Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
E4,HDNB1,UBOX3,UFD2,UFD2A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10277
MIM: 613565
HGNC: 12500
Ensembl: ENSG00000130939
Variants:
dbSNP: 10277
ClinVar: 10277
TCGA: ENSG00000130939
COSMIC: UBE4B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38211530 | 2024 | UBE4B regulates p27 expression in A549 NSCLC cells through regulating the interaction of HuR and the p27 5' UTR. | 0 |
| 38211530 | 2024 | UBE4B regulates p27 expression in A549 NSCLC cells through regulating the interaction of HuR and the p27 5' UTR. | 0 |
| 37264022 | 2023 | A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling. | 2 |
| 37957138 | 2023 | UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis. | 0 |
| 37264022 | 2023 | A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling. | 2 |
| 37957138 | 2023 | UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis. | 0 |
| 35220170 | 2022 | UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling. | 2 |
| 36470669 | 2022 | Upregulated UBE4B expression correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma. | 2 |
| 35220170 | 2022 | UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling. | 2 |
| 36470669 | 2022 | Upregulated UBE4B expression correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma. | 2 |
| 34078905 | 2021 | UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation. | 24 |
| 34078905 | 2021 | UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation. | 24 |
| 31475882 | 2019 | Low UBE4B expression increases sensitivity of chemoresistant neuroblastoma cells to EGFR and STAT5 inhibition. | 7 |
| 31475882 | 2019 | Low UBE4B expression increases sensitivity of chemoresistant neuroblastoma cells to EGFR and STAT5 inhibition. | 7 |
| 29326975 | 2018 | Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. | 29 |
Citation
Dessen P
UBE4B (ubiquitination factor E4B)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/42757/ube4b
