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UBE2Q1 (ubiquitin conjugating enzyme E2 Q1)

Identity

Alias_namesUBE2Q
ubiquitin-conjugating enzyme E2Q (putative)
ubiquitin-conjugating enzyme E2Q family member 1
Alias_symbol (synonym)PRO3094
NICE-5
Other aliasGTAP
NICE5
HGNC (Hugo) UBE2Q1
LocusID (NCBI) 55585
Atlas_Id 47015
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 154548575 and ends at 154558644 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
UBE2Q1 (1q21.3) / ATP2A2 (12q24.11)UBE2Q1 (1q21.3) / HPS1 (10q24.2)UBE2Q1 (1q21.3) / MAEL (1q24.1)
UBE2Q1 (1q21.3) / UBE2Q1 (1q21.3)UBE2Q1 (1q21.3) / VPS72 (1q21.3)UBE2Q1 1q21.3 / HPS1 10q24.2
UBE2Q1 1q21.3 / MAEL 1q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2Q1   15698
Cards
Entrez_Gene (NCBI)UBE2Q1  55585  ubiquitin conjugating enzyme E2 Q1
AliasesGTAP; NICE-5; NICE5; PRO3094; 
UBE2Q
GeneCards (Weizmann)UBE2Q1
Ensembl hg19 (Hinxton)ENSG00000160714 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160714 [Gene_View]  chr1:154548575-154558644 [Contig_View]  UBE2Q1 [Vega]
ICGC DataPortalENSG00000160714
TCGA cBioPortalUBE2Q1
AceView (NCBI)UBE2Q1
Genatlas (Paris)UBE2Q1
WikiGenes55585
SOURCE (Princeton)UBE2Q1
Genetics Home Reference (NIH)UBE2Q1
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2Q1  -     chr1:154548575-154558644 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2Q1  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblUBE2Q1 - 1q21.3 [CytoView hg19]  UBE2Q1 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIUBE2Q1 [Mapview hg19]  UBE2Q1 [Mapview hg38]
OMIM617429   
Gene and transcription
Genbank (Entrez)AF116721 AJ243666 AK056388 AK293986 AY112698
RefSeq transcript (Entrez)NM_017582
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2Q1
Cluster EST : UnigeneHs.607928 [ NCBI ]
CGAP (NCI)Hs.607928
Alternative Splicing GalleryENSG00000160714
Gene ExpressionUBE2Q1 [ NCBI-GEO ]   UBE2Q1 [ EBI - ARRAY_EXPRESS ]   UBE2Q1 [ SEEK ]   UBE2Q1 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2Q1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55585
GTEX Portal (Tissue expression)UBE2Q1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7E8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7E8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7E8
Splice isoforms : SwissVarQ7Z7E8
Catalytic activity : Enzyme2.3.2.23 [ Enzyme-Expasy ]   2.3.2.232.3.2.23 [ IntEnz-EBI ]   2.3.2.23 [ BRENDA ]   2.3.2.23 [ KEGG ]   
PhosPhoSitePlusQ7Z7E8
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2Q1
DMDM Disease mutations55585
Blocks (Seattle)UBE2Q1
PDB (SRS)2QGX   
PDB (PDBSum)2QGX   
PDB (IMB)2QGX   
PDB (RSDB)2QGX   
Structural Biology KnowledgeBase2QGX   
SCOP (Structural Classification of Proteins)2QGX   
CATH (Classification of proteins structures)2QGX   
SuperfamilyQ7Z7E8
Human Protein AtlasENSG00000160714
Peptide AtlasQ7Z7E8
HPRD15601
IPIIPI00333410   IPI00719397   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7E8
IntAct (EBI)Q7Z7E8
FunCoupENSG00000160714
BioGRIDUBE2Q1
STRING (EMBL)UBE2Q1
ZODIACUBE2Q1
Ontologies - Pathways
QuickGOQ7Z7E8
Ontology : AmiGOsuckling behavior  protein binding  ATP binding  nucleus  cytosol  embryo implantation  mating behavior  fertilization  protein ubiquitination  filopodium  reproductive system development  ubiquitin conjugating enzyme activity  prolactin secretion  
Ontology : EGO-EBIsuckling behavior  protein binding  ATP binding  nucleus  cytosol  embryo implantation  mating behavior  fertilization  protein ubiquitination  filopodium  reproductive system development  ubiquitin conjugating enzyme activity  prolactin secretion  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2Q1
Atlas of Cancer Signalling NetworkUBE2Q1
Wikipedia pathwaysUBE2Q1
Orthology - Evolution
OrthoDB55585
GeneTree (enSembl)ENSG00000160714
Phylogenetic Trees/Animal Genes : TreeFamUBE2Q1
HOVERGENQ7Z7E8
HOGENOMQ7Z7E8
Homologs : HomoloGeneUBE2Q1
Homology/Alignments : Family Browser (UCSC)UBE2Q1
Gene fusions - Rearrangements
Fusion : MitelmanUBE2Q1/HPS1 [1q21.3/10q24.2]  
Fusion : MitelmanUBE2Q1/MAEL [1q21.3/1q24.1]  [t(1;1)(q21;q24)]  
Fusion: TCGAUBE2Q1 1q21.3 HPS1 10q24.2 BRCA
Fusion: TCGAUBE2Q1 1q21.3 MAEL 1q24.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2Q1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2Q1
dbVarUBE2Q1
ClinVarUBE2Q1
1000_GenomesUBE2Q1 
Exome Variant ServerUBE2Q1
ExAC (Exome Aggregation Consortium)UBE2Q1 (select the gene name)
Genetic variants : HAPMAP55585
Genomic Variants (DGV)UBE2Q1 [DGVbeta]
DECIPHERUBE2Q1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2Q1 
Mutations
ICGC Data PortalUBE2Q1 
TCGA Data PortalUBE2Q1 
Broad Tumor PortalUBE2Q1
OASIS PortalUBE2Q1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2Q1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2Q1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2Q1
DgiDB (Drug Gene Interaction Database)UBE2Q1
DoCM (Curated mutations)UBE2Q1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2Q1 (select a term)
intoGenUBE2Q1
Cancer3DUBE2Q1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617429   
Orphanet
MedgenUBE2Q1
Genetic Testing Registry UBE2Q1
NextProtQ7Z7E8 [Medical]
TSGene55585
GENETestsUBE2Q1
Target ValidationUBE2Q1
Huge Navigator UBE2Q1 [HugePedia]
snp3D : Map Gene to Disease55585
BioCentury BCIQUBE2Q1
ClinGenUBE2Q1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55585
Chemical/Pharm GKB GenePA38029
Clinical trialUBE2Q1
Miscellaneous
canSAR (ICR)UBE2Q1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2Q1
EVEXUBE2Q1
GoPubMedUBE2Q1
iHOPUBE2Q1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:01:40 CEST 2017

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