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UBE2W (ubiquitin conjugating enzyme E2 W)

Identity

Alias_namesubiquitin-conjugating enzyme E2W (putative)
Alias_symbol (synonym)FLJ11011
Other aliasUBC-16
UBC16
HGNC (Hugo) UBE2W
LocusID (NCBI) 55284
Atlas_Id 52739
Location 8q21.11  [Link to chromosome band 8q21]
Location_base_pair Starts at 73786220 and ends at 73878910 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARMC1 (8q13.1) / UBE2W (8q21.11)COL1A1 (17q21.33) / UBE2W (8q21.11)ARMC1 8q13.1 / UBE2W 8q21.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBE2W   25616
Cards
Entrez_Gene (NCBI)UBE2W  55284  ubiquitin conjugating enzyme E2 W
AliasesUBC-16; UBC16
GeneCards (Weizmann)UBE2W
Ensembl hg19 (Hinxton)ENSG00000104343 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104343 [Gene_View]  chr8:73786220-73878910 [Contig_View]  UBE2W [Vega]
ICGC DataPortalENSG00000104343
TCGA cBioPortalUBE2W
AceView (NCBI)UBE2W
Genatlas (Paris)UBE2W
WikiGenes55284
SOURCE (Princeton)UBE2W
Genetics Home Reference (NIH)UBE2W
Genomic and cartography
GoldenPath hg38 (UCSC)UBE2W  -     chr8:73786220-73878910 -  8q21.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBE2W  -     8q21.11   [Description]    (hg19-Feb_2009)
EnsemblUBE2W - 8q21.11 [CytoView hg19]  UBE2W - 8q21.11 [CytoView hg38]
Mapping of homologs : NCBIUBE2W [Mapview hg19]  UBE2W [Mapview hg38]
OMIM614277   
Gene and transcription
Genbank (Entrez)AK001873 AK021735 AK024050 AK123531 AK225554
RefSeq transcript (Entrez)NM_001001481 NM_001001482 NM_001271015 NM_018299
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBE2W
Cluster EST : UnigeneHs.128841 [ NCBI ]
CGAP (NCI)Hs.128841
Alternative Splicing GalleryENSG00000104343
Gene ExpressionUBE2W [ NCBI-GEO ]   UBE2W [ EBI - ARRAY_EXPRESS ]   UBE2W [ SEEK ]   UBE2W [ MEM ]
Gene Expression Viewer (FireBrowse)UBE2W [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55284
GTEX Portal (Tissue expression)UBE2W
Human Protein AtlasENSG00000104343-UBE2W [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B02   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96B02  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96B02
Splice isoforms : SwissVarQ96B02
PhosPhoSitePlusQ96B02
Domaine pattern : Prosite (Expaxy)UBIQUITIN_CONJUGAT_2 (PS50127)   
Domains : Interpro (EBI)UBQ-conjugat_E2    UBQ-conjugating_enzyme/RWD   
Domain families : Pfam (Sanger)UQ_con (PF00179)   
Domain families : Pfam (NCBI)pfam00179   
Conserved Domain (NCBI)UBE2W
DMDM Disease mutations55284
Blocks (Seattle)UBE2W
PDB (SRS)2A7L    2MT6   
PDB (PDBSum)2A7L    2MT6   
PDB (IMB)2A7L    2MT6   
PDB (RSDB)2A7L    2MT6   
Structural Biology KnowledgeBase2A7L    2MT6   
SCOP (Structural Classification of Proteins)2A7L    2MT6   
CATH (Classification of proteins structures)2A7L    2MT6   
SuperfamilyQ96B02
Human Protein Atlas [tissue]ENSG00000104343-UBE2W [tissue]
Peptide AtlasQ96B02
HPRD07724
IPIIPI01018247   IPI00029300   IPI00910372   IPI00790719   IPI00973098   
Protein Interaction databases
DIP (DOE-UCLA)Q96B02
IntAct (EBI)Q96B02
FunCoupENSG00000104343
BioGRIDUBE2W
STRING (EMBL)UBE2W
ZODIACUBE2W
Ontologies - Pathways
QuickGOQ96B02
Ontology : AmiGOubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  DNA repair  protein monoubiquitination  protein monoubiquitination  misfolded or incompletely synthesized protein catabolic process  protein ubiquitination  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  protein K11-linked ubiquitination  cellular response to misfolded protein  
Ontology : EGO-EBIubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  DNA repair  protein monoubiquitination  protein monoubiquitination  misfolded or incompletely synthesized protein catabolic process  protein ubiquitination  ubiquitin protein ligase binding  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  ubiquitin protein ligase activity  protein K11-linked ubiquitination  cellular response to misfolded protein  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkUBE2W
Atlas of Cancer Signalling NetworkUBE2W
Wikipedia pathwaysUBE2W
Orthology - Evolution
OrthoDB55284
GeneTree (enSembl)ENSG00000104343
Phylogenetic Trees/Animal Genes : TreeFamUBE2W
HOVERGENQ96B02
HOGENOMQ96B02
Homologs : HomoloGeneUBE2W
Homology/Alignments : Family Browser (UCSC)UBE2W
Gene fusions - Rearrangements
Fusion : MitelmanARMC1/UBE2W [8q13.1/8q21.11]  [t(8;8)(q13;q21)]  
Fusion: TCGA_MDACCARMC1 8q13.1 UBE2W 8q21.11 LUAD
Tumor Fusion PortalUBE2W
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBE2W [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBE2W
dbVarUBE2W
ClinVarUBE2W
1000_GenomesUBE2W 
Exome Variant ServerUBE2W
ExAC (Exome Aggregation Consortium)ENSG00000104343
GNOMAD BrowserENSG00000104343
Genetic variants : HAPMAP55284
Genomic Variants (DGV)UBE2W [DGVbeta]
DECIPHERUBE2W [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBE2W 
Mutations
ICGC Data PortalUBE2W 
TCGA Data PortalUBE2W 
Broad Tumor PortalUBE2W
OASIS PortalUBE2W [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBE2W  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBE2W
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBE2W
DgiDB (Drug Gene Interaction Database)UBE2W
DoCM (Curated mutations)UBE2W (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBE2W (select a term)
intoGenUBE2W
Cancer3DUBE2W(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614277   
Orphanet
DisGeNETUBE2W
MedgenUBE2W
Genetic Testing Registry UBE2W
NextProtQ96B02 [Medical]
TSGene55284
GENETestsUBE2W
Target ValidationUBE2W
Huge Navigator UBE2W [HugePedia]
snp3D : Map Gene to Disease55284
BioCentury BCIQUBE2W
ClinGenUBE2W
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55284
Chemical/Pharm GKB GenePA142670657
Clinical trialUBE2W
Miscellaneous
canSAR (ICR)UBE2W (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBE2W
EVEXUBE2W
GoPubMedUBE2W
iHOPUBE2W
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:40:34 CET 2017

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