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UBE2U (ubiquitin conjugating enzyme E2 U)

Identity

Alias_namesubiquitin-conjugating enzyme E2U (putative)
Alias_symbol (synonym)MGC35130
Other alias-
HGNC (Hugo) UBE2U
LocusID (NCBI) 148581
Atlas_Id 54994
Location 1p31.3  [Link to chromosome band 1p31]
Location_base_pair Starts at 64203618 and ends at 64246274 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2U   28559
Cards
Entrez_Gene (NCBI)UBE2U  148581  ubiquitin conjugating enzyme E2 U
Aliases
GeneCards (Weizmann)UBE2U
Ensembl hg19 (Hinxton)ENSG00000177414 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177414 [Gene_View]  ENSG00000177414 [Sequence]  chr1:64203618-64246274 [Contig_View]  UBE2U [Vega]
ICGC DataPortalENSG00000177414
TCGA cBioPortalUBE2U
AceView (NCBI)UBE2U
Genatlas (Paris)UBE2U
WikiGenes148581
SOURCE (Princeton)UBE2U
Genetics Home Reference (NIH)UBE2U
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2U  -     chr1:64203618-64246274 +  1p31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2U  -     1p31.3   [Description]    (hg19-Feb_2009)
EnsemblUBE2U - 1p31.3 [CytoView hg19]  UBE2U - 1p31.3 [CytoView hg38]
Mapping of homologs : NCBIUBE2U [Mapview hg19]  UBE2U [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC029895 BG773201 BX112562 HM005529
RefSeq transcript (Entrez)NM_001366232 NM_001366233 NM_001366234 NM_001366235 NM_152489
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2U
Cluster EST : UnigeneHs.656862 [ NCBI ]
CGAP (NCI)Hs.656862
Alternative Splicing GalleryENSG00000177414
Gene ExpressionUBE2U [ NCBI-GEO ]   UBE2U [ EBI - ARRAY_EXPRESS ]   UBE2U [ SEEK ]   UBE2U [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2U [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)148581
GTEX Portal (Tissue expression)UBE2U
Human Protein AtlasENSG00000177414-UBE2U [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VVX9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VVX9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VVX9
Splice isoforms : SwissVarQ5VVX9
Catalytic activity : Enzyme2.3.2.23 [ Enzyme-Expasy ]   2.3.2.232.3.2.23 [ IntEnz-EBI ]   2.3.2.23 [ BRENDA ]   2.3.2.23 [ KEGG ]   
PhosPhoSitePlusQ5VVX9
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_1 (PS00183)    UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_AS    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2U
DMDM Disease mutations148581
Blocks (Seattle)UBE2U
PDB (SRS)1YRV   
PDB (PDBSum)1YRV   
PDB (IMB)1YRV   
PDB (RSDB)1YRV   
Structural Biology KnowledgeBase1YRV   
SCOP (Structural Classification of Proteins)1YRV   
CATH (Classification of proteins structures)1YRV   
SuperfamilyQ5VVX9
Human Protein Atlas [tissue]ENSG00000177414-UBE2U [tissue]
Peptide AtlasQ5VVX9
HPRD14599
IPIIPI00166140   IPI00645714   
Protein Interaction databases
DIP (DOE-UCLA)Q5VVX9
IntAct (EBI)Q5VVX9
FunCoupENSG00000177414
BioGRIDUBE2U
STRING (EMBL)UBE2U
ZODIACUBE2U
Ontologies - Pathways
QuickGOQ5VVX9
Ontology : AmiGOprotein polyubiquitination  nuclear chromatin  protein binding  ATP binding  DNA repair  HULC complex  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin conjugating enzyme activity  
Ontology : EGO-EBIprotein polyubiquitination  nuclear chromatin  protein binding  ATP binding  DNA repair  HULC complex  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin conjugating enzyme activity  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2U
Atlas of Cancer Signalling NetworkUBE2U
Wikipedia pathwaysUBE2U
Orthology - Evolution
OrthoDB148581
GeneTree (enSembl)ENSG00000177414
Phylogenetic Trees/Animal Genes : TreeFamUBE2U
HOVERGENQ5VVX9
HOGENOMQ5VVX9
Homologs : HomoloGeneUBE2U
Homology/Alignments : Family Browser (UCSC)UBE2U
Gene fusions - Rearrangements
Fusion : QuiverUBE2U
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2U [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2U
dbVarUBE2U
ClinVarUBE2U
1000_GenomesUBE2U 
Exome Variant ServerUBE2U
ExAC (Exome Aggregation Consortium)ENSG00000177414
GNOMAD BrowserENSG00000177414
Varsome BrowserUBE2U
Genetic variants : HAPMAP148581
Genomic Variants (DGV)UBE2U [DGVbeta]
DECIPHERUBE2U [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2U 
Mutations
ICGC Data PortalUBE2U 
TCGA Data PortalUBE2U 
Broad Tumor PortalUBE2U
OASIS PortalUBE2U [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2U  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2U
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2U
DgiDB (Drug Gene Interaction Database)UBE2U
DoCM (Curated mutations)UBE2U (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2U (select a term)
intoGenUBE2U
Cancer3DUBE2U(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETUBE2U
MedgenUBE2U
Genetic Testing Registry UBE2U
NextProtQ5VVX9 [Medical]
TSGene148581
GENETestsUBE2U
Target ValidationUBE2U
Huge Navigator UBE2U [HugePedia]
snp3D : Map Gene to Disease148581
BioCentury BCIQUBE2U
ClinGenUBE2U
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD148581
Chemical/Pharm GKB GenePA142670656
Clinical trialUBE2U
Miscellaneous
canSAR (ICR)UBE2U (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2U
EVEXUBE2U
GoPubMedUBE2U
iHOPUBE2U
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:48:09 CET 2018

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