Atlas of Genetics and Cytogenetics in Oncology and Haematology


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UBE2V1 (ubiquitin conjugating enzyme E2 V1)

Identity

Alias_namesUBE2V
ubiquitin-conjugating enzyme E2 variant 1
Alias_symbol (synonym)UEV-1
CROC-1
UEV1A
CROC1
Other aliasCIR1
UEV1
HGNC (Hugo) UBE2V1
LocusID (NCBI) 7335
Atlas_Id 42754
Location 20q13.13  [Link to chromosome band 20q13]
Location_base_pair Starts at 48697661 and ends at 48729735 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATF5 (19q13.33) / UBE2V1 (20q13.13)EXPH5 (11q22.3) / UBE2V1 (20q13.13)FKBP11 (12q13.12) / UBE2V1 (20q13.13)
LARGE (22q12.3) / UBE2V1 (20q13.13)TMEM189 (20q13.13) / UBE2V1 (20q13.13)UBE2V1 (20q13.13) / ARFGEF1 (8q13.2)
UBE2V1 (20q13.13) / CLU (8p21.1)UBE2V1 (20q13.13) / DHTKD1 (10p14)UBE2V1 (20q13.13) / PARP6 (15q23)
UBE2V1 (20q13.13) / PRKAG1 (12q13.12)UBE2V1 (20q13.13) / RNF114 (20q13.13)UBE2V1 (20q13.13) / SRP9 (1q42.12)
UBE2V1 (20q13.13) / SULF2 (20q13.12)UBE2V1 (20q13.13) / UBE2V1 (20q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2V1   12494
Cards
Entrez_Gene (NCBI)UBE2V1  7335  ubiquitin conjugating enzyme E2 V1
AliasesCIR1; CROC-1; CROC1; UBE2V; 
UEV-1; UEV1; UEV1A
GeneCards (Weizmann)UBE2V1
Ensembl hg19 (Hinxton)ENSG00000244687 [Gene_View]  chr20:48697661-48729735 [Contig_View]  UBE2V1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000244687 [Gene_View]  chr20:48697661-48729735 [Contig_View]  UBE2V1 [Vega]
ICGC DataPortalENSG00000244687
TCGA cBioPortalUBE2V1
AceView (NCBI)UBE2V1
Genatlas (Paris)UBE2V1
WikiGenes7335
SOURCE (Princeton)UBE2V1
Genetics Home Reference (NIH)UBE2V1
Genomic and cartography
GoldenPath hg19 (UCSC)UBE2V1  -     chr20:48697661-48729735 -  20q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)UBE2V1  -     20q13.13   [Description]    (hg38-Dec_2013)
EnsemblUBE2V1 - 20q13.13 [CytoView hg19]  UBE2V1 - 20q13.13 [CytoView hg38]
Mapping of homologs : NCBIUBE2V1 [Mapview hg19]  UBE2V1 [Mapview hg38]
OMIM602995   
Gene and transcription
Genbank (Entrez)AF049671 AI688615 AK314754 AL110132 AY008273
RefSeq transcript (Entrez)NM_001032288 NM_001257393 NM_001257394 NM_001257395 NM_001257396 NM_001257397 NM_001257398 NM_001257399 NM_001282575 NM_001282576 NM_001282577 NM_001282578 NM_001282579 NM_001282580 NM_021988 NM_022442 NM_199144
RefSeq genomic (Entrez)NC_000020 NC_018931 NG_029526 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)UBE2V1
Cluster EST : UnigeneHs.744839 [ NCBI ]
CGAP (NCI)Hs.744839
Alternative Splicing GalleryENSG00000244687
Gene ExpressionUBE2V1 [ NCBI-GEO ]   UBE2V1 [ EBI - ARRAY_EXPRESS ]   UBE2V1 [ SEEK ]   UBE2V1 [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2V1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7335
GTEX Portal (Tissue expression)UBE2V1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13404   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13404  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13404
Splice isoforms : SwissVarQ13404
PhosPhoSitePlusQ13404
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2V1
DMDM Disease mutations7335
Blocks (Seattle)UBE2V1
PDB (SRS)2A4D    2C2V    2HLW   
PDB (PDBSum)2A4D    2C2V    2HLW   
PDB (IMB)2A4D    2C2V    2HLW   
PDB (RSDB)2A4D    2C2V    2HLW   
Structural Biology KnowledgeBase2A4D    2C2V    2HLW   
SCOP (Structural Classification of Proteins)2A4D    2C2V    2HLW   
