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UBE2R2 (ubiquitin conjugating enzyme E2 R2)

Identity

Alias_namesubiquitin-conjugating enzyme E2R 2
Alias_symbol (synonym)UBC3B
CDC34B
FLJ20419
MGC10481
Other aliasE2-CDC34B
HGNC (Hugo) UBE2R2
LocusID (NCBI) 54926
Atlas_Id 46910
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 33817184 and ends at 33920403 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLTA (9p13.3) / UBE2R2 (9p13.3)EPB41L4B (9q31.3) / UBE2R2 (9p13.3)LPP (3q28) / UBE2R2 (9p13.3)
MYO18B (22q12.1) / UBE2R2 (9p13.3)NAP1L4 (11p15.4) / UBE2R2 (9p13.3)TTLL1 (22q13.2) / UBE2R2 (9p13.3)
UBE2R2 (9p13.3) / KRT1 (12q13.13)UBE2R2 (9p13.3) / PRSS3 (9p13.3)UBE2R2 (9p13.3) / ST6GAL1 (3q27.3)
UBE2R2 (9p13.3) / UBE2R2 (9p13.3)CLTA 9p13.3 / UBE2R2 9p13.3MYO18B 22q12.1 / UBE2R2 9p13.3
UBE2R2 9p13.3 / PRSS3 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2R2   19907
Cards
Entrez_Gene (NCBI)UBE2R2  54926  ubiquitin conjugating enzyme E2 R2
AliasesCDC34B; E2-CDC34B; UBC3B
GeneCards (Weizmann)UBE2R2
Ensembl hg19 (Hinxton)ENSG00000107341 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107341 [Gene_View]  chr9:33817184-33920403 [Contig_View]  UBE2R2 [Vega]
ICGC DataPortalENSG00000107341
TCGA cBioPortalUBE2R2
AceView (NCBI)UBE2R2
Genatlas (Paris)UBE2R2
WikiGenes54926
SOURCE (Princeton)UBE2R2
Genetics Home Reference (NIH)UBE2R2
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2R2  -     chr9:33817184-33920403 +  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2R2  -     9p13.3   [Description]    (hg19-Feb_2009)
EnsemblUBE2R2 - 9p13.3 [CytoView hg19]  UBE2R2 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBIUBE2R2 [Mapview hg19]  UBE2R2 [Mapview hg38]
OMIM612506   
Gene and transcription
Genbank (Entrez)AA397839 AJ240087 AK000426 AK225880 AL133827
RefSeq transcript (Entrez)NM_017811
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2R2
Cluster EST : UnigeneHs.643648 [ NCBI ]
CGAP (NCI)Hs.643648
Alternative Splicing GalleryENSG00000107341
Gene ExpressionUBE2R2 [ NCBI-GEO ]   UBE2R2 [ EBI - ARRAY_EXPRESS ]   UBE2R2 [ SEEK ]   UBE2R2 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2R2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54926
GTEX Portal (Tissue expression)UBE2R2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ712K3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ712K3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ712K3
Splice isoforms : SwissVarQ712K3
PhosPhoSitePlusQ712K3
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2R2
DMDM Disease mutations54926
Blocks (Seattle)UBE2R2
SuperfamilyQ712K3
Human Protein AtlasENSG00000107341
Peptide AtlasQ712K3
HPRD15602
IPIIPI00418603   
Protein Interaction databases
DIP (DOE-UCLA)Q712K3
IntAct (EBI)Q712K3
FunCoupENSG00000107341
BioGRIDUBE2R2
STRING (EMBL)UBE2R2
ZODIACUBE2R2
Ontologies - Pathways
QuickGOQ712K3
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  ATP binding  cytoplasm  cytosol  protein monoubiquitination  protein ubiquitination  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  protein K48-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  ATP binding  cytoplasm  cytosol  protein monoubiquitination  protein ubiquitination  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  ubiquitin conjugating enzyme activity  protein K48-linked ubiquitination  
Pathways : KEGGUbiquitin mediated proteolysis    Herpes simplex infection   
NDEx NetworkUBE2R2
Atlas of Cancer Signalling NetworkUBE2R2
Wikipedia pathwaysUBE2R2
Orthology - Evolution
OrthoDB54926
GeneTree (enSembl)ENSG00000107341
Phylogenetic Trees/Animal Genes : TreeFamUBE2R2
HOVERGENQ712K3
HOGENOMQ712K3
Homologs : HomoloGeneUBE2R2
Homology/Alignments : Family Browser (UCSC)UBE2R2
Gene fusions - Rearrangements
Fusion : MitelmanCLTA/UBE2R2 [9p13.3/9p13.3]  [t(9;9)(p13;p13)]  
Fusion : MitelmanMYO18B/UBE2R2 [22q12.1/9p13.3]  [t(9;22)(p13;q12)]  
Fusion : MitelmanUBE2R2/PRSS3 [9p13.3/9p13.3]  [t(9;9)(p13;p13)]  
Fusion: TCGACLTA 9p13.3 UBE2R2 9p13.3 GBM
Fusion: TCGAMYO18B 22q12.1 UBE2R2 9p13.3 GBM
Fusion: TCGAUBE2R2 9p13.3 PRSS3 9p13.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2R2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2R2
dbVarUBE2R2
ClinVarUBE2R2
1000_GenomesUBE2R2 
Exome Variant ServerUBE2R2
ExAC (Exome Aggregation Consortium)UBE2R2 (select the gene name)
Genetic variants : HAPMAP54926
Genomic Variants (DGV)UBE2R2 [DGVbeta]
DECIPHERUBE2R2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2R2 
Mutations
ICGC Data PortalUBE2R2 
TCGA Data PortalUBE2R2 
Broad Tumor PortalUBE2R2
OASIS PortalUBE2R2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2R2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2R2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2R2
DgiDB (Drug Gene Interaction Database)UBE2R2
DoCM (Curated mutations)UBE2R2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2R2 (select a term)
intoGenUBE2R2
Cancer3DUBE2R2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612506   
Orphanet
MedgenUBE2R2
Genetic Testing Registry UBE2R2
NextProtQ712K3 [Medical]
TSGene54926
GENETestsUBE2R2
Target ValidationUBE2R2
Huge Navigator UBE2R2 [HugePedia]
snp3D : Map Gene to Disease54926
BioCentury BCIQUBE2R2
ClinGenUBE2R2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54926
Chemical/Pharm GKB GenePA134946881
Clinical trialUBE2R2
Miscellaneous
canSAR (ICR)UBE2R2 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2R2
EVEXUBE2R2
GoPubMedUBE2R2
iHOPUBE2R2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:09 CEST 2017

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