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UCHL3 (ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase))

Identity

Other namesUCH-L3
HGNC (Hugo) UCHL3
LocusID (NCBI) 7347
Atlas_Id 42762
Location 13q22.2
Location_base_pair Starts at 76123616 and ends at 76180156 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UCHL3   12515
Cards
Entrez_Gene (NCBI)UCHL3  7347  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
GeneCards (Weizmann)UCHL3
Ensembl hg19 (Hinxton)ENSG00000118939 [Gene_View]  chr13:76123616-76180156 [Contig_View]  UCHL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000118939 [Gene_View]  chr13:76123616-76180156 [Contig_View]  UCHL3 [Vega]
ICGC DataPortalENSG00000118939
TCGA cBioPortalUCHL3
AceView (NCBI)UCHL3
Genatlas (Paris)UCHL3
WikiGenes7347
SOURCE (Princeton)UCHL3
Genomic and cartography
GoldenPath hg19 (UCSC)UCHL3  -     chr13:76123616-76180156 +  13q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)UCHL3  -     13q22.2   [Description]    (hg38-Dec_2013)
EnsemblUCHL3 - 13q22.2 [CytoView hg19]  UCHL3 - 13q22.2 [CytoView hg38]
Mapping of homologs : NCBIUCHL3 [Mapview hg19]  UCHL3 [Mapview hg38]
OMIM603090   
Gene and transcription
Genbank (Entrez)AA234624 AK313665 BC018125 BQ427804 BT019359
RefSeq transcript (Entrez)NM_001270952 NM_006002
RefSeq genomic (Entrez)NC_000013 NC_018924 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)UCHL3
Cluster EST : UnigeneHs.162241 [ NCBI ]
CGAP (NCI)Hs.162241
Alternative Splicing : Fast-db (Paris)GSHG0008177
Alternative Splicing GalleryENSG00000118939
Gene ExpressionUCHL3 [ NCBI-GEO ]     UCHL3 [ SEEK ]   UCHL3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15374 (Uniprot)
NextProtP15374  [Medical]
With graphics : InterProP15374
Splice isoforms : SwissVarP15374 (Swissvar)
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.123.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)UCH_1 (PS00140)   
Domains : Interpro (EBI)Peptidase_C12_UCH   
Related proteins : CluSTrP15374
Domain families : Pfam (Sanger)Peptidase_C12 (PF01088)   
Domain families : Pfam (NCBI)pfam01088   
DMDM Disease mutations7347
Blocks (Seattle)P15374
PDB (SRS)1UCH    1XD3   
PDB (PDBSum)1UCH    1XD3   
PDB (IMB)1UCH    1XD3   
PDB (RSDB)1UCH    1XD3   
Human Protein AtlasENSG00000118939
Peptide AtlasP15374
HPRD04367
IPIIPI00011250   IPI00514154   
Protein Interaction databases
DIP (DOE-UCLA)P15374
IntAct (EBI)P15374
FunCoupENSG00000118939
BioGRIDUCHL3
IntegromeDBUCHL3
STRING (EMBL)UCHL3
Ontologies - Pathways
QuickGOP15374
Ontology : AmiGOubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cytoplasm  ubiquitin-dependent protein catabolic process  peptidase activity  protein catabolic process  ubiquitin binding  extracellular exosome  
Ontology : EGO-EBIubiquitin-specific protease activity  protein binding  nucleus  nucleoplasm  cytoplasm  ubiquitin-dependent protein catabolic process  peptidase activity  protein catabolic process  ubiquitin binding  extracellular exosome  
Protein Interaction DatabaseUCHL3
DoCM (Curated mutations)UCHL3
Wikipedia pathwaysUCHL3
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerUCHL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)UCHL3
dbVarUCHL3
ClinVarUCHL3
1000_GenomesUCHL3 
Exome Variant ServerUCHL3
SNP (GeneSNP Utah)UCHL3
SNP : HGBaseUCHL3
Genetic variants : HAPMAPUCHL3
Genomic Variants (DGV)UCHL3 [DGVbeta]
Mutations
ICGC Data PortalUCHL3 
TCGA Data PortalUCHL3 
Tumor PortalUCHL3
Somatic Mutations in Cancer : COSMICUCHL3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)13:76123616-76180156
CONAN: Copy Number AnalysisUCHL3 
Mutations and Diseases : HGMDUCHL3
OMIM603090   
MedgenUCHL3
NextProtP15374 [Medical]
GENETestsUCHL3
Disease Genetic AssociationUCHL3
Huge Navigator UCHL3 [HugePedia]  UCHL3 [HugeCancerGEM]
snp3D : Map Gene to Disease7347
DGIdb (Drug Gene Interaction db)UCHL3
General knowledge
Homologs : HomoloGeneUCHL3
Homology/Alignments : Family Browser (UCSC)UCHL3
Phylogenetic Trees/Animal Genes : TreeFamUCHL3
Chemical/Protein Interactions : CTD7347
Chemical/Pharm GKB GenePA37162
Clinical trialUCHL3
Cancer Resource (Charite)ENSG00000118939
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
CoreMineUCHL3
GoPubMedUCHL3
iHOPUCHL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 20:18:18 CEST 2015

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