CATH (Classification of proteins structures)2A4D    2C2V    2HLW   
SuperfamilyQ13404
Human Protein AtlasENSG00000244687
Peptide AtlasQ13404
Protein Interaction databases
DIP (DOE-UCLA)Q13404
IntAct (EBI)Q13404
FunCoupENSG00000244687
BioGRIDUBE2V1
STRING (EMBL)UBE2V1
ZODIACUBE2V1
Ontologies - Pathways
QuickGOQ13404
Ontology : AmiGOubiquitin ligase complex  protein polyubiquitination  stimulatory C-type lectin receptor signaling pathway  protein binding  nucleus  cytoplasm  cytosol  regulation of DNA repair  postreplication repair  regulation of transcription, DNA-templated  cell differentiation  ubiquitin conjugating enzyme complex  ubiquitin protein ligase binding  UBC13-UEV1A complex  Fc-epsilon receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  protein complex  positive regulation of transcription, DNA-templated  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  protein K63-linked ubiquitination  
Ontology : EGO-EBIubiquitin ligase complex  protein polyubiquitination  stimulatory C-type lectin receptor signaling pathway  protein binding  nucleus  cytoplasm  cytosol  regulation of DNA repair  postreplication repair  regulation of transcription, DNA-templated  cell differentiation  ubiquitin conjugating enzyme complex  ubiquitin protein ligase binding  UBC13-UEV1A complex  Fc-epsilon receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  protein complex  positive regulation of transcription, DNA-templated  T cell receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  protein K63-linked ubiquitination  
NDEx NetworkUBE2V1
Atlas of Cancer Signalling NetworkUBE2V1
Wikipedia pathwaysUBE2V1
Orthology - Evolution
OrthoDB7335
GeneTree (enSembl)ENSG00000244687
Phylogenetic Trees/Animal Genes : TreeFamUBE2V1
HOVERGENQ13404
HOGENOMQ13404
Homologs : HomoloGeneUBE2V1
Homology/Alignments : Family Browser (UCSC)UBE2V1
Gene fusions - Rearrangements
Fusion : MitelmanUBE2V1/SULF2 [20q13.13/20q13.12]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2V1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2V1
dbVarUBE2V1
ClinVarUBE2V1
1000_GenomesUBE2V1 
Exome Variant ServerUBE2V1
ExAC (Exome Aggregation Consortium)UBE2V1 (select the gene name)
Genetic variants : HAPMAP7335
Genomic Variants (DGV)UBE2V1 [DGVbeta]
DECIPHER (Syndromes)20:48697661-48729735  ENSG00000244687
CONAN: Copy Number AnalysisUBE2V1 
Mutations
ICGC Data PortalUBE2V1 
TCGA Data PortalUBE2V1 
Broad Tumor PortalUBE2V1
OASIS PortalUBE2V1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2V1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2V1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2V1
DgiDB (Drug Gene Interaction Database)UBE2V1
DoCM (Curated mutations)UBE2V1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2V1 (select a term)
intoGenUBE2V1
Cancer3DUBE2V1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602995   
Orphanet
MedgenUBE2V1
Genetic Testing Registry UBE2V1
NextProtQ13404 [Medical]
TSGene7335
GENETestsUBE2V1
Huge Navigator UBE2V1 [HugePedia]
snp3D : Map Gene to Disease7335
BioCentury BCIQUBE2V1
ClinGenUBE2V1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7335
Chemical/Pharm GKB GenePA37142
Clinical trialUBE2V1
Miscellaneous
canSAR (ICR)UBE2V1 (select the gene name)
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2V1
EVEXUBE2V1
GoPubMedUBE2V1
iHOPUBE2V1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:33:09 CET 2017

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