Atlas of Genetics and Cytogenetics in Oncology and Haematology

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UBXN1 (UBX domain protein 1)

Identity

Alias (NCBI)2B28
SAKS1
UBXD10
HGNC (Hugo) UBXN1
HGNC Alias symbLOC51035
2B28
UBXD10
SAKS1
HGNC Alias nameSAPK substrate protein 1
LocusID (NCBI) 51035
Atlas_Id 75445
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62676498 and ends at 62679117 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EEF1G (11q12.3) / UBXN1 (11q12.3)UBXN1 (11q12.3) / BSCL2 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  UBXN1/BSCL2 (11q12)
UBXN1/BSCL2 (11q12)

External links

Nomenclature
HGNC (Hugo)UBXN1   18402
Cards
Entrez_Gene (NCBI)UBXN1    UBX domain protein 1
Aliases2B28; SAKS1; UBXD10
GeneCards (Weizmann)UBXN1
Ensembl hg19 (Hinxton)ENSG00000162191 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162191 [Gene_View]  ENSG00000162191 [Sequence]  chr11:62676498-62679117 [Contig_View]  UBXN1 [Vega]
ICGC DataPortalENSG00000162191
TCGA cBioPortalUBXN1
AceView (NCBI)UBXN1
Genatlas (Paris)UBXN1
SOURCE (Princeton)UBXN1
Genetics Home Reference (NIH)UBXN1
Genomic and cartography
GoldenPath hg38 (UCSC)UBXN1  -     chr11:62676498-62679117 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)UBXN1  -     11q12.3   [Description]    (hg19-Feb_2009)
GoldenPathUBXN1 - 11q12.3 [CytoView hg19]  UBXN1 - 11q12.3 [CytoView hg38]
ImmunoBaseENSG00000162191
genome Data Viewer NCBIUBXN1 [Mapview hg19]  
OMIM616378   
Gene and transcription
Genbank (Entrez)AI498746 AK054832 AK297856 AK300542 AK303471
RefSeq transcript (Entrez)NM_001286077 NM_001286078 NM_015853
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)UBXN1
Alternative Splicing GalleryENSG00000162191
Gene ExpressionUBXN1 [ NCBI-GEO ]   UBXN1 [ EBI - ARRAY_EXPRESS ]   UBXN1 [ SEEK ]   UBXN1 [ MEM ]
Gene Expression Viewer (FireBrowse)UBXN1 [ Firebrowse - Broad ]
GenevisibleExpression of UBXN1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51035
GTEX Portal (Tissue expression)UBXN1
Human Protein AtlasENSG00000162191-UBXN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ04323   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ04323  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ04323
Splice isoforms : SwissVarQ04323
PhosPhoSitePlusQ04323
Domaine pattern : Prosite (Expaxy)UBA (PS50030)    UBX (PS50033)   
Domains : Interpro (EBI)UBA    UBA-like_sf    UBA_UBXN1    Ubiquitin-like_domsf    UBX_dom   
Domain families : Pfam (Sanger)UBA (PF00627)    UBX (PF00789)   
Domain families : Pfam (NCBI)pfam00627    pfam00789   
Domain families : Smart (EMBL)UBA (SM00165)  UBX (SM00166)  
Conserved Domain (NCBI)UBXN1
Blocks (Seattle)UBXN1
SuperfamilyQ04323
Human Protein Atlas [tissue]ENSG00000162191-UBXN1 [tissue]
Peptide AtlasQ04323
HPRD11266
IPIIPI00027378   IPI00396563   IPI00910402   IPI01014777   IPI00979280   IPI00982790   IPI00978573   
Protein Interaction databases
DIP (DOE-UCLA)Q04323
IntAct (EBI)Q04323
BioGRIDUBXN1
STRING (EMBL)UBXN1
ZODIACUBXN1
Ontologies - Pathways
QuickGOQ04323
Ontology : AmiGOprotein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  protein folding  viral process  dendrite  negative regulation of protein ubiquitination  polyubiquitin modification-dependent protein binding  ubiquitin protein ligase binding  negative regulation of proteasomal ubiquitin-dependent protein catabolic process  VCP-NPL4-UFD1 AAA ATPase complex  K48-linked polyubiquitin modification-dependent protein binding  neuronal cell body  ubiquitin binding  proteasome-mediated ubiquitin-dependent protein catabolic process  ATPase binding  K6-linked polyubiquitin modification-dependent protein binding  negative regulation of protein K48-linked deubiquitination  negative regulation of ERAD pathway  proteasome regulatory particle binding  negative regulation of ubiquitin-specific protease activity  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  protein folding  viral process  dendrite  negative regulation of protein ubiquitination  polyubiquitin modification-dependent protein binding  ubiquitin protein ligase binding  negative regulation of proteasomal ubiquitin-dependent protein catabolic process  VCP-NPL4-UFD1 AAA ATPase complex  K48-linked polyubiquitin modification-dependent protein binding  neuronal cell body  ubiquitin binding  proteasome-mediated ubiquitin-dependent protein catabolic process  ATPase binding  K6-linked polyubiquitin modification-dependent protein binding  negative regulation of protein K48-linked deubiquitination  negative regulation of ERAD pathway  proteasome regulatory particle binding  negative regulation of ubiquitin-specific protease activity  
NDEx NetworkUBXN1
Atlas of Cancer Signalling NetworkUBXN1
Wikipedia pathwaysUBXN1
Orthology - Evolution
OrthoDB51035
GeneTree (enSembl)ENSG00000162191
Phylogenetic Trees/Animal Genes : TreeFamUBXN1
HOGENOMQ04323
Homologs : HomoloGeneUBXN1
Homology/Alignments : Family Browser (UCSC)UBXN1
Gene fusions - Rearrangements
Fusion : QuiverUBXN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerUBXN1 [hg38]
dbVarUBXN1
ClinVarUBXN1
MonarchUBXN1
1000_GenomesUBXN1 
Exome Variant ServerUBXN1
GNOMAD BrowserENSG00000162191
Varsome BrowserUBXN1
Genomic Variants (DGV)UBXN1 [DGVbeta]
DECIPHERUBXN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisUBXN1 
Mutations
ICGC Data PortalUBXN1 
TCGA Data PortalUBXN1 
Broad Tumor PortalUBXN1
OASIS PortalUBXN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICUBXN1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DUBXN1
Mutations and Diseases : HGMDUBXN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch UBXN1
DgiDB (Drug Gene Interaction Database)UBXN1
DoCM (Curated mutations)UBXN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)UBXN1 (select a term)
intoGenUBXN1
Cancer3DUBXN1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616378   
Orphanet
DisGeNETUBXN1
MedgenUBXN1
Genetic Testing Registry UBXN1
NextProtQ04323 [Medical]
GENETestsUBXN1
Target ValidationUBXN1
Huge Navigator UBXN1 [HugePedia]
ClinGenUBXN1
Clinical trials, drugs, therapy
MyCancerGenomeUBXN1
Protein Interactions : CTD
Pharm GKB GenePA162408336
Clinical trialUBXN1
Miscellaneous
canSAR (ICR)UBXN1 (select the gene name)
HarmonizomeUBXN1
DataMed IndexUBXN1
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineUBXN1
EVEXUBXN1
GoPubMedUBXN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:34:04 CET 2020
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