZ ]
Genbank	BC000396 [ ENTREZ ]
Genbank	BC003365 [ ENTREZ ]
Genbank	BC108704 [ ENTREZ ]
RefSeq	NM_003348 [ SRS ]    NM_003348 [ ENTREZ ]
RefSeq	AC_000055 [ SRS ]    AC_000055 [ ENTREZ ]
RefSeq	NC_000012 [ SRS ]    NC_000012 [ ENTREZ ]
RefSeq	NT_019546 [ SRS ]    NT_019546 [ ENTREZ ]
RefSeq	NW_925395 [ SRS ]    NW_925395 [ ENTREZ ]
AceView	UBE2N AceView - NCBI
Unigene	Hs.524630 [ SRS ]    Hs.524630 [ NCBI ]     HS524630 [ spliceNest ]
Fast-db	11525 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P61088 [ SRS]    P61088 [ EXPASY ]     P61088 [ INTERPRO ]
Prosite	PS00183 UBIQUITIN_CONJUGAT_1 [ SRS ]    PS00183 UBIQUITIN_CONJUGAT_1 [ Expasy ]
Prosite	PS50127 UBIQUITIN_CONJUGAT_2 [ SRS ]    PS50127 UBIQUITIN_CONJUGAT_2 [ Expasy ]
Interpro	IPR000608 UBQ-conjugat_E2 [ SRS ]    IPR000608 UBQ-conjugat_E2 [ EBI ]
CluSTr	P61088
Pfam	PF00179 UQ_con [ SRS ]    PF00179 UQ_con [ Sanger ]    pfam00179 [ NCBI-CDD ]
Smart	SM00212 UBCc [EMBL]
Prodom	PD000461 UBQ_conjugat[INRA-Toulouse]
Prodom	P61088 UBE2N_HUMAN [ Domain structure ]   P61088 UBE2N_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P61088
PDB	1J7D [ SRS ]    1J7D [ PdbSum ],   1J7D [ IMB ]   1J7D [ RSDB ]
PDB	2C2V [ SRS ]    2C2V [ PdbSum ],   2C2V [ IMB ]   2C2V [ RSDB ]
HPRD	04725
	Protein Interaction databases
DIP	P61088
IntAct	P61088
	Polymorphism : SNP, mutations, diseases
OMIM	603679    [ map ]
GENECLINICS	603679
SNP	UBE2N [dbSNP-NCBI]
SNP	NM_003348 [SNP-NCI]
SNP	UBE2N [GeneSNPs - Utah]  UBE2N] [HGBASE - SRS]
HAPMAP	UBE2N [HAPMAP]
COSMIC	UBE2N [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	UBE2N
	General knowledge
Family Browser	UBE2N [UCSC Family Browser]
SOURCE	NM_003348
SMD	Hs.524630
SAGE	Hs.524630
Enzyme	6.3.2.19 [ Enzyme-SRS ]   6.3.2.19 [ Brenda-SRS ]   6.3.2.19 [ KEGG ]   6.3.2.19 [ WIT ]
GO	double-strand break repair via homologous recombination [Amigo]  double-strand break repair via homologous recombination
GO	DNA double-strand break processing [Amigo]  DNA double-strand break processing
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	postreplication repair [Amigo]  postreplication repair
GO	proteolysis [Amigo]  proteolysis
GO	ligase activity [Amigo]  ligase activity
GO	positive regulation of histone modification [Amigo]  positive regulation of histone modification
GO	UBC13-MMS2 complex [Amigo]  UBC13-MMS2 complex
GO	regulation of histone ubiquitination [Amigo]  regulation of histone ubiquitination
GO	positive regulation of I-kappaB kinase/NF-kappaB cascade [Amigo]  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO	ubiquitin binding [Amigo]  ubiquitin binding
GO	positive regulation of DNA repair [Amigo]  positive regulation of DNA repair
GO	T cell receptor signaling pathway [Amigo]  T cell receptor signaling pathway
GO	activation of NF-kappaB transcription factor [Amigo]  activation of NF-kappaB transcription factor
GO	regulation of protein metabolic process [Amigo]  regulation of protein metabolic process
GO	positive regulation of ubiquitin-protein ligase activity [Amigo]  positive regulation of ubiquitin-protein ligase activity
PubGene	UBE2N
TreeFam	UBE2N
CTD	7334 [Comparative Genomics Database]
	Other databases
	Probes
Probe	UBE2N Related clones (RZPD - Berlin)
	PubMed
PubMed	29 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:34:10 2008