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UBQLN4 (ubiquilin 4)

Identity

Alias_namesC1orf6
chromosome 1 open reading frame 6
Alias_symbol (synonym)A1U
UBIN
Other aliasA1Up
CIP75
HGNC (Hugo) UBQLN4
LocusID (NCBI) 56893
Atlas_Id 54746
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 156035294 and ends at 156053825 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GAPDH (12p13.31) / UBQLN4 (1q22)STT3A (11q24.2) / UBQLN4 (1q22)UBQLN4 (1q22) / ITPR3 (6p21.31)
ZSWIM4 (19p13.13) / UBQLN4 (1q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBQLN4   1237
Cards
Entrez_Gene (NCBI)UBQLN4  56893  ubiquilin 4
AliasesA1U; A1Up; C1orf6; CIP75; 
UBIN
GeneCards (Weizmann)UBQLN4
Ensembl hg19 (Hinxton)ENSG00000160803 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160803 [Gene_View]  chr1:156035294-156053825 [Contig_View]  UBQLN4 [Vega]
ICGC DataPortalENSG00000160803
TCGA cBioPortalUBQLN4
AceView (NCBI)UBQLN4
Genatlas (Paris)UBQLN4
WikiGenes56893
SOURCE (Princeton)UBQLN4
Genetics Home Reference (NIH)UBQLN4
Genomic and cartography
GoldenPath hg38 (UCSC)UBQLN4  -     chr1:156035294-156053825 -  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBQLN4  -     1q22   [Description]    (hg19-Feb_2009)
EnsemblUBQLN4 - 1q22 [CytoView hg19]  UBQLN4 - 1q22 [CytoView hg38]
Mapping of homologs : NCBIUBQLN4 [Mapview hg19]  UBQLN4 [Mapview hg38]
OMIM605440   
Gene and transcription
Genbank (Entrez)AB209566 AF113544 AF188240 AI074831 AK098368
RefSeq transcript (Entrez)NM_001304342 NM_020131
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBQLN4
Cluster EST : UnigeneHs.283739 [ NCBI ]
CGAP (NCI)Hs.283739
Alternative Splicing GalleryENSG00000160803
Gene ExpressionUBQLN4 [ NCBI-GEO ]   UBQLN4 [ EBI - ARRAY_EXPRESS ]   UBQLN4 [ SEEK ]   UBQLN4 [ MEM ]
Gene Expression Viewer (FireBrowse)UBQLN4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56893
GTEX Portal (Tissue expression)UBQLN4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRR5
Splice isoforms : SwissVarQ9NRR5
PhosPhoSitePlusQ9NRR5
Domaine pattern : Prosite (Expaxy)UBA (PS50030)    UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)STI1_HS-bd    UBA    UBA-like    Ubiquilin    Ubiquitin-rel_dom    Ubiquitin_dom   
Domain families : Pfam (Sanger)UBA (PF00627)    ubiquitin (PF00240)   
Domain families : Pfam (NCBI)pfam00627    pfam00240   
Domain families : Smart (EMBL)STI1 (SM00727)  UBA (SM00165)  UBQ (SM00213)  
Conserved Domain (NCBI)UBQLN4
DMDM Disease mutations56893
Blocks (Seattle)UBQLN4
SuperfamilyQ9NRR5
Human Protein AtlasENSG00000160803
Peptide AtlasQ9NRR5
HPRD05670
IPIIPI00024502   IPI00477826   IPI00744359   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRR5
IntAct (EBI)Q9NRR5
FunCoupENSG00000160803
BioGRIDUBQLN4
STRING (EMBL)UBQLN4
ZODIACUBQLN4
Ontologies - Pathways
QuickGOQ9NRR5
Ontology : AmiGOprotein binding  nucleus  cytoplasm  autophagosome  endoplasmic reticulum membrane  cytosol  autophagy  cytoplasmic vesicle  polyubiquitin binding  nuclear proteasome complex  cytosolic proteasome complex  regulation of proteasomal ubiquitin-dependent protein catabolic process  identical protein binding  perinuclear region of cytoplasm  negative regulation of autophagosome maturation  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  autophagosome  endoplasmic reticulum membrane  cytosol  autophagy  cytoplasmic vesicle  polyubiquitin binding  nuclear proteasome complex  cytosolic proteasome complex  regulation of proteasomal ubiquitin-dependent protein catabolic process  identical protein binding  perinuclear region of cytoplasm  negative regulation of autophagosome maturation  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkUBQLN4
Atlas of Cancer Signalling NetworkUBQLN4
Wikipedia pathwaysUBQLN4
Orthology - Evolution
OrthoDB56893
GeneTree (enSembl)ENSG00000160803
Phylogenetic Trees/Animal Genes : TreeFamUBQLN4
HOVERGENQ9NRR5
HOGENOMQ9NRR5
Homologs : HomoloGeneUBQLN4
Homology/Alignments : Family Browser (UCSC)UBQLN4
Gene fusions - Rearrangements
Fusion : MitelmanZSWIM4/UBQLN4 [19p13.13/1q22]  [t(1;19)(q22;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBQLN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBQLN4
dbVarUBQLN4
ClinVarUBQLN4
1000_GenomesUBQLN4 
Exome Variant ServerUBQLN4
ExAC (Exome Aggregation Consortium)UBQLN4 (select the gene name)
Genetic variants : HAPMAP56893
Genomic Variants (DGV)UBQLN4 [DGVbeta]
DECIPHERUBQLN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBQLN4 
Mutations
ICGC Data PortalUBQLN4 
TCGA Data PortalUBQLN4 
Broad Tumor PortalUBQLN4
OASIS PortalUBQLN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBQLN4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBQLN4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBQLN4
DgiDB (Drug Gene Interaction Database)UBQLN4
DoCM (Curated mutations)UBQLN4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBQLN4 (select a term)
intoGenUBQLN4
Cancer3DUBQLN4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605440   
Orphanet
MedgenUBQLN4
Genetic Testing Registry UBQLN4
NextProtQ9NRR5 [Medical]
TSGene56893
GENETestsUBQLN4
Target ValidationUBQLN4
Huge Navigator UBQLN4 [HugePedia]
snp3D : Map Gene to Disease56893
BioCentury BCIQUBQLN4
ClinGenUBQLN4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56893
Chemical/Pharm GKB GenePA25619
Clinical trialUBQLN4
Miscellaneous
canSAR (ICR)UBQLN4 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBQLN4
EVEXUBQLN4
GoPubMedUBQLN4
iHOPUBQLN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:01:44 CEST 2017

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