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UBE2Q2 (ubiquitin conjugating enzyme E2 Q2)

Identity

Alias_namesubiquitin-conjugating enzyme E2Q (putative) 2
ubiquitin-conjugating enzyme E2Q family member 2
Alias_symbol (synonym)DKFZp762C143
Other alias-
HGNC (Hugo) UBE2Q2
LocusID (NCBI) 92912
Atlas_Id 45984
Location 15q24.2  [Link to chromosome band 15q24]
Location_base_pair Starts at 75844044 and ends at 75901047 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXO22 (15q24.2) / UBE2Q2 (15q24.2)UBE2Q2 (15q24.2) / GOLGA8A (15q14)UBE2Q2 (15q24.2) / GOLGA8B (15q14)
UBE2Q2 (15q24.2) / NFRKB (11q24.3)UBE2Q2 (15q24.2) / NRG4 (15q24.2)UBE2Q2 (15q24.2) / ODF3L1 (15q24.2)
UBE2Q2 15q24.2 / NRG4 15q24.2UBE2Q2 15q24.2 / ODF3L1 15q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2Q2   19248
Cards
Entrez_Gene (NCBI)UBE2Q2  92912  ubiquitin conjugating enzyme E2 Q2
Aliases
GeneCards (Weizmann)UBE2Q2
Ensembl hg19 (Hinxton)ENSG00000140367 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140367 [Gene_View]  chr15:75844044-75901047 [Contig_View]  UBE2Q2 [Vega]
ICGC DataPortalENSG00000140367
TCGA cBioPortalUBE2Q2
AceView (NCBI)UBE2Q2
Genatlas (Paris)UBE2Q2
WikiGenes92912
SOURCE (Princeton)UBE2Q2
Genetics Home Reference (NIH)UBE2Q2
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2Q2  -     chr15:75844044-75901047 +  15q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2Q2  -     15q24.2   [Description]    (hg19-Feb_2009)
EnsemblUBE2Q2 - 15q24.2 [CytoView hg19]  UBE2Q2 - 15q24.2 [CytoView hg38]
Mapping of homologs : NCBIUBE2Q2 [Mapview hg19]  UBE2Q2 [Mapview hg38]
OMIM612501   
Gene and transcription
Genbank (Entrez)AA476260 AK000617 AK294199 AK296234 AL117641
RefSeq transcript (Entrez)NM_001145335 NM_001284382 NM_173469
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2Q2
Cluster EST : UnigeneHs.23033 [ NCBI ]
CGAP (NCI)Hs.23033
Alternative Splicing GalleryENSG00000140367
Gene ExpressionUBE2Q2 [ NCBI-GEO ]   UBE2Q2 [ EBI - ARRAY_EXPRESS ]   UBE2Q2 [ SEEK ]   UBE2Q2 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2Q2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92912
GTEX Portal (Tissue expression)UBE2Q2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVN8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVN8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVN8
Splice isoforms : SwissVarQ8WVN8
PhosPhoSitePlusQ8WVN8
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2Q2
DMDM Disease mutations92912
Blocks (Seattle)UBE2Q2
PDB (SRS)1ZUO   
PDB (PDBSum)1ZUO   
PDB (IMB)1ZUO   
PDB (RSDB)1ZUO   
Structural Biology KnowledgeBase1ZUO   
SCOP (Structural Classification of Proteins)1ZUO   
CATH (Classification of proteins structures)1ZUO   
SuperfamilyQ8WVN8
Human Protein AtlasENSG00000140367
Peptide AtlasQ8WVN8
HPRD14294
IPIIPI00103165   IPI00386815   IPI00953407   IPI00922714   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVN8
IntAct (EBI)Q8WVN8
FunCoupENSG00000140367
BioGRIDUBE2Q2
STRING (EMBL)UBE2Q2
ZODIACUBE2Q2
Ontologies - Pathways
QuickGOQ8WVN8
Ontology : AmiGOubiquitin-protein transferase activity  ATP binding  cytosol  protein ubiquitination  ubiquitin conjugating enzyme activity  protein K48-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  ATP binding  cytosol  protein ubiquitination  ubiquitin conjugating enzyme activity  protein K48-linked ubiquitination  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2Q2
Atlas of Cancer Signalling NetworkUBE2Q2
Wikipedia pathwaysUBE2Q2
Orthology - Evolution
OrthoDB92912
GeneTree (enSembl)ENSG00000140367
Phylogenetic Trees/Animal Genes : TreeFamUBE2Q2
HOVERGENQ8WVN8
HOGENOMQ8WVN8
Homologs : HomoloGeneUBE2Q2
Homology/Alignments : Family Browser (UCSC)UBE2Q2
Gene fusions - Rearrangements
Fusion : MitelmanUBE2Q2/NRG4 [15q24.2/15q24.2]  
Fusion : MitelmanUBE2Q2/ODF3L1 [15q24.2/15q24.2]  [t(15;15)(q24;q24)]  
Fusion: TCGAUBE2Q2 15q24.2 NRG4 15q24.2 BRCA
Fusion: TCGAUBE2Q2 15q24.2 ODF3L1 15q24.2 BRCA
Fusion Cancer (Beijing)UBE2Q2 [15q24.2]  -  GOLGA8A [15q14]  [FUSC001448]  [FUSC001448]  [FUSC001448]
Fusion Cancer (Beijing)UBE2Q2 [15q24.2]  -  GOLGA8B [15q14]  [FUSC001449]  [FUSC001449]  [FUSC001449]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2Q2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2Q2
dbVarUBE2Q2
ClinVarUBE2Q2
1000_GenomesUBE2Q2 
Exome Variant ServerUBE2Q2
ExAC (Exome Aggregation Consortium)UBE2Q2 (select the gene name)
Genetic variants : HAPMAP92912
Genomic Variants (DGV)UBE2Q2 [DGVbeta]
DECIPHERUBE2Q2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2Q2 
Mutations
ICGC Data PortalUBE2Q2 
TCGA Data PortalUBE2Q2 
Broad Tumor PortalUBE2Q2
OASIS PortalUBE2Q2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2Q2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2Q2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2Q2
DgiDB (Drug Gene Interaction Database)UBE2Q2
DoCM (Curated mutations)UBE2Q2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2Q2 (select a term)
intoGenUBE2Q2
Cancer3DUBE2Q2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612501   
Orphanet
MedgenUBE2Q2
Genetic Testing Registry UBE2Q2
NextProtQ8WVN8 [Medical]
TSGene92912
GENETestsUBE2Q2
Target ValidationUBE2Q2
Huge Navigator UBE2Q2 [HugePedia]
snp3D : Map Gene to Disease92912
BioCentury BCIQUBE2Q2
ClinGenUBE2Q2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92912
Chemical/Pharm GKB GenePA142670652
Clinical trialUBE2Q2
Miscellaneous
canSAR (ICR)UBE2Q2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2Q2
EVEXUBE2Q2
GoPubMedUBE2Q2
iHOPUBE2Q2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:18:12 CEST 2017

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