UBE2R2 (ubiquitin conjugating enzyme E2 R2)

2007-04-01  

Identity

HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
CDC34B,E2-CDC34B,UBC3B
FUSION GENES

Other Information

Locus ID:

NCBI: 54926
MIM: 612506
HGNC: 19907
Ensembl: ENSG00000107341

Variants:

dbSNP: 54926
ClinVar: 54926
TCGA: ENSG00000107341
COSMIC: UBE2R2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107341ENST00000263228Q712K3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Herpes simplex infectionKEGGko05168
Herpes simplex infectionKEGGhsa05168
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168
Protein ubiquitinationREACTOMER-HSA-8852135
Synthesis of active ubiquitin: roles of E1 and E2 enzymesREACTOMER-HSA-8866652

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
120376802002CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation.15
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
318685892019Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways.3
270448682016Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme.2

Citation

Dessen P

UBE2R2 (ubiquitin conjugating enzyme E2 R2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46910/ube2r2