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UBTF (upstream binding transcription factor, RNA polymerase I)

Identity

Alias_symbol (synonym)UBF
NOR-90
UBF1
UBF2
Other aliasUBF-1
HGNC (Hugo) UBTF
LocusID (NCBI) 7343
Atlas_Id 45793
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 44205033 and ends at 44220882 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LOC100507412 (-) / UBTF (17q21.31)UBTF (17q21.31) / ETV4 (17q21.31)UBTF (17q21.31) / MYH9 (22q12.3)
UBTF (17q21.31) / SEC61A1 (3q21.3)UBTF (17q21.31) / TK1 (17q25.3)UBTF (17q21.31) / UBTF (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)UBTF   12511
Cards
Entrez_Gene (NCBI)UBTF  7343  upstream binding transcription factor, RNA polymerase I
AliasesNOR-90; UBF; UBF-1; UBF1; 
UBF2
GeneCards (Weizmann)UBTF
Ensembl hg19 (Hinxton)ENSG00000108312 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108312 [Gene_View]  chr17:44205033-44220882 [Contig_View]  UBTF [Vega]
ICGC DataPortalENSG00000108312
TCGA cBioPortalUBTF
AceView (NCBI)UBTF
Genatlas (Paris)UBTF
WikiGenes7343
SOURCE (Princeton)UBTF
Genetics Home Reference (NIH)UBTF
Genomic and cartography
GoldenPath hg38 (UCSC)UBTF  -     chr17:44205033-44220882 -  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBTF  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblUBTF - 17q21.31 [CytoView hg19]  UBTF - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIUBTF [Mapview hg19]  UBTF [Mapview hg38]
OMIM600673   
Gene and transcription
Genbank (Entrez)AF289595 AK291733 AK292518 AK292577 AK296917
RefSeq transcript (Entrez)NM_001076683 NM_001076684 NM_014233
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBTF
Cluster EST : UnigeneHs.89781 [ NCBI ]
CGAP (NCI)Hs.89781
Alternative Splicing GalleryENSG00000108312
Gene ExpressionUBTF [ NCBI-GEO ]   UBTF [ EBI - ARRAY_EXPRESS ]   UBTF [ SEEK ]   UBTF [ MEM ]
Gene Expression Viewer (FireBrowse)UBTF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7343
GTEX Portal (Tissue expression)UBTF
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17480   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17480  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17480
Splice isoforms : SwissVarP17480
PhosPhoSitePlusP17480
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_5    HMG_box_dom   
Domain families : Pfam (Sanger)HMG_box (PF00505)    HMG_box_2 (PF09011)    HMG_box_5 (PF14887)   
Domain families : Pfam (NCBI)pfam00505    pfam09011    pfam14887   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)UBTF
DMDM Disease mutations7343
Blocks (Seattle)UBTF
PDB (SRS)1K99    1L8Y    1L8Z    2HDZ   
PDB (PDBSum)1K99    1L8Y    1L8Z    2HDZ   
PDB (IMB)1K99    1L8Y    1L8Z    2HDZ   
PDB (RSDB)1K99    1L8Y    1L8Z    2HDZ   
Structural Biology KnowledgeBase1K99    1L8Y    1L8Z    2HDZ   
SCOP (Structural Classification of Proteins)1K99    1L8Y    1L8Z    2HDZ   
CATH (Classification of proteins structures)1K99    1L8Y    1L8Z    2HDZ   
SuperfamilyP17480
Human Protein AtlasENSG00000108312
Peptide AtlasP17480
HPRD02814
IPIIPI00014533   IPI00220833   IPI00384556   IPI00979003   IPI00976760   IPI00981097   IPI00979797   
Protein Interaction databases
DIP (DOE-UCLA)P17480
IntAct (EBI)P17480
FunCoupENSG00000108312
BioGRIDUBTF
STRING (EMBL)UBTF
ZODIACUBTF
Ontologies - Pathways
QuickGOP17480
Ontology : AmiGORNA polymerase I CORE element sequence-specific DNA binding  RNA polymerase I upstream control element sequence-specific DNA binding  fibrillar center  chromatin binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleolus  nucleolus  regulation of transcription from RNA polymerase I promoter  transcription from RNA polymerase I promoter  transcription initiation from RNA polymerase I promoter  transcription elongation from RNA polymerase I promoter  termination of RNA polymerase I transcription  positive regulation of transcription from RNA polymerase I promoter  regulation of glucose mediated signaling pathway  
Ontology : EGO-EBIRNA polymerase I CORE element sequence-specific DNA binding  RNA polymerase I upstream control element sequence-specific DNA binding  fibrillar center  chromatin binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleolus  nucleolus  regulation of transcription from RNA polymerase I promoter  transcription from RNA polymerase I promoter  transcription initiation from RNA polymerase I promoter  transcription elongation from RNA polymerase I promoter  termination of RNA polymerase I transcription  positive regulation of transcription from RNA polymerase I promoter  regulation of glucose mediated signaling pathway  
NDEx NetworkUBTF
Atlas of Cancer Signalling NetworkUBTF
Wikipedia pathwaysUBTF
Orthology - Evolution
OrthoDB7343
GeneTree (enSembl)ENSG00000108312
Phylogenetic Trees/Animal Genes : TreeFamUBTF
HOVERGENP17480
HOGENOMP17480
Homologs : HomoloGeneUBTF
Homology/Alignments : Family Browser (UCSC)UBTF
Gene fusions - Rearrangements
Fusion : MitelmanUBTF/ETV4 [17q21.31/17q21.31]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBTF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UBTF
dbVarUBTF
ClinVarUBTF
1000_GenomesUBTF 
Exome Variant ServerUBTF
ExAC (Exome Aggregation Consortium)UBTF (select the gene name)
Genetic variants : HAPMAP7343
Genomic Variants (DGV)UBTF [DGVbeta]
DECIPHERUBTF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBTF 
Mutations
ICGC Data PortalUBTF 
TCGA Data PortalUBTF 
Broad Tumor PortalUBTF
OASIS PortalUBTF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBTF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDUBTF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBTF
DgiDB (Drug Gene Interaction Database)UBTF
DoCM (Curated mutations)UBTF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBTF (select a term)
intoGenUBTF
Cancer3DUBTF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600673   
Orphanet
MedgenUBTF
Genetic Testing Registry UBTF
NextProtP17480 [Medical]
TSGene7343
GENETestsUBTF
Target ValidationUBTF
Huge Navigator UBTF [HugePedia]
snp3D : Map Gene to Disease7343
BioCentury BCIQUBTF
ClinGenUBTF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7343
Chemical/Pharm GKB GenePA37158
Clinical trialUBTF
Miscellaneous
canSAR (ICR)UBTF (select the gene name)
Probes
Litterature
PubMed109 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBTF
EVEXUBTF
GoPubMedUBTF
iHOPUBTF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:37:15 CEST 2017

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