UBE2Q2 (ubiquitin conjugating enzyme E2 Q2)

2007-02-01  

Identity

HGNC
LOCATION
15q24.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 92912
MIM: 612501
HGNC: 19248
Ensembl: ENSG00000140367

Variants:

dbSNP: 92912
ClinVar: 92912
TCGA: ENSG00000140367
COSMIC: UBE2Q2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140367ENST00000267938Q8WVN8
ENSG00000140367ENST00000426727E9PHD0
ENSG00000140367ENST00000561723H3BV95
ENSG00000140367ENST00000561851Q8WVN8
ENSG00000140367ENST00000567921H3BN94
ENSG00000140367ENST00000569423Q8WVN8

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168
Protein ubiquitinationREACTOMER-HSA-8852135
Synthesis of active ubiquitin: roles of E1 and E2 enzymesREACTOMER-HSA-8866652

References

Pubmed IDYearTitleCitations
203831462010New loci associated with kidney function and chronic kidney disease.337
226422442012Expression of UBE2Q2, a putative member of the ubiquitin-conjugating enzyme family in pediatric acute lymphoblastic leukemia.10
201938422010Overexpression of the novel human gene, UBE2Q2, in breast cancer.9
174712412007Inactivation of the ubiquitin conjugating enzyme UBE2Q2 causes a prophase arrest and enhanced apoptosis in response to microtubule inhibiting agents.8
197238762009Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer.6
163007362006Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours.5
267450682015Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.4

Citation

Dessen P

UBE2Q2 (ubiquitin conjugating enzyme E2 Q2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45984/ube2q2