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UCHL3 (ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase))

Identity

Other namesUCH-L3
HGNC (Hugo) UCHL3
LocusID (NCBI) 7347
Location 13q22.2
Location_base_pair Starts at 76123616 and ends at 76180156 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)UCHL3   12515
Entrez_Gene (NCBI)UCHL3  7347  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Cards
GeneCards (Weizmann)UCHL3
Ensembl (Hinxton)ENSG00000118939 [Gene_View]  chr13:76123616-76180156 [Contig_View]  UCHL3 [Vega]
AceView (NCBI)UCHL3
Genatlas (Paris)UCHL3
SOURCE (Stanford)NM_001270952 NM_006002
Genomic and cartography
GoldenPath (UCSC)UCHL3  -  13q22.2   chr13:76123616-76180156 +  13q22.2   [Description]    (hg19-Feb_2009)
EnsemblUCHL3 - 13q22.2 [CytoView]
Mapping of homologs : NCBIUCHL3 [Mapview]
OMIM603090   
Gene and transcription
Genbank (Entrez)AA234624 AK313665 BC018125 BQ427804 BT019359
RefSeq transcript (SRS)NM_001270952 NM_006002
RefSeq transcript (Entrez)NM_001270952 NM_006002
RefSeq genomic (SRS)AC_000145 NC_000013 NC_018924 NT_024524 NW_001838082 NW_004078077
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NT_024524 NW_001838082 NW_004078077
Consensus coding sequences : CCDS (NCBI)UCHL3
Cluster EST : UnigeneHs.162241 [ SRS ] Hs.162241 [ NCBI ]
CGAP (NCI)Hs.162241
Alternative Splicing : Fast-db (Paris)GSHG0008177
Alternative Splicing GalleryENSG00000118939
Gene ExpressionUCHL3 [ NCBI-GEO ]   UCHL3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15374 (SRS) P15374 (Uniprot)
NextProtP15374
With graphics : InterProP15374
Splice isoforms : SwissVarP15374(Swissvar)
Domaine pattern : Prosite (SRS)UCH_1 (PS00140)   
Domaine pattern : Prosite (Expaxy)UCH_1 (PS00140)   
Domains : Interpro (SRS)Peptidase_C12   
Domains : Interpro (EBI)Peptidase_C12   
Related proteins : CluSTrP15374
Domain families : Pfam (SRS)Peptidase_C12 (PF01088)   
Domain families : Pfam (Sanger)Peptidase_C12 (PF01088)   
Domain families : Pfam (NCBI)pfam01088   
DMDM7347
Blocks (Seattle)P15374
PDB (SRS)1UCH    1XD3   
PDB (PDBSum)1UCH    1XD3   
PDB (IMB)1UCH    1XD3   
PDB (RSDB)1UCH    1XD3   
Human Protein AtlasENSG00000118939
HPRD04367
IPIIPI00011250   IPI00514154   
Protein Interaction databases
DIP (DOE-UCLA)P15374
IntAct (EBI)P15374
FunCoupENSG00000118939
REACTOMEUCHL3
Protein Interaction Database7347
BioGRIDUCHL3
InParanoidP15374
Interologous Interaction database P15374
IntegromeDBUCHL3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)UCHL3
SNP (GeneSNP Utah)UCHL3
SNP : HGBaseUCHL3
Genetic variants : HAPMAPUCHL3
Somatic Mutations in Cancer : COSMICUCHL3 
CONAN: Copy Number AnalysisUCHL3 
Mutations and Diseases : HGMDUCHL3
OMIM603090   
GENETests603090   
Disease Genetic AssociationUCHL3
Huge Navigator UCHL3 [HugePedia]  UCHL3 [HugeCancerGEM]
Genomic VariantsUCHL3  UCHL3 [DGVbeta]
snp3D : Map Gene to Disease7347
General knowledge
Homologs : HomoloGeneUCHL3
Homology/Alignments : Family Browser (UCSC)UCHL3
Phylogenetic Trees/Animal Genes : TreeFamUCHL3
Catalytic activity : Enzyme3.4.19.12 [ Enzyme-Expasy ]   3.4.19.12 [ Enzyme-SRS ]   3.4.19.12 [ IntEnz-EBI ]   3.4.19.12 [ BRENDA ]   3.4.19.12 [ KEGG ]   
Chemical/Protein Interactions : CTD7347
Chemical/Pharm GKB GenePA37162
Clinical trialUCHL3
Cancer Resource (Charite)ENSG00000118939
Ontology : AmiGOubiquitin thiolesterase activity  nucleus  cytoplasm  cytoplasm  mitochondrion  ubiquitin-dependent protein catabolic process  peptidase activity  cysteine-type peptidase activity  protein catabolic process  ubiquitin binding  
Ontology : EGO-EBIubiquitin thiolesterase activity  nucleus  cytoplasm  cytoplasm  mitochondrion  ubiquitin-dependent protein catabolic process  peptidase activity  cysteine-type peptidase activity  protein catabolic process  ubiquitin binding  
Other databases
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
PubGeneUCHL3
iHOPUCHL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:34:14 CEST 2013
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