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UBR4 (ubiquitin protein ligase E3 component n-recognin 4)

Identity

Other namesRBAF600
ZUBR1
p600
HGNC (Hugo) UBR4
LocusID (NCBI) 23352
Location 1p36.13
Location_base_pair Starts at 19401000 and ends at 19536746 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UBR4   30313
Entrez_Gene (NCBI)UBR4  23352  ubiquitin protein ligase E3 component n-recognin 4
Cards
GeneCards (Weizmann)UBR4
Ensembl (Hinxton)ENSG00000127481 [Gene_View]  chr1:19401000-19536746 [Contig_View]  UBR4 [Vega]
AceView (NCBI)UBR4
Genatlas (Paris)UBR4
SOURCE (Stanford)NM_020765
Genomic and cartography
GoldenPath (UCSC)UBR4  -  1p36.13   chr1:19401000-19536746 -  1p36.13   [Description]    (hg19-Feb_2009)
EnsemblUBR4 - 1p36.13 [CytoView]
Mapping of homologs : NCBIUBR4 [Mapview]
OMIM609890   
Gene and transcription
Genbank (Entrez)AA748129 AB007931 AB037728 AF055010 AF348492
RefSeq transcript (SRS)NM_020765
RefSeq transcript (Entrez)NM_020765
RefSeq genomic (SRS)AC_000133 NC_000001 NC_018912 NG_027669 NT_004610 NW_001838573 NW_004077990
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_027669 NT_004610 NW_001838573 NW_004077990
Consensus coding sequences : CCDS (NCBI)UBR4
Cluster EST : UnigeneHs.649405 [ SRS ] Hs.649405 [ NCBI ]
CGAP (NCI)Hs.649405
Alternative Splicing : Fast-db (Paris)GSHG0001803
Alternative Splicing GalleryENSG00000127481
Gene ExpressionUBR4 [ NCBI-GEO ]   UBR4 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T4S7 (SRS) Q5T4S7 (Uniprot)
NextProtQ5T4S7
With graphics : InterProQ5T4S7
Splice isoforms : SwissVarQ5T4S7(Swissvar)
Domaine pattern : Prosite (SRS)ZF_UBR (PS51157)   
Domaine pattern : Prosite (Expaxy)ZF_UBR (PS51157)   
Domains : Interpro (SRS)E3_Ub_ligase_UBR4    Znf_N-recognin   
Domains : Interpro (EBI)E3_Ub_ligase_UBR4    Znf_N-recognin   
Related proteins : CluSTrQ5T4S7
Domain families : Pfam (SRS)E3_UbLigase_R4 (PF13764)    zf-UBR (PF02207)   
Domain families : Pfam (Sanger)E3_UbLigase_R4 (PF13764)    zf-UBR (PF02207)   
Domain families : Pfam (NCBI)pfam13764    pfam02207   
DMDM23352
Blocks (Seattle)Q5T4S7
Human Protein AtlasENSG00000127481
HPRD10184
IPIIPI00843999   IPI00746934   IPI00646605   IPI00640981   IPI00180305   IPI00386907   IPI01009566   IPI00445529   IPI00514902   IPI00942028   
Protein Interaction databases
DIP (DOE-UCLA)Q5T4S7
IntAct (EBI)Q5T4S7
FunCoupENSG00000127481
REACTOMEUBR4
Protein Interaction Database23352
BioGRIDUBR4
InParanoidQ5T4S7
Interologous Interaction database Q5T4S7
IntegromeDBUBR4
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)UBR4
SNP (GeneSNP Utah)UBR4
SNP : HGBaseUBR4
Genetic variants : HAPMAPUBR4
Somatic Mutations in Cancer : COSMICUBR4 
CONAN: Copy Number AnalysisUBR4 
Mutations and Diseases : HGMDUBR4
OMIM609890   
GENETests609890   
Disease Genetic AssociationUBR4
Huge Navigator UBR4 [HugePedia]  UBR4 [HugeCancerGEM]
Genomic VariantsUBR4  UBR4 [DGVbeta]
ClinVarUBR4
snp3D : Map Gene to Disease23352
General knowledge
Homologs : HomoloGeneUBR4
Homology/Alignments : Family Browser (UCSC)UBR4
Phylogenetic Trees/Animal Genes : TreeFamUBR4
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Chemical/Protein Interactions : CTD23352
Chemical/Pharm GKB GenePA162407958
Clinical trialUBR4
Cancer Resource (Charite)ENSG00000127481
Ontology : AmiGOubiquitin-protein ligase activity  calmodulin binding  nucleus  cytoplasm  cytoskeleton  zinc ion binding  integral to membrane  virus-host interaction  
Ontology : EGO-EBIubiquitin-protein ligase activity  calmodulin binding  nucleus  cytoplasm  cytoskeleton  zinc ion binding  integral to membrane  virus-host interaction  
Other databases
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
PubGeneUBR4
iHOPUBR4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:35:35 CEST 2013
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