UBXN7 (UBX domain protein 7)

2014-11-01  

Identity

HGNC
LOCATION
3q29
LOCUSID
ALIAS
UBXD7
FUSION GENES

Other Information

Locus ID:

NCBI: 26043
MIM: 616379
HGNC: 29119
Ensembl: ENSG00000163960

Variants:

dbSNP: 26043
ClinVar: 26043
TCGA: ENSG00000163960
COSMIC: UBXN7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163960ENST00000296328O94888
ENSG00000163960ENST00000381887H7BYF4
ENSG00000163960ENST00000413584C9JD50
ENSG00000163960ENST00000428095C9JAT7
ENSG00000163960ENST00000429160F8WB69

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187753132008UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.147
216458542011Hierarchical binding of cofactors to the AAA ATPase p97.40
225373862012UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.28
282748782017Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase.3

Citation

Dessen P

UBXN7 (UBX domain protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75451/ubxn7